{"entity": "researcher", "timestamp": "2026-08-25T13:39:47.404Z", "family": "Brandt", "given": "Peter", "initials": "P", "orcid": "0000-0002-2885-2016", "affiliations": ["Department of Medicinal Chemistry, Division of Organic Pharmaceutical Chemistry, BMC, Uppsala University , Box 574, SE-751 23, Uppsala, Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/69fda8874d1a44e6887492c17e4dea2a.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/69fda8874d1a44e6887492c17e4dea2a"}}, "publications": [{"entity": "publication", "iuid": "00b33e51e8304d0993fe14a80a628589", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/00b33e51e8304d0993fe14a80a628589.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/00b33e51e8304d0993fe14a80a628589"}}, "title": "Route to 3-Amidino Indoles via Pd(II)-Catalyzed C-H Bond Activation.", "authors": [{"family": "Rydfjord", "given": "Jonas", "initials": "J"}, {"family": "Skillinghaug", "given": "Bobo", "initials": "B"}, {"family": "Brandt", "given": "Peter", "initials": "P", "orcid": "0000-0002-2885-2016", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/69fda8874d1a44e6887492c17e4dea2a.json"}}, {"family": "Odell", "given": "Luke R", "initials": "LR", "orcid": "0000-0001-7658-5103", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/49395660c6af4fce9ad0f7f8fc793744.json"}}, {"family": "Larhed", "given": "Mats", "initials": "M", "orcid": "0000-0001-6258-0635", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/225695195abc4233bd141e6858e72e7f.json"}}], "type": "journal article", "published": "2017-08-04", "journal": {"title": "Org. Lett.", "issn": "1523-7052", "volume": "19", "issue": "15", "pages": "4066-4069", "issn-l": null}, "abstract": "We report a facile synthesis of 3-amidino indoles from indoles and cyanamides. The reaction is Pd(II)-catalyzed and proceeds via C-H bond activation of the indole in its 3-position followed by a 1,2-addition of the resulting indole-palladium \u03c3-complex to a cyanamide, which provides the corresponding amidine. The preference for 4,5-diazafluoren-9-one (DAF) as the ligand is investigated using DFT calculations, and a plausible reaction pathway is presented.", "doi": "10.1021/acs.orglett.7b01836", "pmid": "28741950", "labels": [], "xrefs": [], "notes": [], "created": "2018-12-05T12:09:56.699Z", "modified": "2026-08-21T11:34:42.188Z"}, {"entity": "publication", "iuid": "8f8eb67b5ce2468a8fe520b1ab99c55d", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/8f8eb67b5ce2468a8fe520b1ab99c55d.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/8f8eb67b5ce2468a8fe520b1ab99c55d"}}, "title": "Selective Synthesis of Spirooxindoles by an Intramolecular Heck-Mizoroki Reaction.", "authors": [{"family": "Roy", "given": "Tamal", "initials": "T"}, {"family": "Brandt", "given": "Peter", "initials": "P", "orcid": "0000-0002-2885-2016", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/69fda8874d1a44e6887492c17e4dea2a.json"}}, {"family": "Wetzel", "given": "Alexander", "initials": "A"}, {"family": "Bergman", "given": "Joakim", "initials": "J"}, {"family": "Br\u00e5nalt", "given": "Jonas", "initials": "J"}, {"family": "S\u00e4vmarker", "given": "Jonas", "initials": "J"}, {"family": "Larhed", "given": "Mats", "initials": "M", "orcid": "0000-0001-6258-0635", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/225695195abc4233bd141e6858e72e7f.json"}}], "type": "journal article", "published": "2017-05-19", "journal": {"title": "Org. Lett.", "issn": "1523-7052", "volume": "19", "issue": "10", "pages": "2738-2741", "issn-l": null}, "abstract": "We report a highly diastereoselective synthesis of cyclopentene-spirooxindole derivatives via an intramolecular Heck-Mizoroki reaction using aryl bromides as precursors. The reactions were performed under dry conditions or in a DMF-water system. This protocol can be useful to introduce several functionalities to the aromatic nucleus of the spirooxindoles. DFT calculations were performed to rationalize the high antiselectivity. A functionalized spiroproduct was transformed into a cyclic amino acid derivative.", "doi": "10.1021/acs.orglett.7b01094", "pmid": "28471686", "labels": [], "xrefs": [], "notes": [], "created": "2018-12-05T12:30:47.327Z", "modified": "2026-08-21T11:34:40.196Z"}, {"entity": "publication", "iuid": "094d199b9f00410e97a8d4ede99faf7d", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/094d199b9f00410e97a8d4ede99faf7d.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/094d199b9f00410e97a8d4ede99faf7d"}}, "title": "Regio- and Stereoselective Synthesis of Functionalized Cyclopentene Derivatives via Mizoroki-Heck Reactions.", "authors": [{"family": "Wetzel", "given": "Alexander", "initials": "A"}, {"family": "Bergman", "given": "Joakim", "initials": "J"}, {"family": "Brandt", "given": "Peter", "initials": "P", "orcid": "0000-0002-2885-2016", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/69fda8874d1a44e6887492c17e4dea2a.json"}}, {"family": "Larhed", "given": "Mats", "initials": "M", "orcid": "0000-0001-6258-0635", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/225695195abc4233bd141e6858e72e7f.json"}}, {"family": "Br\u00e5nalt", "given": "Jonas", "initials": "J"}], "type": "journal article", "published": "2017-04-07", "journal": {"volume": "19", "issn": "1523-7052", "issue": "7", "pages": "1602-1605", "title": "Org. Lett.", "issn-l": null}, "abstract": "Pd(0)-catalyzed Mizoroki-Heck alkenylations and arylations of protected aminocyclopentenes, prepared in a few steps from Vince lactam, afforded functionalized cyclopentenes in high yields and stereoselectivities. DFT calculations were performed to rationalize the high diastereoselectivities. Functionalized cyclopentene products were transformed into valuable chiral building blocks, such as cyclic \u03b3-amino acids and carbocyclic nucleoside precursors.", "doi": "10.1021/acs.orglett.7b00325", "pmid": "28290201", "labels": [], "xrefs": [], "notes": [], "created": "2018-12-05T11:42:45.814Z", "modified": "2026-08-21T11:34:38.132Z"}]}