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"display": {"href": "https://publications-affiliated.scilifelab.se/publication/77aafdc6221a4c30a2cf205ecf7406a4"}}, "title": "ELIXIR and Toxicology: a community in development.", "authors": [{"family": "Martens", "given": "Marvin", "initials": "M", "orcid": "0000-0003-2230-0840", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/40559d51100c4fa9ba76415bbf63e005.json"}}, {"family": "Stierum", "given": "Rob", "initials": "R"}, {"family": "Schymanski", "given": "Emma L", "initials": "EL", "orcid": "0000-0001-6868-8145", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/cc533a4744624b80960f4cf28cabdd64.json"}}, {"family": "Evelo", "given": "Chris T", "initials": "CT", "orcid": "0000-0002-5301-3142", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/94c28c62b88348bab934ab499ae3ccc2.json"}}, {"family": "Aalizadeh", "given": "Reza", "initials": "R"}, {"family": "Aladjov", "given": "Hristo", 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{"family": "Williams", "given": "Antony J", "initials": "AJ", "orcid": "0000-0002-2668-4821", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/11c7f6e4f5a646fab5020f2afcaed4ca.json"}}, {"family": "Witters", "given": "Hilda", "initials": "H", "orcid": "0000-0002-2026-3962", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c2165bc4a26b4fcc88e58740a6cab37a.json"}}, {"family": "Zdrazil", "given": "Barbara", "initials": "B", "orcid": "0000-0001-9395-1515", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3ac81e512aaf49b984436e937493c700.json"}}, {"family": "\u017dupani\u010d", "given": "An\u017ee", "initials": "A", "orcid": "0000-0003-3303-9086", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/e04ae2897f2741138dcad3babd50c451.json"}}, {"family": "Willighagen", "given": "Egon L", "initials": "EL", "orcid": "0000-0001-7542-0286", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f6af0a094c4a4ac1ab7fa07c7363ee21.json"}}], "type": "journal article", "published": "2023-10-03", "journal": {"title": "F1000Res", "issn": "2046-1402", "volume": "10", "issn-l": "2046-1402"}, "abstract": "Toxicology has been an active research field for many decades, with academic, industrial and government involvement. Modern omics and computational approaches are changing the field, from merely disease-specific observational models into target-specific predictive models. Traditionally, toxicology has strong links with other fields such as biology, chemistry, pharmacology and medicine. With the rise of synthetic and new engineered materials, alongside ongoing prioritisation needs in chemical risk assessment for existing chemicals, early predictive evaluations are becoming of utmost importance to both scientific and regulatory purposes. ELIXIR is an intergovernmental organisation that brings together life science resources from across Europe. To coordinate the linkage of various life science efforts around modern predictive toxicology, the establishment of a new ELIXIR Community is seen as instrumental. In the past few years, joint efforts, building on incidental overlap, have been piloted in the context of ELIXIR. For example, the EU-ToxRisk, diXa, HeCaToS, transQST, and the nanotoxicology community have worked with the ELIXIR TeSS, Bioschemas, and Compute Platforms and activities. In 2018, a core group of interested parties wrote a proposal, outlining a sketch of what this new ELIXIR Toxicology Community would look like. A recent workshop (held September 30th to October 1st, 2020) extended this into an ELIXIR Toxicology roadmap and a shortlist of limited investment-high gain collaborations to give body to this new community. This Whitepaper outlines the results of these efforts and defines our vision of the ELIXIR Toxicology Community and how it complements other ELIXIR activities.", "doi": "10.12688/f1000research.74502.2", "pmid": "37842337", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC10568213"}, {"db": "pii", "key": "ELIXIR-1129"}], "notes": [], "created": "2026-08-20T12:41:46.796Z", "modified": "2026-08-20T12:41:46.982Z"}, {"entity": "publication", "iuid": "b6a320409e2149cdbfdc1dfdc315fa17", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/b6a320409e2149cdbfdc1dfdc315fa17.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/b6a320409e2149cdbfdc1dfdc315fa17"}}, "title": "ELIXIR and Toxicology: a community in development", "authors": [{"family": "Martens", "given": "Marvin", "initials": "M", "orcid": "0000-0003-2230-0840", "researcher": {"href": 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"https://publications-affiliated.scilifelab.se/researcher/11c7f6e4f5a646fab5020f2afcaed4ca.json"}}, {"family": "Witters", "given": "Hilda", "initials": "H", "orcid": "0000-0002-2026-3962", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c2165bc4a26b4fcc88e58740a6cab37a.json"}}, {"family": "Zdrazil", "given": "Barbara", "initials": "B", "orcid": "0000-0001-9395-1515", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3ac81e512aaf49b984436e937493c700.json"}}, {"family": "\u017dupani\u010d", "given": "An\u017ee", "initials": "A", "orcid": "0000-0003-3303-9086", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/e04ae2897f2741138dcad3babd50c451.json"}}, {"family": "Willighagen", "given": "Egon L", "initials": "EL", "orcid": "0000-0001-7542-0286", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f6af0a094c4a4ac1ab7fa07c7363ee21.json"}}], "type": "journal-article", "published": "2021-11-08", "journal": {"title": "F1000Res", "issn": "2046-1402", "volume": "10", "pages": "1129", "issn-l": "2046-1402"}, "abstract": null, "doi": "10.12688/f1000research.74502.1", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T12:41:44.020Z", "modified": "2026-08-20T12:41:44.651Z"}, {"entity": "publication", "iuid": "f1336fd3bdbe4d0fab56982fc188721c", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/f1336fd3bdbe4d0fab56982fc188721c.