{"entity": "researcher", "timestamp": "2026-09-23T22:14:58.960Z", "family": "Panchaud", "given": "Alice", "initials": "A", "orcid": "0000-0001-6086-2401", "affiliations": ["Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.", "Service of Pharmacy, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/abd99a5f06aa401a86e0c14de367c914.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/abd99a5f06aa401a86e0c14de367c914"}}, "publications": [{"entity": "publication", "iuid": "bba7632240c546a7a007346eb6498360", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/bba7632240c546a7a007346eb6498360.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/bba7632240c546a7a007346eb6498360"}}, "title": "Medications Used Among Nonhospitalized Pregnant Women With COVID-19: A Prospective Individual Patient Data Meta-Analysis in Europe and North America.", "authors": [{"family": "de Bruin", "given": "Odette", "initials": "O", "orcid": "0000-0001-6295-3411", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/911b45cf22ce454cbd479115c0e9a977.json"}}, {"family": "Maisonneuve", "given": "Emeline", "initials": "E", "orcid": "0000-0001-5765-4468", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5bc34a21a3ac4d2697742e3e797f2c8c.json"}}, {"family": "Hurley", "given": "Eimir", "initials": "E", "orcid": "0000-0001-6776-1224", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/63d83f6bbc844b73ac52cf4a188a1b77.json"}}, {"family": "Nordeng", "given": "Hedvig M E", "initials": "HME", "orcid": "0000-0001-6361-2918", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/e149ec4deccc4c02a3d77948d4a3355d.json"}}, {"family": "B\u00e9rard", "given": "Anick", "initials": "A", "orcid": "0000-0001-7535-5517", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/945643632770419fb139cd993c07305d.json"}}, {"family": "Sheehy", "given": "Odile", "initials": "O", "orcid": "0000-0002-6784-2080", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7dcc3a2109bd4d0fb3773ca84bb17eb2.json"}}, {"family": "Kaul", "given": "Padma", "initials": "P", "orcid": "0000-0003-2239-3944", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0042e499f7b24cb794e2d7ee22286eab.json"}}, {"family": "Shinde", "given": "Mayura U", "initials": "MU"}, {"family": "Cosgrove", "given": "Austin", "initials": "A"}, {"family": "Lyons", "given": "Jennifer G", "initials": "JG"}, {"family": "Messenger-Jones", "given": "Elizabeth", "initials": "E"}, {"family": "Kempner", "given": "Maria E", "initials": "ME"}, {"family": "Toh", "given": "Sengwee", "initials": "S"}, {"family": "Hua", "given": "Wei", "initials": "W"}, {"family": "Hern\u00e1ndez-Mu\u00f1oz", "given": "Jos\u00e9 J", "initials": "JJ", "orcid": "0000-0002-2553-3159", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/617e214e65ab41b18b8b27c0e7ad2b2d.json"}}, {"family": "Sahin", "given": "Leyla", "initials": "L", "orcid": "0000-0002-7685-7524", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b2ce6da32e354740a5a2ee9f9848195c.json"}}, {"family": "Cesta", "given": "Carolyn E", "initials": "CE", "orcid": "0000-0001-5759-9366", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/35e1b896082549c2b69ead371bf4e3a8.json"}}, {"family": "H\u00e4gg", "given": "David", "initials": "D", "orcid": "0000-0002-2610-5033", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/cc4f13f046ee49f39b92677eaaa41e79.json"}}, {"family": "Gini", "given": "Rosa", "initials": "R", "orcid": "0000-0002-6250-877X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/10b66693cdc04e80ac5450f2e63a6d92.json"}}, {"family": "Paoletti", "given": "Olga", "initials": "O"}, {"family": "Poblador-Plou", "given": "Beatriz", "initials": "B"}, {"family": "Jordan", "given": "Sue", "initials": "S"}, {"family": "Thayer", "given": "Daniel", "initials": "D"}, {"family": "Rodr\u00edguez-Bernal", "given": "Clara