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[], "xrefs": [], "notes": [], "created": "2026-08-20T09:24:40.591Z", "modified": "2026-08-20T09:24:40.925Z"}, {"entity": "publication", "iuid": "15c41b274c4b41f0908aa1298dd5ac40", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/15c41b274c4b41f0908aa1298dd5ac40.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/15c41b274c4b41f0908aa1298dd5ac40"}}, "title": "Chemically Recyclable and Enzymatically Degradable Thermostable Polyesters with Inherent Strain from \u03b1-Pinene-Derived Chiral Diols", "authors": [{"family": "Ranjani", "given": "Ganapathy", "initials": "G", "orcid": "0000-0002-0191-4758", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/96cf27fbe1d342639e6a72fe3a6fb821.json"}}, {"family": "Subramaniyan", "given": "Sathiyaraj", "initials": "S", "orcid": "0000-0002-2477-6896", "researcher": {"href": 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Eng.", "issn": "2168-0485", "volume": "13", "issue": "18", "pages": "6696-6705", "issn-l": null}, "abstract": null, "doi": "10.1021/acssuschemeng.5c01374", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T08:13:51.974Z", "modified": "2026-08-20T08:45:41.146Z"}, {"entity": "publication", "iuid": "1fb121142bc844809f57c4726a2fd03a", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/1fb121142bc844809f57c4726a2fd03a.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/1fb121142bc844809f57c4726a2fd03a"}}, "title": "Fast Depolymerization of PET Bottle Mediated by Microwave Pre-Treatment and An Engineered PETase.", "authors": [{"family": "Guo", "given": "Boyang", "initials": "B", "orcid": "0000-0001-5510-1392", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/be843859e5a34c66b2c914c6f2bb955f.json"}}, {"family": "Lopez-Lorenzo", "given": "Ximena", "initials": "X", "orcid": "0000-0002-4708-9861", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/49eec96b36fd4880b09564c0b7688932.json"}}, {"family": "Fang", "given": "Yuan", "initials": "Y"}, {"family": "B\u00e4ckstr\u00f6m", "given": "Eva", "initials": "E"}, {"family": "Capezza", "given": "Antonio Jose", "initials": "AJ"}, {"family": "Vanga", "given": "Sudarsan Reddy", "initials": "SR"}, {"family": "Fur\u00f3", "given": "Istv\u00e1n", "initials": "I"}, {"family": "Hakkarainen", "given": "Minna", "initials": "M", "orcid": "0000-0002-7790-8987", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9d855814ea154871b096568c3e1d66a6.json"}}, {"family": "Syr\u00e9n", "given": "Per-Olof", "initials": "PO", "orcid": "0000-0002-4066-2776", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b035f26bd71e42f9942f9a4943ed0d1a.json"}}], "type": "journal article", "published": "2023-09-22", "journal": {"title": "ChemSusChem", "issn": "1864-564X", "volume": "16", "issue": "18", "pages": "e202300742", "issn-l": null}, "abstract": "Recycling plastics is the key to reaching a sustainable materials economy. Biocatalytic degradation of plastics shows great promise by allowing selective depolymerization of man-made materials into constituent building blocks under mild aqueous conditions. However, insoluble plastics have polymer chains that can reside in different conformations and show compact secondary structures that offer low accessibility for initiating the depolymerization reaction by enzymes. In this work, we overcome these shortcomings by microwave irradiation as a pre-treatment process to deliver powders of polyethylene terephthalate (PET) particles suitable for subsequent biotechnology-assisted plastic degradation by previously generated engineered enzymes. An optimized microwave step resulted in 1400 times higher integral of released terephthalic acid (TPA) from high-performance liquid chromatography (HPLC), compared to original untreated PET bottle. Biocatalytic plastic hydrolysis of substrates