{"entity": "researcher", "timestamp": "2026-09-23T18:26:31.824Z", "family": "Pahnke", "given": "Simon", "initials": "S", "orcid": "0000-0002-3541-2027", "affiliations": ["Department of Immunology, Genetics and Pathology, Cancer Precision Medicine, Uppsala University, Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/c05498e91efd4439836a7e322b404523.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/c05498e91efd4439836a7e322b404523"}}, "publications": [{"entity": "publication", "iuid": "157956cab1504950b2874e0fbc321774", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/157956cab1504950b2874e0fbc321774.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/157956cab1504950b2874e0fbc321774"}}, "title": "Strict self-isolation did not protect Swedish cancer patients on active treatment from the risk of becoming seropositive for SARS-CoV-2.", "authors": [{"family": "Ginman", "given": "Beatrice", "initials": "B"}, {"family": "Pahnke", "given": "Simon", "initials": "S", "orcid": "0000-0002-3541-2027", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c05498e91efd4439836a7e322b404523.json"}}, {"family": "Freyhult", "given": "Eva", "initials": "E"}, {"family": "Hoffman", "given": "Tove", "initials": "T"}, {"family": "Kolstad", "given": "Linda", "initials": "L"}, {"family": "R\u00f6nnberg", "given": "Bengt", "initials": "B"}, {"family": "Lundkvist", "given": "\u00c5ke", "initials": "\u00c5"}, {"family": "Hamberg Levedahl", "given": "Kerstin", "initials": "K"}, {"family": "Enblad", "given": "Gunilla", "initials": "G"}, {"family": "Glimelius", "given": "Ingrid", "initials": "I", "orcid": "0000-0001-6158-3041", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/e3e9c94f8a6a45978cf6a428fb108db2.json"}}], "type": "journal article", "published": "2023-12-00", "journal": {"title": "Acta Oncol", "issn": "1651-226X", "volume": "62", "issue": "12", "pages": "1707-1715", "issn-l": "0284-186X"}, "abstract": "Swedish recommendations to reduce the risk of COVID-19 relied on each citizen's own sense of responsibility rather than mandatory lockdowns. We studied how COVID-19-related self-isolation and anxiety correlated to SARS-CoV-2 seropositivity and PCR-positivity in patients with active cancer treatment.\n\nIn a longitudinal cohort study at Uppsala University Hospital patients and cancer personnel were included between April 1st 2020 to August 1st 2020. Serological testing for SARS-CoV-2 was done every 8-12-weeks until 30 March 2021. Patients completed a survey at inclusion regarding self-reported COVID-19-related anxiety and self-isolation.\n\nA total of 622 patients [n = 475 with solid malignancies (SM), n = 147 with haematological malignancies (HM)], and 358 healthcare personnel were included. The seropositivity rate was lower for patients than for personnel; 10.5% for SM patients, 6.8% for HM patients, and 16.2% for personnel (p = 0.005). Strict adherence to self-isolation guidelines was reported by 54% of patients but was not associated with a lower risk of becoming seropositive [OR = 1.4 (0.8-2.5), p = 0.2]. High anxiety was expressed by 32% of patients, more often by SM patients than HM patients (34% vs 25% [OR = 1.6 (1.1-2.5, p = 0.03)]). Female gender [OR = 3.5 (2.4-5.2), p < 0.001] and being born outside of Europe [OR = 2.9 (1.4-6.4), p = 0.007] were both associated with high anxiety. Patients reporting high anxiety became seropositive to a similar degree as those with low anxiety [OR = 0.7 (0.3-1.2), p = 0.2]. HM patients with PCR-positive COVID-19 were more likely than SM patients to require oxygen therapy, including non-invasive ventilation/intubation (69% vs. 26%, p = 0.005).\n\nFor Swedish patients on active cancer treatment, high self-assessed COVID-19-related anxiety or strict adherence to self-isolation guidelines were not associated with a lower risk of COVID-19. Patients with HM were less likely to develop serological antibody response after COVID-19 and were more likely to require advanced hospital care, but expressed less COVID-19-related anxiety than patients with SM.", "doi": "10.1080/0284186X.2023.2257873", "pmid": "37729083", "labels": [], "xrefs": [], "notes": [], "created": "2026-09-23T13:35:33.758Z", "modified": "2026-09-23T13:35:33.861Z"}]}