L", "initials": "CL", "orcid": "0000-0003-2617-8635", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/812191eadd56405789ddb971577c4d6e.json"}}, {"family": "S\u00e1nchez-S\u00e1ez", "given": "Francisco", "initials": "F"}, {"family": "Lassalle", "given": "R\u00e9gis", "initials": "R"}, {"family": "Bernard", "given": "Marie-Agn\u00e8s", "initials": "MA"}, {"family": "Alsina", "given": "Ema", "initials": "E"}, {"family": "Ahmadizar", "given": "Fariba", "initials": "F"}, {"family": "Favre", "given": "Guillaume", "initials": "G", "orcid": "0000-0001-6181-3126", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/43764a2eb9544b559c88b0ab425bb9ad.json"}}, {"family": "Panchaud", "given": "Alice", "initials": "A", "orcid": "0000-0001-6086-2401", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/abd99a5f06aa401a86e0c14de367c914.json"}}, {"family": "Bloemenkamp", "given": "Kitty W M", "initials": "KWM", "orcid": "0000-0002-1377-4625", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9d38c9f319f442be810979223a78883c.json"}}, {"family": "Plueschke", "given": "Kelly", "initials": "K"}, {"family": "de Vries", "given": "Corinne", "initials": "C"}, {"family": "Siiskonen", "given": "Satu J", "initials": "SJ", "orcid": "0000-0003-3095-9530", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/effb583f45be406190adc4db3d0ee036.json"}}, {"family": "Sturkenboom", "given": "Miriam C J M", "initials": "MCJM", "orcid": "0000-0003-1360-2388", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4ac7233f5331454b9215810cbc940939.json"}}, {"family": "CONSIGN Collaboration Group", "given": "", "initials": ""}], "type": "journal article", "published": "2026-01-00", "journal": {"title": "Pharmacoepidemiol Drug Saf", "issn": "1099-1557", "volume": "35", "issue": "1", "pages": "e70303", "issn-l": null}, "abstract": "To estimate the prevalence of medication use in nonhospitalized pregnant women with COVID-19.\n\nA prospective two-stage individual patient meta-analysis across 10 data sources in Europe and North America studied medication use among nonhospitalized pregnant women with COVID-19 between January 2020 and December 2022. Comparisons were made between medication use within 30 days pre- and post-COVID-19 diagnosis in this cohort and two comparator groups: pregnant women without COVID-19 and nonpregnant women with COVID-19. Prevalence estimates were pooled using a random-effects model stratified by trimester.\n\n50 335 nonhospitalized pregnant women with COVID-19 were identified. The pooled prevalence of antibacterial use in the third trimester was higher post-COVID-19 diagnosis (6.8%, 95% confidence interval [CI] = 5.5-8.4, I2 = 94%) compared with the same women pre-COVID-19 (3.9%, 95% CI = 3.1-4.9, I2 = 89%). Overall, pregnant women with COVID-19 had higher medication use compared to pregnant women without COVID-19, although the CIs of the prevalence overlapped. Post-COVID-19, antithrombotic prevalence was 4.5% (95% CI = 1.1-16.5, I2 = 100%) among pregnant women with COVID-19 in the third trimester, compared to 2.1% (95% CI = 1.2-3.6, I2 = 99%) among those without COVID-19 in the third trimester. Compared to nonpregnant women with COVID-19, pregnant women with COVID-19 were less likely to be prescribed analgesics, antiprotozoals, corticosteroids, psychoanaleptics and psycholeptics, and more likely to be prescribed antithrombotics, cough and cold and nasal preparations, and drugs used in diabetes across all trimesters. High heterogeneity existed in nearly all analyses.\n\nThis international meta-analysis reveals low medication use and country-specific variations, enhancing insight into the management of COVID-19 in nonhospitalized pregnant women. Higher antithrombotic use post-COVID-19 suggests prophylactic treatment in this population, but variation between countries emphasizes the challenges of combining multinational data.", "doi": "10.1002/pds.70303", "pmid": "41449787", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC12741507"}], "notes": [], "created": "2026-09-23T15:58:48.095Z", "modified": "2026-09-23T15:58:48.684Z"}, {"entity": "publication", "iuid": "8923e25544c44ed9993b5b5c8954e17f", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/8923e25544c44ed9993b5b5c8954e17f.