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"Jian", "initials": "J", "orcid": "0000-0002-6192-4632", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/375d2d10c6d84c15b8b304fe843e7485.json"}}, {"family": "Thomaidis", "given": "Nikolaos S", "initials": "NS", "orcid": "0000-0002-4624-4735", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9d3bbf9dbfdf463ab06ca2ca14b65c93.json"}}, {"family": "Hollender", "given": "Juliane", "initials": "J", "orcid": "0000-0002-4660-274X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3424c950c52e4c1bbdd3b91bb867961b.json"}}, {"family": "Slobodnik", "given": "Jaroslav", "initials": "J", "orcid": "0000-0003-2622-6318", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8978aea5862b4f5490b5f640d40a4b50.json"}}, {"family": "Schymanski", "given": "Emma L", "initials": "EL", "orcid": "0000-0001-6868-8145", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/cc533a4744624b80960f4cf28cabdd64.json"}}], "type": "journal article", "published": "2022-10-21", "journal": {"title": "Environ Sci Eur", "issn": "2190-4707", "volume": "34", "issue": "1", "pages": "104", "issn-l": null}, "abstract": "The NORMAN Association (https://www.norman-network.com/) initiated the NORMAN Suspect List Exchange (NORMAN-SLE; https://www.norman-network.com/nds/SLE/) in 2015, following the NORMAN collaborative trial on non-target screening of environmental water samples by mass spectrometry. Since then, this exchange of information on chemicals that are expected to occur in the environment, along with the accompanying expert knowledge and references, has become a valuable knowledge base for \"suspect screening\" lists. The NORMAN-SLE now serves as a FAIR (Findable, Accessible, Interoperable, Reusable) chemical information resource worldwide.\n\nThe NORMAN-SLE contains 99 separate suspect list collections (as of May 2022) from over 70 contributors around the world, totalling over 100,000 unique substances. The substance classes include per- and polyfluoroalkyl substances (PFAS), pharmaceuticals, pesticides, natural toxins, high production volume substances covered under the European REACH regulation (EC: 1272/2008), priority contaminants of emerging concern (CECs) and regulatory lists from NORMAN partners. Several lists focus on transformation products (TPs) and complex features detected in the environment with various levels of provenance and structural information. Each list is available for separate download. The merged, curated collection is also available as the NORMAN Substance Database (NORMAN SusDat). Both the NORMAN-SLE and NORMAN SusDat are integrated within the NORMAN Database System (NDS). The individual NORMAN-SLE lists receive digital object identifiers (DOIs) and traceable versioning via a Zenodo community (https://zenodo.org/communities/norman-sle), with a total of > 40,000 unique views, > 50,000 unique downloads and 40 citations (May 2022). NORMAN-SLE content is progressively integrated into large open chemical databases such as PubChem (https://pubchem.ncbi.nlm.nih.gov/) and the US EPA's CompTox Chemicals Dashboard (https://comptox.epa.gov/dashboard/), enabling further access to these lists, along with the additional functionality and calculated properties these resources offer. PubChem has also integrated significant annotation content from the NORMAN-SLE, including a classification browser (https://pubchem.ncbi.nlm.nih.gov/classification/#hid=101).\n\nThe NORMAN-SLE offers a specialized service for hosting suspect screening lists of relevance for the environmental community in an open, FAIR manner that allows integration with other major chemical resources. These efforts foster the exchange of information between scientists and regulators, supporting the paradigm shift to the \"one substance, one assessment\" approach. New submissions are welcome via the contacts provided on the NORMAN-SLE website (https://www.norman-network.com/nds/SLE/).