{"entity": "researcher", "timestamp": "2026-08-20T21:11:29.317Z", "family": "Theorell-Hagl\u00f6w", "given": "Jenny", "initials": "J", "orcid": "0000-0003-2819-2799", "affiliations": ["Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.", "Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/bdbe4f0179eb46f890bbcc54805cf291.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/bdbe4f0179eb46f890bbcc54805cf291"}}, "publications": [{"entity": "publication", "iuid": "53dc2332a9ca4907bdcfdb318e887e97", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/53dc2332a9ca4907bdcfdb318e887e97.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/53dc2332a9ca4907bdcfdb318e887e97"}}, "title": "Obstructive sleep apnea is associated with specific gut microbiota species and functions in the population-based Swedish CardioPulmonary bioImage Study (SCAPIS)", "authors": [{"family": "Baldanzi", "given": "Gabriel", "initials": "G", "orcid": "0000-0003-3962-3953", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0f55bfbbb6304ebc91c13c1ddefa0c42.json"}}, {"family": "Sayols-Baixeras", "given": "Sergi", "initials": "S", "orcid": "0000-0002-1181-6262", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/13c5c3ffbe8f4ffda8cabbf2d0664906.json"}}, {"family": "Theorell-Hagl\u00f6w", "given": "Jenny", "initials": "J", "orcid": "0000-0003-2819-2799", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/bdbe4f0179eb46f890bbcc54805cf291.json"}}, {"family": "Dekkers", "given": "Koen F", "initials": "KF", "orcid": "0000-0002-4074-7235", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c290d03c7bbf457abdd06a151e3650fe.json"}}, {"family": "Hammar", "given": "Ulf", "initials": "U", "orcid": "0000-0001-8367-5000", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b833fa7c77f542aabd5b04f4d9c02afd.json"}}, {"family": "Nguyen", "given": "Diem", "initials": "D", "orcid": "0000-0002-9680-5772", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5b12f13041f343e19fd4566678181b69.json"}}, {"family": "Lin", "given": "Yi Ting", "initials": "YT", "orcid": "0000-0002-5833-0040", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/36368cfa632140839b84bc166dd09b1a.json"}}, {"family": "Ahmad", "given": "Shafqat", "initials": "S", "orcid": "0000-0002-1914-5248", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/edbc11d091084a2392a8dfc062f070e8.json"}}, {"family": "Holm", "given": "Jacob Bak", "initials": "JB", "orcid": "0000-0003-1756-0875", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/27bea3fb86174b0da08cbaf68820ae98.json"}}, {"family": "Nielsen", "given": "Henrik Bj\u00f8rn", "initials": "HB", "orcid": "0000-0003-2281-5713", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f42a7caf34014b1186783a3662375dd0.json"}}, {"family": "Brunkwall", "given": "Louise", "initials": "L"}, {"family": "Benedict", "given": "Christian", "initials": "C", "orcid": "0000-0002-8911-4068", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4754abd3a35249109dfe62d79808cf23.json"}}, {"family": "Cedernaes", "given": "Jonathan", "initials": "J", "orcid": "0000-0002-9052-8372", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/af9c0c50c8dc475daf410655475ea64d.json"}}, {"family": "Koskiniemi", "given": "Sanna", "initials": "S", "orcid": "0000-0002-3275-0936", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/cd05acc7311e433abf784f6e96841941.json"}}, {"family": "Phillipson", "given": "Mia", "initials": "M", "orcid": "0000-0002-2387-0266", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/265c9b3e11de4fcaa270a0eb20faf65c.json"}}, {"family": "Lind", "given": "Lars", "initials": "L", "orcid": "0000-0003-2335-8542", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/bb72ba22274c49dfb8a1cc5f607b1cdf.json"}}, {"family": "Sundstr\u00f6m", "given": "Johan", "initials": "J", "orcid": "0000-0003-2247-8454", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/2e1b8ae02d2949acaa8c2e18349b33a1.json"}}, {"family": "Bergstr\u00f6m", "given": "G\u00f6ran", "initials": "G", "orcid": "0000-0003-4289-5722", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d414b3352a4540a68227ca7eec73cfa6.json"}}, {"family": "Engstr\u00f6m", "given": "Gunnar", "initials": "G", "orcid": "0000-0002-8618-9152", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5faed1571d4742588095acc83e631dfc.json"}}, {"family": "Smith", "given": "J