originating from PET bottles responded to 78 % yield conversion from 2 h microwave pretreatment and 1 h enzymatic reaction at 30 \u00b0C. The increase in activity stems from enhanced substrate accessibility from the microwave step, followed by the administration of designer enzymes capable of accommodating oligomers and shorter chains released in a productive conformation.", "doi": "10.1002/cssc.202300742", "pmid": "37384425", "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T06:31:57.604Z", "modified": "2026-08-20T06:31:57.734Z"}, {"entity": "publication", "iuid": "c7f0be383e3244a38fe4fa8c44712ccd", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/c7f0be383e3244a38fe4fa8c44712ccd.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/c7f0be383e3244a38fe4fa8c44712ccd"}}, "title": "Front Cover: Fast Depolymerization of PET Bottle Mediated by Microwave Pre\u2010Treatment and An Engineered PETase (ChemSusChem 18/2023)", "authors": [{"family": "Guo", "given": "Boyang", "initials": "B", "orcid": "0000-0001-5510-1392", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/be843859e5a34c66b2c914c6f2bb955f.json"}}, {"family": "Lopez\u2010Lorenzo", "given": "Ximena", "initials": "X", "orcid": "0000-0002-4708-9861", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/49eec96b36fd4880b09564c0b7688932.json"}}, {"family": "Fang", "given": "Yuan", "initials": "Y"}, {"family": "B\u00e4ckstr\u00f6m", "given": "Eva", "initials": "E"}, {"family": "Capezza", "given": "Antonio Jose", "initials": "AJ"}, {"family": "Vanga", "given": "Sudarsan Reddy", "initials": "SR"}, {"family": "Fur\u00f3", "given": "Istv\u00e1n", "initials": "I"}, {"family": "Hakkarainen", "given": "Minna", "initials": "M", "orcid": "0000-0002-7790-8987", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9d855814ea154871b096568c3e1d66a6.json"}}, {"family": "Syr\u00e9n", "given": "Per\u2010Olof", "initials": "P", "orcid": "0000-0002-4066-2776", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b035f26bd71e42f9942f9a4943ed0d1a.json"}}], "type": "journal-article", "published": "2023-09-22", "journal": {"title": "ChemSusChem", "issn": "1864-564X", "volume": "16", "issue": "18", "issn-l": null}, "abstract": null, "doi": "10.1002/cssc.202301238", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T06:32:06.636Z", "modified": "2026-08-20T06:32:06.715Z"}, {"entity": "publication", "iuid": "3da30a4e62cf4a5abf5e34759d377acc", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/3da30a4e62cf4a5abf5e34759d377acc.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/3da30a4e62cf4a5abf5e34759d377acc"}}, "title": "Whole\u2010cell Mediated Carboxylation of 2\u2010Furoic Acid Towards the Production of Renewable Platform Chemicals and Biomaterials", "authors": [{"family": "Lopez\u2010Lorenzo", "given": "Ximena", "initials": "X", "orcid": "0000-0002-4708-9861", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/49eec96b36fd4880b09564c0b7688932.json"}}, {"family": "Asem", "given": "Heba", "initials": "H"}, {"family": "Stamm", "given": "Arne", "initials": "A"}, {"family": "Subramaniyan", "given": "Sathiyaraj", "initials": "S"}, {"family": "Hakkarainen", "given": "Minna", "initials": "M", "orcid": "0000-0002-7790-8987", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9d855814ea154871b096568c3e1d66a6.json"}}, {"family": "Syr\u00e9n", "given": "Per\u2010Olof", "initials": "P", "orcid": "0000-0002-4066-2776", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b035f26bd71e42f9942f9a4943ed0d1a.json"}}], "type": "journal-article", "published": "2023-03-22", "journal": {"title": "ChemCatChem", "issn": "1867-3880", "volume": "15", "issue": "6", "issn-l": null}, "abstract": null, "doi": "10.1002/cctc.202201483", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T06:31:01.098Z", "modified": "2026-08-20T06:31:01.242Z"}, {"entity": "publication", "iuid": "70e45bb685d3420da66426080592cb6e", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/70e45bb685d3420da66426080592cb6e.