{"entity": "researcher", "timestamp": "2026-07-22T17:45:36.810Z", "family": "Kocaba\u015f", "given": "P\u0131nar", "initials": "P", "orcid": "0000-0001-9788-2019", "affiliations": ["Department of Biology and Biological Engineering, Chalmers University of Technology, Kemiv\u00e4gen 10, SE-41258 Gothenburg, Sweden.", "Wallenberg Center for Protein Research, Chalmers University of Technology, Kemiv\u00e4gen 10, SE-41258 Gothenburg, Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/87f4b6d6a9b24100b74913dbe2441a64.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/87f4b6d6a9b24100b74913dbe2441a64"}}, "publications": [{"entity": "publication", "iuid": "29ee70e5750c4da7bccbbe44c1a968fb", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/29ee70e5750c4da7bccbbe44c1a968fb.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/29ee70e5750c4da7bccbbe44c1a968fb"}}, "title": "An atlas of human metabolism.", "authors": [{"family": "Robinson", "given": "Jonathan L", "initials": "JL", "orcid": "0000-0001-8567-5960", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/528edd3ba8374bdd8e3187556978c5ef.json"}}, {"family": "Kocaba\u015f", "given": "P\u0131nar", "initials": "P", "orcid": "0000-0001-9788-2019", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/87f4b6d6a9b24100b74913dbe2441a64.json"}}, {"family": "Wang", "given": "Hao", "initials": "H", "orcid": "0000-0001-7475-0136", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/77429d26b3884b328ef827033ff1e7b6.json"}}, {"family": "Cholley", "given": "Pierre-Etienne", "initials": "PE"}, {"family": "Cook", "given": "Daniel", "initials": "D", "orcid": "0000-0001-5534-8600", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ea66e464f79c40ddb214951d977e8812.json"}}, {"family": "Nilsson", "given": "Avlant", "initials": "A", "orcid": "0000-0002-9476-4516", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f2e21dbc1c624f6a841c59e959e948e4.json"}}, {"family": "Anton", "given": "Mihail", "initials": "M", "orcid": "0000-0002-7753-9042", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/733c89e6b386409392abf45608738222.json"}}, {"family": "Ferreira", "given": "Raphael", "initials": "R", "orcid": "0000-0001-9881-6232", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/e49665e6eabf40bd83ef8f573ff030ef.json"}}, {"family": "Domenzain", "given": "Iv\u00e1n", "initials": "I", "orcid": "0000-0002-5322-2040", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/588d2eed593448689fd63a7e656b5615.json"}}, {"family": "Billa", "given": "Virinchi", "initials": "V"}, {"family": "Limeta", "given": "Angelo", "initials": "A"}, {"family": "Hedin", "given": "Alex", "initials": "A", "orcid": "0000-0002-0829-2496", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7913daea4e3640fa9c2c00c631e23685.json"}}, {"family": "Gustafsson", "given": "Johan", "initials": "J", "orcid": "0000-0001-5072-2659", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/39eef1abb23c4ecab986fe0646830f07.json"}}, {"family": "Kerkhoven", "given": "Eduard J", "initials": "EJ", "orcid": "0000-0002-3593-5792", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/182c8731b6744479864cc75ced13d229.json"}}, {"family": "Svensson", "given": "L Thomas", "initials": "LT", "orcid": "0000-0002-9190-2979", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/540426d33d3b44d28cb823e6557dda36.json"}}, {"family": "Palsson", "given": "Bernhard O", "initials": "BO", "orcid": "0000-0003-2357-6785", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/fd602b497a2f48f39452f55f1fc28ac9.json"}}, {"family": "Mardinoglu", "given": "Adil", "initials": "A", "orcid": "0000-0002-4254-6090", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ca58bf2d214047e0ae5e38a42a0f2808.json"}}, {"family": "Hansson", "given": "Lena", "initials": "L"}, {"family": "Uhl\u00e9n", "given": "Mathias", "initials": "M", "orcid": "0000-0002-4858-8056", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9ea446aa574042a295d5f69437402f76.json"}}, {"family": "Nielsen", "given": "Jens", "initials": "J", "orcid": "0000-0002-9955-6003", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/33f2b49a39ed4e54ba77dfe397ed3087.json"}}], "type": "journal article", "published": "2020-03-24", "journal": {"title": "Sci Signal", "issn": "1937-9145", "issn-l": "1945-0877", "volume": "13", "issue": "624", "pages": "eaaz1482"}, "abstract": "Genome-scale metabolic models (GEMs) are valuable tools to study metabolism and provide a scaffold for the integrative analysis of omics data. Researchers have developed increasingly comprehensive human GEMs, but the disconnect among different model sources and versions impedes further progress. We therefore integrated and extensively curated the most recent human metabolic models to construct a consensus GEM, Human1. We demonstrated the versatility of Human1 through the generation and analysis of cell- and tissue-specific models using transcriptomic, proteomic, and kinetic data. We also present an accompanying web portal, Metabolic Atlas (https://www.metabolicatlas.org/), which facilitates further exploration and visualization of Human1 content. Human1 was created using a version-controlled, open-source model development framework to enable community-driven curation and refinement. This framework allows Human1 to be an evolving shared resource for future studies of human health and disease.", "doi": "10.1126/scisignal.aaz1482", "pmid": "32209698", "labels": {"Adil Mardinoglu": null, "SciLifeLab Fellow": null, "Avlant Nilsson": null}, "xrefs": [{"db": "mid", "key": "NIHMS1590510"}, {"db": "pmc", "key": "PMC7331181"}, {"db": "pii", "key": "13/624/eaaz1482"}], "notes": [], "created": "2020-11-30T03:10:14.353Z", "modified": "2025-03-20T11:10:02.058Z"}]}