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/8923e25544c44ed9993b5b5c8954e17f"}}, "title": "Transfer of cetirizine/levocetirizine into human breast milk and estimation of drug exposure to infants through breastfeeding: A human lactation study from the ConcePTION project.", "authors": [{"family": "Nordeng", "given": "Hedvig", "initials": "H", "orcid": "0000-0001-6361-2918", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/e149ec4deccc4c02a3d77948d4a3355d.json"}}, {"family": "Wegler", "given": "Christine", "initials": "C", "orcid": "0000-0002-2810-7518", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/fcb45d19c52847f19bd5c0aa296afe10.json"}}, {"family": "Lindqvist", "given": "Annika", "initials": "A", "orcid": "0009-0003-2587-8434", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/89bd045cc7844e508c837da8a2887a22.json"}}, {"family": "Melander", "given": "Erik", "initials": "E", "orcid": "0009-0002-9981-3505", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8526de87b7914d7a9c62170c26fb9e4f.json"}}, {"family": "Magnusson", "given": "Mikaela", "initials": "M", "orcid": "0000-0003-4347-2094", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/eade0faf6b75494d84a4ad63d2799040.json"}}, {"family": "Gandia", "given": "Peggy", "initials": "P", "orcid": "0000-0002-4385-7894", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/6b66aba78159426ca9c50d348c962a3d.json"}}, {"family": "Panchaud", "given": "Alice", "initials": "A", "orcid": "0000-0001-6086-2401", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/abd99a5f06aa401a86e0c14de367c914.json"}}, {"family": "Baranczewski", "given": "Pawel", "initials": "P", "orcid": "0000-0001-5772-6791", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/327feae3833d425c9d5936f48627390c.json"}}, {"family": "Spigset", "given": "Olav", "initials": "O", "orcid": "0000-0001-7902-9014", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4029fefdca91491896e055abda57f25d.json"}}], "type": "journal article", "published": "2024-01-00", "journal": {"title": "Basic Clin. Pharmacol. Toxicol.", "issn": "1742-7843", "volume": "134", "issue": "1", "pages": "153-164", "issn-l": "1742-7835"}, "abstract": "Data on drug transfer into human breast milk are sparse. This study aimed to quantify concentrations of cetirizine and levocetirizine in breast milk and to estimate drug exposure to infants. Breastfeeding women at least 8 weeks postpartum and using cetirizine or its pure (R)-enantiomer levocetirizine were eligible to participate. Breast milk samples were collected at six predefined times during a dose interval (0, 2, 4, 8, 12 and 24 h after drug intake) at steady state. Infant drug exposure was estimated by calculating the absolute infant dose (AID) and the weight-adjusted relative infant dose (RID). In total, 32 women were eligible for final inclusion, 31 women using cetirizine and one woman using levocetirizine. Means of the individual maximum and average cetirizine milk concentrations were 41.0 and 16.8 \u03bcg/L, respectively. Maximum concentrations occurred on average 2.4 h after intake, and the mean half-life in milk was 7.0 h. Estimated AID and RID for cetirizine in a day were 2.5 \u03bcg/kg and 1.9%, respectively. The corresponding values for levocetirizine were 1.1 \u03bcg/kg and 1.9%. No severe adverse events were reported. Our findings demonstrate that the transfer of cetirizine and levocetirizine into breast milk is low and compatible with breastfeeding.", "doi": "10.1111/bcpt.13948", "pmid": "37811726", "labels": [], "xrefs": [], "notes": [], "created": "2026-09-23T12:10:11.915Z", "modified": "2026-09-23T12:10:12.195Z"}]}