\n\nThe online version contains supplementary material available at 10.1186/s12302-022-00680-6.", "doi": "10.1186/s12302-022-00680-6", "pmid": "36284750", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC9587084"}, {"db": "pii", "key": "680"}], "notes": [], "created": "2026-08-20T12:19:25.309Z", "modified": "2026-08-20T12:19:28.198Z"}, {"entity": "publication", "iuid": "38a3606a2dfa4c5d8f2558d2bb1f4944", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/38a3606a2dfa4c5d8f2558d2bb1f4944.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/38a3606a2dfa4c5d8f2558d2bb1f4944"}}, "title": "High-resolution mass spectrometry (HRMS) methods for nontarget discovery and characterization of poly- and per-fluoroalkyl substances (PFASs) in environmental and human samples", "authors": [{"family": "Liu", "given": "Yanna", "initials": "Y", "orcid": "0000-0001-7893-9876", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/734b3bae2f254a1e8252f573a60bebea.json"}}, {"family": "D'Agostino", "given": "Lisa A", "initials": "LA"}, {"family": "Qu", "given": "Guangbo", "initials": "G"}, {"family": "Jiang", "given": "Guibin", "initials": "G"}, {"family": "Martin", "given": "Jonathan W", "initials": "JW"}], "type": "journal-article", "published": "2019-12-00", "journal": {"title": "TrAC Trends in Analytical Chemistry", "issn": "0165-9936", "volume": "121", "pages": "115420", "issn-l": null}, "abstract": null, "doi": "10.1016/j.trac.2019.02.021", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T08:06:00.480Z", "modified": "2026-08-20T08:06:00.541Z"}, {"entity": "publication", "iuid": "368ce8fe9e9545949b523eaea5b214ee", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/368ce8fe9e9545949b523eaea5b214ee.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/368ce8fe9e9545949b523eaea5b214ee"}}, "title": "Hundreds of Unrecognized Halogenated Contaminants Discovered in Polar Bear Serum", "authors": [{"family": "Liu", "given": "Yanna", "initials": "Y", "orcid": "0000-0001-7893-9876", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/734b3bae2f254a1e8252f573a60bebea.json"}}, {"family": "Richardson", "given": "Evan S", "initials": "ES"}, {"family": "Derocher", "given": "Andrew E", "initials": "AE"}, {"family": "Lunn", "given": "Nicholas J", "initials": "NJ"}, {"family": "Lehmler", "given": "Hans\u2010Joachim", "initials": "H", "orcid": "0000-0001-9163-927X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/28d149985cb341158da7fa75d18bade2.json"}}, {"family": "Li", "given": "Xueshu", "initials": "X", "orcid": "0000-0002-0881-5381", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/124d6ec8cb8f4325bb8f1d935b2098a0.json"}}, {"family": "Zhang", "given": "Yifeng", "initials": "Y", "orcid": "0000-0002-6454-4918", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/53fa639d564c463490c9be07e6b171df.json"}}, {"family": "Cui", "given": "Julia Yue", "initials": "JY", "orcid": "0000-0002-8564-1784", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b058da26f0ac449f9b6d5c0a349da23b.json"}}, {"family": "Cheng", "given": "Lihua", "initials": "L"}, {"family": "Martin", "given": "Jonathan W", "initials": "JW", "orcid": "0000-0001-6265-4294", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/02199c0d99674e2ea5e96e6589c07a00.json"}}], "type": "journal-article", "published": "2018-12-10", "journal": {"title": "Angewandte Chemie", "issn": "0044-8249", "volume": "130", "issue": "50", "pages": "16639-16644", "issn-l": null}, "abstract": null, "doi": "10.1002/ange.201809906", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T06:29:30.745Z", "modified": "2026-08-20T06:29:30.971Z"}, {"entity": "publication", "iuid": "3b6b5d4ad3d040b6ab17c8e696615069", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/3b6b5d4ad3d040b6ab17c8e696615069.