Gustav", "initials": "JG", "orcid": "0000-0001-6285-9935", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/98819c1b9e814b4388cfadc32b1f4e73.json"}}, {"family": "Orho-Melander", "given": "Marju", "initials": "M", "orcid": "0000-0002-3578-2503", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/09f3f572ea914566930761d3dcf189b0.json"}}, {"family": "\u00c4rnl\u00f6v", "given": "Johan", "initials": "J", "orcid": "0000-0002-6933-4637", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/292b3ce479bf480487f49dc793084f22.json"}}, {"family": "Kennedy", "given": "Beatrice", "initials": "B", "orcid": "0000-0002-0066-4814", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/cb88fcd6bead49978b129dffe779d8a0.json"}}, {"family": "Lindberg", "given": "Eva", "initials": "E", "orcid": "0000-0002-8552-4510", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/6fc99a1fb25c4bd98a45beb18e300aa2.json"}}, {"family": "Fall", "given": "Tove", "initials": "T", "orcid": "0000-0003-2071-5866", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7dbbd468e6da4727b69333ade942c071.json"}}], "type": "posted-content", "published": "2022-06-14", "journal": {"issn-l": null}, "abstract": null, "doi": "10.1101/2022.06.10.22276241", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T10:11:44.910Z", "modified": "2026-08-20T10:11:45.181Z"}, {"entity": "publication", "iuid": "3255bdad045e4a328bad0e00eadf8d3d", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/3255bdad045e4a328bad0e00eadf8d3d.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/3255bdad045e4a328bad0e00eadf8d3d"}}, "title": "Evening chronotype is associated with elevated biomarkers of cardiometabolic risk in the EpiHealth cohort: a cross-sectional study.", "authors": [{"family": "Baldanzi", "given": "Gabriel", "initials": "G", "orcid": "0000-0003-3962-3953", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0f55bfbbb6304ebc91c13c1ddefa0c42.json"}}, {"family": "Hammar", "given": "Ulf", "initials": "U"}, {"family": "Fall", "given": "Tove", "initials": "T"}, {"family": "Lindberg", "given": "Eva", "initials": "E"}, {"family": "Lind", "given": "Lars", "initials": "L", "orcid": "0000-0003-2335-8542", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/bb72ba22274c49dfb8a1cc5f607b1cdf.json"}}, {"family": "Elmst\u00e5hl", "given": "S\u00f6lve", "initials": "S"}, {"family": "Theorell-Hagl\u00f6w", "given": "Jenny", "initials": "J", "orcid": "0000-0003-2819-2799", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/bdbe4f0179eb46f890bbcc54805cf291.json"}}], "type": "journal article", "published": "2022-02-14", "journal": {"title": "Sleep", "issn": "1550-9109", "volume": "45", "issue": "2", "issn-l": "0161-8105"}, "abstract": "Individuals with evening chronotype have a higher risk of cardiovascular and metabolic disorders, although the underlying mechanisms are not well understood. In a population-based cohort, we aimed to investigate the association between chronotype and 242 circulating proteins from three panels of established or candidate biomarkers of cardiometabolic processes.\n\nIn 2,471 participants (49.7% men, mean age 61.2 \u00b1 8.4 SD years) from the EpiHealth cohort, circulating proteins were analyzed with a multiplex proximity extension technique. Participants self-reported their chronotype on a five-level scale from extreme morning to extreme evening chronotype. With the intermediate chronotype set as the reference, each protein was added as the dependent variable in a series of linear regression models adjusted for confounders. Next, the chronotype coefficients were jointly tested and the resulting p-values adjusted for multiple testing using a false discovery rate (5%). For the associations identified, we then analyzed the marginal effect of each chronotype category.\n\nWe identified 17 proteins associated with chronotype. Evening chronotype was positively associated with proteins previously linked to insulin resistance and cardiovascular risk, namely retinoic acid receptor protein 2, fatty acid-binding protein adipocyte, tissue-type plasminogen activator, and plasminogen activator inhibitor 1 (PAI-1). Additionally, PAI-1 was inversely associated with the extreme morning chronotype.\n\nIn this population-based study, proteins previously related to cardiometabolic risk were elevated in the evening chronotypes. These results may guide future research in the relation between chronotype and cardiometabolic disorders.", "doi": "10.1093/sleep/zsab226", "pmid": "34480568", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC8842133"}, {"db": "pii", "key": "6364133"}], "notes": [], "created": "2026-08-20T09:51:48.464Z", "modified": "2026-08-20T09:51:48.577Z"}]}