{"entity": "researcher", "timestamp": "2026-08-20T20:47:30.325Z", "family": "Dharamshi", "given": "Jennah E", "initials": "JE", "orcid": "0000-0003-4563-3939", "affiliations": ["Department of Ecology, Environment and Plant Sciences, Science for Life Laboratory, Stockholm University, Stockholm, Sweden.", "Department of Organismal Biology, Program in Systematic Biology, Uppsala University, Uppsala, Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/b742e97795a94ac99217930b27640e3a.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/b742e97795a94ac99217930b27640e3a"}}, "publications": [{"entity": "publication", "iuid": "5d48b1610c6d4a5eba9792f3c7d000ea", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/5d48b1610c6d4a5eba9792f3c7d000ea.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/5d48b1610c6d4a5eba9792f3c7d000ea"}}, "title": "Widespread potential for phototrophy and convergent reduction of lifecycle complexity in the dimorphic order Caulobacterales.", "authors": [{"family": "Hallgren", "given": "Joel", "initials": "J", "orcid": "0000-0001-8602-8095", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5abe8d6567cc4364b978078308aae0a9.json"}}, {"family": "Dharamshi", "given": "Jennah E", "initials": "JE", "orcid": "0000-0003-4563-3939", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b742e97795a94ac99217930b27640e3a.json"}}, {"family": "Rodr\u00edguez-Gij\u00f3n", "given": "Alejandro", "initials": "A"}, {"family": "Nuy", "given": "Julia", "initials": "J", "orcid": "0000-0003-0270-0070", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/97b276848fb74df19614617e2208351e.json"}}, {"family": "Garcia", "given": "Sarahi L", "initials": "SL", "orcid": "0000-0002-8622-0308", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/df5f980a4dfb4b669961af28a1242f12.json"}}, {"family": "Jonas", "given": "Kristina", "initials": "K", "orcid": "0000-0002-1469-4424", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d80edc12f0c841f2be1318449531d9ef.json"}}], "type": "journal article", "published": "2025-12-12", "journal": {"title": "Nat Commun", "issn": "2041-1723", "volume": "16", "issue": "1", "pages": "11003", "issn-l": "2041-1723"}, "abstract": "Model bacteria are fundamental for research, but knowledge about their ecology and evolution is often limited. Here, we establish an evolutionary and ecological context for the model organism Caulobacter crescentus-an alphaproteobacterium intensively studied for its dimorphic lifecycle. By analyzing the phylogenetic relatedness and genetic potential of hundreds of Caulobacterales species, we reveal substantial diversity regarding their environmental distribution, morphology, cell development, and metabolism. Our work provides insights into the evolutionary history of morphological features such as the cell curvature determinant crescentin and uncovers a striking case of convergent loss of traits for cellular dimorphism among close relatives of C. crescentus. Moreover, we find that genes for phototrophy are widespread across Caulobacterales and that the new genus Acaudatibacter, described here, includes the first reported Caulobacterales lineage with photoautotrophic potential. Our study advances our understanding of an environmentally widespread bacterial order and sheds light on the evolution of fundamental prokaryotic features.", "doi": "10.1038/s41467-025-65642-x", "pmid": "41387397", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC12700997"}, {"db": "pii", "key": "10.1038/s41467-025-65642-x"}], "notes": [], "created": "2026-08-20T08:54:18.360Z", "modified": "2026-08-20T08:54:18.523Z"}, {"entity": "publication", "iuid": "849d8580b80e4131b99bc8fecd8ffbe4", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/849d8580b80e4131b99bc8fecd8ffbe4.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/849d8580b80e4131b99bc8fecd8ffbe4"}}, "title": "Microbial model communities exhibit widespread metabolic interdependencies.", "authors": [{"family": "Pacheco-Valenciana", "given": "Armando", "initials": "A", "orcid": "0009-0009-2801-0917", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4dfa9503682c4b94abb1a5fe1da93ff8.json"}}, {"family": "Tausch", "given": "Anna", "initials": "A"}, {"family": "Veseli", "given": "Iva", "initials": "I"}, {"family": "Dharamshi", "given": "Jennah E", "initials": "JE", "orcid": "0000-0003-4563-3939", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b742e97795a94ac99217930b27640e3a.json"}}, {"family": "Bergland", "given": "Fabian", "initials": "F"}, {"family": "Delgado", "given": "Luis