{"entity": "researcher", "timestamp": "2026-08-23T22:11:54.246Z", "family": "Nordeman", "given": "Patrik", "initials": "P", "orcid": "0000-0002-4334-7368", "affiliations": ["Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/7bb9dad5c94f4ab19ebcc234b7c496b0.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/7bb9dad5c94f4ab19ebcc234b7c496b0"}}, "publications": [{"entity": "publication", "iuid": "e65f7a7fb31b4a0ab05c115c98224d4a", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/e65f7a7fb31b4a0ab05c115c98224d4a.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/e65f7a7fb31b4a0ab05c115c98224d4a"}}, "title": "Automated GMP-production of \u03b1-[11 C]methyl-L-tryptophan using a tracer production system (TPS).", "authors": [{"family": "Nordeman", "given": "Patrik", "initials": "P", "orcid": "0000-0002-4334-7368", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7bb9dad5c94f4ab19ebcc234b7c496b0.json"}}, {"family": "Yngve", "given": "Ulrika", "initials": "U"}, {"family": "Wilking", "given": "Helena", "initials": "H"}, {"family": "Gustavsson", "given": "Sven \u00c5ke", "initials": "S\u00c5"}, {"family": "Eriksson", "given": "Jonas", "initials": "J"}, {"family": "Antoni", "given": "Gunnar", "initials": "G"}], "type": "journal article", "published": "2018-12-00", "journal": {"title": "J Labelled Comp Radiopharm", "issn": "1099-1344", "volume": "61", "issue": "14", "pages": "1106-1109", "issn-l": "0362-4803"}, "abstract": "The radiosynthesis and GMP validation of [11 C]AMT for human use are described. Three consecutive batches were produced giving 940-3790 MBq (4%-17% RCY, decay corrected, based on [11 C]CO2 ) of the tracer. The molar activity at the end of synthesis was 19 to 35 GBq/\u03bcmol, the radiochemical purity was \u226598%, and the enantiomeric purity was >99%. While the synthesis method was automated using a new generation of synthesis equipment, tracer production system developed in house, the method should be readily applicable to other synthesis platforms with minor modifications.", "doi": "10.1002/jlcr.3648", "pmid": "29902836", "labels": [], "xrefs": [], "notes": [], "created": "2026-08-21T11:03:00.962Z", "modified": "2026-08-21T11:03:01.018Z"}]}