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/3b6b5d4ad3d040b6ab17c8e696615069"}}, "title": "Hundreds of Unrecognized Halogenated Contaminants Discovered in Polar Bear Serum.", "authors": [{"family": "Liu", "given": "Yanna", "initials": "Y", "orcid": "0000-0001-7893-9876", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/734b3bae2f254a1e8252f573a60bebea.json"}}, {"family": "Richardson", "given": "Evan S", "initials": "ES"}, {"family": "Derocher", "given": "Andrew E", "initials": "AE"}, {"family": "Lunn", "given": "Nicholas J", "initials": "NJ"}, {"family": "Lehmler", "given": "Hans-Joachim", "initials": "HJ", "orcid": "0000-0001-9163-927X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/28d149985cb341158da7fa75d18bade2.json"}}, {"family": "Li", "given": "Xueshu", "initials": "X", "orcid": "0000-0002-0881-5381", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/124d6ec8cb8f4325bb8f1d935b2098a0.json"}}, {"family": "Zhang", "given": "Yifeng", "initials": "Y", "orcid": "0000-0002-6454-4918", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/53fa639d564c463490c9be07e6b171df.json"}}, {"family": "Cui", "given": "Julia Yue", "initials": "JY", "orcid": "0000-0002-8564-1784", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b058da26f0ac449f9b6d5c0a349da23b.json"}}, {"family": "Cheng", "given": "Lihua", "initials": "L"}, {"family": "Martin", "given": "Jonathan W", "initials": "JW", "orcid": "0000-0001-6265-4294", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/02199c0d99674e2ea5e96e6589c07a00.json"}}], "type": "journal article", "published": "2018-12-10", "journal": {"title": "Angew. Chem. Int. Ed. Engl.", "issn": "1521-3773", "volume": "57", "issue": "50", "pages": "16401-16406", "issn-l": "1433-7851"}, "abstract": "Exposure of polar bears (Ursus maritimus) to persistent organic pollutants was discovered in the 1970s, but recent evidence suggests the presence of unknown toxic chemicals in their blood. Protein and phospholipid depleted serum was stirred with polyethersulfone capillaries to extract a broad range of analytes, and nontarget mass spectrometry with \"fragmentation flagging\" was used for detection. Hundreds of analytes were discovered belonging to 13 classes, including novel polychlorinated biphenyl (PCB) metabolites and many fluorinated or chlorinated substances not previously detected. All analytes were detected in the oldest (mid-1980s) archived polar bear serum from Hudson Bay and Beaufort Sea, and all fluorinated classes showed increasing trends. A mouse experiment confirmed the novel PCB metabolites, suggesting that these could be widespread in mammals. Historical exposure and toxic risk has been underestimated, and these halogenated contaminants pose uncertain risks to this threatened species.", "doi": "10.1002/anie.201809906", "pmid": "30376612", "labels": [], "xrefs": [{"db": "mid", "key": "NIHMS1006795"}, {"db": "pmc", "key": "PMC6394828"}], "notes": [], "created": "2026-08-20T06:29:53.820Z", "modified": "2026-08-20T06:29:53.906Z"}, {"entity": "publication", "iuid": "f7ff066ba81242ceb91f39591c6727dc", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/f7ff066ba81242ceb91f39591c6727dc.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/f7ff066ba81242ceb91f39591c6727dc"}}, "title": "Hundreds of Unrecognized Halogenated Contaminants Discovered in Polar Bear Blood", "authors": [{"family": "Liu", "given": "Yanna", "initials": "Y", "orcid": "0000-0001-7893-9876", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/734b3bae2f254a1e8252f573a60bebea.json"}}, {"family": "Richardson", "given": "Evan S", "initials": "ES"}, {"family": "Derocher", "given": "Andrew E", "initials": "AE"}, {"family": "Lunn", "given": "Nicholas J", "initials": "NJ"}, {"family": "Lehmler", "given": "Hans Joachim", "initials": "HJ"}, {"family": "Li", "given": "Xueshu", "initials": "X"}, {"family": "Zhang", "given": "Yifeng", "initials": "Y"}, {"family": "Yue Cui", "given": "Julia", "initials": "J"}, {"family": "Cheng", "given": "Lihua", "initials": "L"}, {"family": "Martin", "given": "Jonathan W", "initials": "JW"}], "type": "posted-content", "published": "2018-11-23", "journal": {"issn-l": null}, "abstract": null, "doi": "10.26434/chemrxiv.7332764.v1", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T13:03:35.618Z", "modified": "2026-08-20T13:03:37.368Z"}]}