{"entity": "researcher", "timestamp": "2026-08-20T20:30:36.582Z", "family": "Wiklund", "given": "Martin", "initials": "M", "orcid": "0000-0002-3247-1945", "affiliations": ["Department of Applied Physics, Science for Life Laboratory, KTH Royal Institute of Technology, SE-106 91 Stockholm, Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/a287459b32984379afc72c507bc44015.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/a287459b32984379afc72c507bc44015"}}, "publications": [{"entity": "publication", "iuid": "b92a2cc6e68c477a8f71cc65b1b2ab25", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/b92a2cc6e68c477a8f71cc65b1b2ab25.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/b92a2cc6e68c477a8f71cc65b1b2ab25"}}, "title": "EchoTilt: An Acoustofluidic Method for the Capture and Enrichment of Nanoplastics Directed Toward Drinking Water Monitoring.", "authors": [{"family": "Costa", "given": "Martim", "initials": "M", "orcid": "0000-0003-2675-9253", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f23b832326f446df963986a0266627c4.json"}}, {"family": "van der Geer", "given": "Liselotte", "initials": "L"}, {"family": "Joaquim", "given": "Miguel", "initials": "M"}, {"family": "Hammarstr\u00f6m", "given": "B", "initials": "B"}, {"family": "Tanriverdi", "given": "S", "initials": "S"}, {"family": "Joensson", "given": "H N", "initials": "HN"}, {"family": "Wiklund", "given": "M", "initials": "M", "orcid": "0000-0002-3247-1945", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/a287459b32984379afc72c507bc44015.json"}}, {"family": "Russom", "given": "A", "initials": "A", "orcid": "0000-0002-0242-358X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8939625551d5409aac4593329e2a6578.json"}}], "type": "journal article", "published": "2024-12-11", "journal": {"title": "Micromachines (Basel)", "issn": "2072-666X", "volume": "15", "issue": "12", "issn-l": "2072-666X"}, "abstract": "Micro- and nanoplastics have become increasingly relevant as contaminants to be monitored due to their potential health effects and environmental impact. Nanoplastics, in particular, have been shown to be difficult to detect in drinking water, requiring new capture technologies. In this work, we applied the acoustofluidic seed particle method to capture nanoplastics in an optimized, tilted grid of silica clusters even at the high flow rate of 5 mL/min. Moreover, we achieved, using this technique, the enrichment of nanoparticles ranging from 500 nm to 25 nm as a first in the field. We employed fluorescence to observe the enrichment profiles according to size, using a washing buffer flow at 0.5 mL/min, highlighting the size-dependent nature of the silica seed particle release of various sizes of nanoparticles. These results highlight the versatility of acoustic trapping for a wide range of nanoplastic particles and allow further study into the complex dynamics of the seed particle method at these size ranges. Moreover, with reproducible size-dependent washing curves, we provide a new window into the rate of nanoplastic escape in high-capacity acoustic traps, relevant to both environmental and biomedical applications.", "doi": "10.3390/mi15121487", "pmid": "39770240", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC11728305"}, {"db": "pii", "key": "mi15121487"}], "notes": [], "created": "2026-08-20T13:42:29.428Z", "modified": "2026-08-20T13:42:29.515Z"}, {"entity": "publication", "iuid": "a289ece2da0d4bf4ac8b3262b733a708", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/a289ece2da0d4bf4ac8b3262b733a708.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/a289ece2da0d4bf4ac8b3262b733a708"}}, "title": "Ultrasound-Based Scaffold-Free Core-Shell Multicellular Tumor Spheroid Formation.", "authors": [{"family": "Olofsson", "given": "Karl", "initials": "K", "orcid": "0000-0002-3976-3430", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0766218454224fc4902cb31f18455dc3.json"}}, {"family": "Carannante", "given": "Valentina", "initials": "V", "orcid": "0000-0003-4464-7087", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/e39f4c75a0c1476d846ff7b15a5b17c5.json"}}, {"family": "Takai", "given": "Madoka", "initials": "M", "orcid": "0000-0002-6238-6717", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/dfa9d1facf924a599e6ec3e9cbfa1b54.json"}}, {"family": "\u00d6nfelt", "given": "Bj\u00f6rn", "initials": "B"}, {"family": "Wiklund", "given": "Martin", "initials": "M", "orcid": "0000-0002-3247-1945", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/a287459b32984379afc72c507bc44015.json"}}], "type": "journal article", "published": "2021-03-20", "journal": {"title": "Micromachines (Basel)", "issn": "2072-666X", "volume": "12", "issue": "3", "issn-l": "2072-666X"}, "abstract": "In cancer research and drug screening, multicellular tumor spheroids (MCTSs) are a popular model to bridge the gap between in vitro and in vivo. However, the current techniques to culture mixed co-culture MCTSs do not mimic the structural architecture and cellular spatial distribution in solid tumors. In this study we present an acoustic trapping-based core-shell MCTSs culture method using sequential seeding of the core and shell cells into microwells coated with a protein repellent coating. Scaffold-free core-shell ovarian cancer OVCAR-8 cell line MCTSs were cultured, stained, cleared and confocally imaged on-chip. Image analysis techniques were used to quantify the shell thickness (23.2 \u00b1 1.8 \u00b5m) and shell coverage percentage (91.2 \u00b1 2.8%). We also show that the shell thickness was evenly distributed over the MCTS cores with the exception of being slightly thinner close to the microwell bottom. This scaffold-free core-shell MCTSs formation technique and the analysis tools presented herein could be used as an internal migration assay within the MCTS or to form core-shell MCTS co-cultures to study therapy response or the interaction between tumor and stromal cells.", "doi": "10.3390/mi12030329", "pmid": "33804708", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC8003921"}, {"db": "pii", "key": "mi12030329"}], "notes": [], "created": "2026-08-20T13:42:23.174Z", "modified": "2026-08-20T13:42:23.378Z"}]}