F", "initials": "LF"}, {"family": "Rodr\u00edguez-Gij\u00f3n", "given": "Alejandro", "initials": "A"}, {"family": "Andersson", "given": "Anders F", "initials": "AF", "orcid": "0000-0002-3627-6899", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/cc9be99ec6ca47ed8a805ebb4db7c168.json"}}, {"family": "Garcia", "given": "Sarahi L", "initials": "SL", "orcid": "0000-0002-8622-0308", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/df5f980a4dfb4b669961af28a1242f12.json"}}], "type": "journal article", "published": "2025-12-03", "journal": {"title": "Commun Biol", "issn": "2399-3642", "volume": "8", "issue": "1", "pages": "1752", "issn-l": "2399-3642"}, "abstract": "Microorganisms thrive in complex communities shaped by intricate interactions, yet the extent and ecological implications of biosynthetic dependencies in natural communities remain underexplored. Here, we used a dilution approach to cultivate 204 microbial model communities from the Baltic Sea and recovered 527 metagenome-assembled genomes (MAGs) that dereplicated into 72 species-clusters (>95% average nucleotide identity, ANI). Of these species, at least 70% represent previously uncultivated lineages. Combined with 1073 MAGs from Baltic Sea metagenomes, we generated a genomic catalog of 701 species-clusters. Our results show that cultures with more than three species included microorganisms with smaller genome sizes, lower biosynthetic potential for amino acids and B vitamins, and higher prevalence and abundance in the environment. Moreover, the taxa found together in the same model communities had complementary biosynthetic gene repertoires. Our results demonstrate that cultivating bacteria in dilution model communities facilitates access to previously uncultivated but abundant species that likely depend on metabolic partners for survival. Together, our findings highlight the value of community-based cultivation for unraveling ecological strategies. Finally, we confirm that metabolic interdependencies and genome streamlining are widespread features of successful environmental microorganisms.", "doi": "10.1038/s42003-025-09306-y", "pmid": "41339710", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC12680743"}, {"db": "pii", "key": "10.1038/s42003-025-09306-y"}], "notes": [], "created": "2026-08-20T09:25:28.462Z", "modified": "2026-08-20T09:25:28.582Z"}, {"entity": "publication", "iuid": "9c9cc903e1254751b73a8a35b683e3d0", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/9c9cc903e1254751b73a8a35b683e3d0.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/9c9cc903e1254751b73a8a35b683e3d0"}}, "title": "Widespread potential for phototrophy and convergent reduction of lifecycle complexity in the dimorphic order Caulobacterales", "authors": [{"family": "Hallgren", "given": "Joel", "initials": "J", "orcid": "0000-0001-8602-8095", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5abe8d6567cc4364b978078308aae0a9.json"}}, {"family": "Dharamshi", "given": "Jennah E", "initials": "JE", "orcid": "0000-0003-4563-3939", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b742e97795a94ac99217930b27640e3a.json"}}, {"family": "Rodr\u00edguez-Gij\u00f3n", "given": "Alejandro", "initials": "A", "orcid": "0000-0002-1649-6894", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7e5f654c25644bb5b306ead087dc55ae.json"}}, {"family": "Nuy", "given": "Julia", "initials": "J", "orcid": "0000-0003-0270-0070", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/97b276848fb74df19614617e2208351e.json"}}, {"family": "Garcia", "given": "Sarahi L", "initials": "SL", "orcid": "0000-0002-8622-0308", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/df5f980a4dfb4b669961af28a1242f12.json"}}, {"family": "Jonas", "given": "Kristina", "initials": "K", "orcid": "0000-0002-1469-4424", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d80edc12f0c841f2be1318449531d9ef.json"}}], "type": "posted-content", "published": "2025-05-26", "journal": {"issn-l": null}, "abstract": null, "doi": "10.1101/2025.05.26.656076", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T11:05:56.628Z", "modified": "2026-08-20T11:05:56.691Z"}, {"entity": "publication", "iuid": "473847fc145042cab255fe0c1add9423", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/473847fc145042cab255fe0c1add9423.