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/70e45bb685d3420da66426080592cb6e"}}, "title": "Designed for Circularity: Chemically Recyclable and Enzymatically Degradable Biorenewable Schiff Base Polyester-Imines", "authors": [{"family": "Subramaniyan", "given": "Sathiyaraj", "initials": "S"}, {"family": "Najjarzadeh", "given": "Nasim", "initials": "N"}, {"family": "Vanga", "given": "Sudarsana Reddy", "initials": "SR"}, {"family": "Liguori", "given": "Anna", "initials": "A"}, {"family": "Syr\u00e9n", "given": "Per Olof", "initials": "PO", "orcid": "0000-0002-4066-2776", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b035f26bd71e42f9942f9a4943ed0d1a.json"}}, {"family": "Hakkarainen", "given": "Minna", "initials": "M", "orcid": "0000-0002-7790-8987", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9d855814ea154871b096568c3e1d66a6.json"}}], "type": "journal-article", "published": "2023-02-27", "journal": {"title": "ACS Sustainable Chem. Eng.", "issn": "2168-0485", "volume": "11", "issue": "8", "pages": "3451-3465", "issn-l": null}, "abstract": null, "doi": "10.1021/acssuschemeng.2c06935", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T08:13:50.034Z", "modified": "2026-08-20T08:45:39.129Z"}, {"entity": "publication", "iuid": "d6315b5e655a4a468d500d6692c69532", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/d6315b5e655a4a468d500d6692c69532.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/d6315b5e655a4a468d500d6692c69532"}}, "title": "Conformational Selection in Biocatalytic Plastic Degradation by PETase", "authors": [{"family": "Guo", "given": "Boyang", "initials": "B", "orcid": "0000-0001-5510-1392", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/be843859e5a34c66b2c914c6f2bb955f.json"}}, {"family": "Vanga", "given": "Sudarsana Reddy", "initials": "SR"}, {"family": "Lopez-Lorenzo", "given": "Ximena", "initials": "X"}, {"family": "Saenz-Mendez", "given": "Patricia", "initials": "P", "orcid": "0000-0002-6711-4972", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0efb9bc5eb7344bea1f44272fa4b2540.json"}}, {"family": "Ericsson", "given": "Sara R\u00f6nnblad", "initials": "SR"}, {"family": "Fang", "given": "Yuan", "initials": "Y"}, {"family": "Ye", "given": "Xinchen", "initials": "X"}, {"family": "Schriever", "given": "Karen", "initials": "K", "orcid": "0000-0002-3677-5508", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/282cce0f6c054fd8a7858977be549b24.json"}}, {"family": "B\u00e4ckstr\u00f6m", "given": "Eva", "initials": "E"}, {"family": "Biundo", "given": "Antonino", "initials": "A"}, {"family": "Zubarev", "given": "Roman A", "initials": "RA", "orcid": "0000-0001-9839-2089", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5e3f9910c1ff434c8056bdecf537e9ef.json"}}, {"family": "Fur\u00f3", "given": "Istv\u00e1n", "initials": "I", "orcid": "0000-0002-0231-3970", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8e47a4c36b86429e8b17845c02387f5d.json"}}, {"family": "Hakkarainen", "given": "Minna", "initials": "M", "orcid": "0000-0002-7790-8987", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9d855814ea154871b096568c3e1d66a6.json"}}, {"family": "Syr\u00e9n", "given": "Per Olof", "initials": "PO", "orcid": "0000-0002-4066-2776", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b035f26bd71e42f9942f9a4943ed0d1a.json"}}], "type": "journal-article", "published": "2022-03-18", "journal": {"title": "ACS Catal", "issn": "2155-5435", "volume": "12", "issue": "6", "pages": "3397-3409", "issn-l": "2155-5435"}, "abstract": null, "doi": "10.1021/acscatal.1c05548", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T08:09:01.454Z", "modified": "2026-08-20T08:09:01.681Z"}]}