{"entity": "researcher", "timestamp": "2026-09-30T15:06:20.732Z", "family": "Accardi", "given": "Giulia", "initials": "G", "orcid": "0000-0003-3565-9529", "affiliations": ["Laboratory of Immunopathology and Immunosenescence, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Palermo, Italy."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/5c4a1133c0d64cb086c82df6f2f71b6a.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/5c4a1133c0d64cb086c82df6f2f71b6a"}}, "publications": [{"entity": "publication", "iuid": "19cc4919ae204388904fdae4fb3c21d8", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/19cc4919ae204388904fdae4fb3c21d8.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/19cc4919ae204388904fdae4fb3c21d8"}}, "title": "Plasma proteome profiling of healthy individuals across the life span in a Sicilian cohort with long-lived individuals.", "authors": [{"family": "Siino", "given": "Valentina", "initials": "V", "orcid": "0000-0002-0489-6380", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b03ef29e68614191b1cd56f3f8606be9.json"}}, {"family": "Ali", "given": "Ashfaq", "initials": "A", "orcid": "0000-0002-0164-2166", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ee7617286a8c47f9b1ac9343a417ab71.json"}}, {"family": "Accardi", "given": "Giulia", "initials": "G", "orcid": "0000-0003-3565-9529", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5c4a1133c0d64cb086c82df6f2f71b6a.json"}}, {"family": "Aiello", "given": "Anna", "initials": "A", "orcid": "0000-0003-2593-3221", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/df0abb04e1654814929411a55c845387.json"}}, {"family": "Ligotti", "given": "Mattia E", "initials": "ME"}, {"family": "Mosquim Junior", "given": "Sergio", "initials": "S"}, {"family": "Candore", "given": "Giuseppina", "initials": "G", "orcid": "0000-0002-9966-934X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7319de1ea5914c59a30a493cde505b07.json"}}, {"family": "Caruso", "given": "Calogero", "initials": "C", "orcid": "0000-0001-8004-2363", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/a6ba0026e36643679376f7552240c3da.json"}}, {"family": "Levander", "given": "Fredrik", "initials": "F", "orcid": "0000-0002-0710-9792", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d3aaa3dcdb4f4e9f9b4bd44097d85d0c.json"}}, {"family": "Vasto", "given": "Sonya", "initials": "S", "orcid": "0000-0002-6033-4745", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/624a61c7e0cd43c4ade30bf7ca0e7dda.json"}}], "type": "journal article", "published": "2022-09-00", "journal": {"title": "Aging Cell", "issn": "1474-9726", "volume": "21", "issue": "9", "pages": "e13684", "issn-l": "1474-9718"}, "abstract": "The study of healthy human aging is important for shedding light on the molecular mechanisms behind aging to promote well-being and to possibly predict and/or avoid the development of age-related disorders such as atherosclerosis and diabetes. Herein, we have employed an untargeted mass spectrometry-based approach to study age-related protein changes in a healthy Sicilian plasma cohort including long-lived individuals. This approach confirmed some of the previously known proteins correlated with age including fibulin-1, dystroglycan, and gamma-glutamyl hydrolase. Furthermore, our findings include novel proteins that correlate with age and/or with location and uric acid, which could represent a unique signature for healthy aging.", "doi": "10.1111/acel.13684", "pmid": "35932462", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC9470904"}], "notes": [], "created": "2026-09-23T10:08:03.919Z", "modified": "2026-09-23T10:46:09.830Z"}]}