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/f1336fd3bdbe4d0fab56982fc188721c"}}, "title": "Defining the Scope of Exposome Studies and Research Needs from a Multidisciplinary Perspective.", "authors": [{"family": "Zhang", "given": "Pei", "initials": "P", "orcid": "0000-0003-2054-928X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/2e4af492258b4256992af0279c823400.json"}}, {"family": "Carlsten", "given": "Christopher", "initials": "C"}, {"family": "Chaleckis", "given": "Romanas", "initials": "R", "orcid": "0000-0001-8042-1005", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/012934b6c4a64891b76722fbda1e0f28.json"}}, {"family": "Hanhineva", "given": "Kati", "initials": "K", "orcid": "0000-0001-6834-7375", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b66883342d1b45938f17d75e73479d50.json"}}, {"family": "Huang", "given": "Mengna", "initials": "M", "orcid": "0000-0002-4626-4816", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/baf43d2b06f746078bd69385c9e6cf93.json"}}, {"family": "Isobe", "given": "Tomohiko", "initials": "T", "orcid": "0000-0001-9235-1227", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/67986b3e12c1468c9b7cea2709e233a1.json"}}, {"family": "Koistinen", "given": "Ville M", "initials": "VM"}, {"family": "Meister", "given": "Isabel", "initials": "I"}, {"family": "Papazian", "given": "Stefano", "initials": "S"}, {"family": "Sdougkou", "given": "Kalliroi", "initials": "K"}, {"family": "Xie", "given": "Hongyu", "initials": "H"}, {"family": "Martin", "given": "Jonathan W", "initials": "JW", "orcid": "0000-0001-6265-4294", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/02199c0d99674e2ea5e96e6589c07a00.json"}}, {"family": "Rappaport", "given": "Stephen M", "initials": "SM", "orcid": "0000-0002-3806-0848", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/da3132c271b34cc8a758560a68fe241b.json"}}, {"family": "Tsugawa", "given": "Hiroshi", "initials": "H", "orcid": "0000-0002-2015-3958", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1703a87b2e3444d8ba917253d25d5556.json"}}, {"family": "Walker", "given": "Douglas I", "initials": "DI", "orcid": "0000-0003-2912-398X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4712c06efd674e4b96f494e33ab9084f.json"}}, {"family": "Woodruff", "given": "Tracey J", "initials": "TJ", "orcid": "0000-0003-3622-1297", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3ad211bff7564b65ad1a4d6468e0e6b7.json"}}, {"family": "Wright", "given": "Robert O", "initials": "RO"}, {"family": "Wheelock", "given": "Craig E", "initials": "CE", "orcid": "0000-0002-8113-0653", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5d98abddc2b14a35ade5cb6d6d2f540d.json"}}], "type": "journal article", "published": "2021-10-12", "journal": {"title": "Environ Sci Technol Lett", "issn": "2328-8930", "volume": "8", "issue": "10", "pages": "839-852", "issn-l": null}, "abstract": "The concept of the exposome was introduced over 15 years ago to reflect the important role that the environment exerts on health and disease. While originally viewed as a call-to-arms to develop more comprehensive exposure assessment methods applicable at the individual level and throughout the life course, the scope of the exposome has now expanded to include the associated biological response. In order to explore these concepts, a workshop was hosted by the Gunma University Initiative for Advanced Research (GIAR, Japan) to discuss the scope of exposomics from an international and multidisciplinary perspective. This Global Perspective is a summary of the discussions with emphasis on (1) top-down, bottom-up, and functional approaches to exposomics, (2) the need for integration and standardization of LC- and GC-based high-resolution mass spectrometry methods for untargeted exposome analyses, (3) the design of an exposomics study, (4) the requirement for open science workflows including mass spectral libraries and public databases, (5) the necessity for large investments in mass spectrometry infrastructure in order to sequence the exposome, and (6) the role of the exposome in precision medicine and nutrition to create personalized environmental exposure profiles. Recommendations are made on key issues to encourage continued advancement and cooperation in exposomics.", "doi": "10.1021/acs.estlett.1c00648", "pmid": "34660833", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC8515788"}], "notes": [], "created": "2026-08-20T08:10:04.602Z", "modified": "2026-08-20T08:10:05.065Z"}]}