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/473847fc145042cab255fe0c1add9423"}}, "title": "Low anabolic independence emerges when cultivating more than three bacterial species together", "authors": [{"family": "Pacheco-Valenciana", "given": "Armando", "initials": "A", "orcid": "0009-0009-2801-0917", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4dfa9503682c4b94abb1a5fe1da93ff8.json"}}, {"family": "Tausch", "given": "Anna", "initials": "A"}, {"family": "Veseli", "given": "Iva", "initials": "I", "orcid": "0000-0003-2390-5286", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/36dcb9c35b9c409babe1b0fccdb2435d.json"}}, {"family": "Dharamshi", "given": "Jennah E", "initials": "JE", "orcid": "0000-0003-4563-3939", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b742e97795a94ac99217930b27640e3a.json"}}, {"family": "Bergland", "given": "Fabian", "initials": "F"}, {"family": "Delgado Zambrano", "given": "Luis Fernando", "initials": "LF"}, {"family": "Rodr\u00edguez-Gij\u00f3n", "given": "Alejandro", "initials": "A", "orcid": "0000-0002-1649-6894", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7e5f654c25644bb5b306ead087dc55ae.json"}}, {"family": "Andersson", "given": "Anders F", "initials": "AF", "orcid": "0000-0002-3627-6899", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/cc9be99ec6ca47ed8a805ebb4db7c168.json"}}, {"family": "Garcia", "given": "Sarahi L", "initials": "SL", "orcid": "0000-0002-8622-0308", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/df5f980a4dfb4b669961af28a1242f12.json"}}], "type": "posted-content", "published": "2025-04-28", "journal": {"issn-l": null}, "abstract": null, "doi": "10.1101/2025.04.28.650956", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T11:02:32.174Z", "modified": "2026-08-20T11:02:32.275Z"}, {"entity": "publication", "iuid": "c8f46e1c090a477882811bdc5543949a", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/c8f46e1c090a477882811bdc5543949a.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/c8f46e1c090a477882811bdc5543949a"}}, "title": "Chlamydial contribution to anaerobic metabolism during eukaryotic evolution.", "authors": [{"family": "Stairs", "given": "Courtney W", "initials": "CW", "orcid": "0000-0001-6650-0970", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ed32f30aa29e4279aef72aed502d2a95.json"}}, {"family": "Dharamshi", "given": "Jennah E", "initials": "JE", "orcid": "0000-0003-4563-3939", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b742e97795a94ac99217930b27640e3a.json"}}, {"family": "Tamarit", "given": "Daniel", "initials": "D", "orcid": "0000-0002-4940-719X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1bc6a5827d7147e097a520745682be8c.json"}}, {"family": "Eme", "given": "Laura", "initials": "L", "orcid": "0000-0002-0510-8868", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/bcca924f04e04ac3a760c09c432064df.json"}}, {"family": "J\u00f8rgensen", "given": "Steffen L", "initials": "SL", "orcid": "0000-0003-0240-7907", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5e230b212e5248099306b14bc3cedd82.json"}}, {"family": "Spang", "given": "Anja", "initials": "A", "orcid": "0000-0002-6518-8556", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ee19a6765cb847caac5c440aeb15b509.json"}}, {"family": "Ettema", "given": "Thijs J G", "initials": "TJG", "orcid": "0000-0002-6898-6377", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/6a7921cec2bb45a7a7b0454f41b5f1aa.json"}}], "type": "journal article", "published": "2020-08-00", "journal": {"title": "Sci Adv", "issn": "2375-2548", "volume": "6", "issue": "35", "pages": "eabb7258", "issn-l": "2375-2548"}, "abstract": "The origin of eukaryotes is a major open question in evolutionary biology. Multiple hypotheses posit that eukaryotes likely evolved from a syntrophic relationship between an archaeon and an alphaproteobacterium based on H2 exchange. However, there are no strong indications that modern eukaryotic H2 metabolism originated from archaea or alphaproteobacteria. Here, we present evidence for the origin of H2 metabolism genes in eukaryotes from an ancestor of the Anoxychlamydiales-a group of anaerobic chlamydiae, newly described here, from marine sediments. Among Chlamydiae, these bacteria uniquely encode genes for H2 metabolism and other anaerobiosis-associated pathways. Phylogenetic analyses of several components of H2 metabolism reveal that Anoxychlamydiales homologs are the closest relatives to eukaryotic sequences. We propose that an ancestor of the Anoxychlamydiales contributed these key genes during the evolution of eukaryotes, supporting a mosaic evolutionary origin of eukaryotic metabolism.", "doi": "10.1126/sciadv.abb7258", "pmid": "32923644", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC7449678"}, {"db": "pii", "key": "abb7258"}, {"db": "figshare", "key": "10.6084/m9.figshare.12387980"}], "notes": [], "created": "2026-08-20T11:58:33.078Z", "modified": "2026-08-20T11:58:33.306Z"}]}