{"entity": "researcher", "timestamp": "2026-08-20T20:40:29.919Z", "family": "De Rossi", "given": "Mar\u00eda Cecilia", "initials": "MC", "orcid": "0000-0001-8138-0663", "affiliations": ["Departamento de Qu\u00edmica Biol\u00f3gica, Facultad de Ciencias Exactas y Naturales, CONICET - Universidad de Buenos Aires, Instituto de Qu\u00edmica Biol\u00f3gica (IQUIBICEN), Buenos Aires, Argentina."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/c55efa3c9b3945da87ae123629552462.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/c55efa3c9b3945da87ae123629552462"}}, "publications": [{"entity": "publication", "iuid": "a6ade267c1224572a8ab68836f302f19", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/a6ade267c1224572a8ab68836f302f19.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/a6ade267c1224572a8ab68836f302f19"}}, "title": "Dynamical organization of vimentin intermediate filaments in living cells revealed by MoNaLISA nanoscopy.", "authors": [{"family": "Smoler", "given": "Mariano", "initials": "M"}, {"family": "Pennacchietti", "given": "Francesca", "initials": "F"}, {"family": "De Rossi", "given": "Mar\u00eda Cecilia", "initials": "MC", "orcid": "0000-0001-8138-0663", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c55efa3c9b3945da87ae123629552462.json"}}, {"family": "Bruno", "given": "Luciana", "initials": "L", "orcid": "0000-0003-0146-2699", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0148206b33b14cfcad92cf4c71a5ca96.json"}}, {"family": "Testa", "given": "Ilaria", "initials": "I"}, {"family": "Levi", "given": "Valeria", "initials": "V", "orcid": "0000-0002-1666-4675", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1c0a6e94fe4f4ce7975fce78ba350501.json"}}], "type": "journal article", "published": "2025-02-12", "journal": {"title": "Biosci. Rep.", "issn": "1573-4935", "volume": "45", "issue": "2", "issn-l": "0144-8463"}, "abstract": "Intermediate filaments are intimately involved in the mechanical behavior of cells. Unfortunately, the resolution of optical microscopy limits our understanding of their organization. Here, we combined nanoscopy, single-filament tracking, and numerical simulations to inspect the dynamical organization of vimentin intermediate filaments in live cells. We show that a higher proportion of peripheral versus perinuclear vimentin pools are constrained in their lateral motion in the seconds time window, probably due to their cross-linking to other cytoskeletal networks. In a longer time scale, active forces become evident and affect similarly both pools of filaments. Our results provide a detailed description of the dynamical organization of the vimentin network in live cells and give some cues on its response to mechanical stimuli.", "doi": "10.1042/BSR20241133", "pmid": "39936518", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC12127793"}, {"db": "pii", "key": "235347"}], "notes": [], "created": "2026-08-20T09:28:24.105Z", "modified": "2026-08-20T09:28:24.253Z"}]}