{"entity": "researcher", "timestamp": "2026-09-29T15:20:43.507Z", "family": "Hauser", "given": "Janosch", "initials": "J", "orcid": "0000-0003-3601-0342", "affiliations": ["KTH Royal Institute of Technology, Micro and Nanosystems, 10044 Stockholm, Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/5af3bab867554f0fbfdfb035acbadac0.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/5af3bab867554f0fbfdfb035acbadac0"}}, "publications": [{"entity": "publication", "iuid": "f9ebf0790c9041a8b06026f3128b1c99", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/f9ebf0790c9041a8b06026f3128b1c99.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/f9ebf0790c9041a8b06026f3128b1c99"}}, "title": "Microfluidic Device for Patient-Centric Multiplexed Assays with Readout in Centralized Laboratories.", "authors": [{"family": "Hauser", "given": "Janosch", "initials": "J", "orcid": "0000-0003-3601-0342", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5af3bab867554f0fbfdfb035acbadac0.json"}}, {"family": "Dale", "given": "Matilda", "initials": "M"}, {"family": "Beck", "given": "Olof", "initials": "O"}, {"family": "Schwenk", "given": "Jochen M", "initials": "JM", "orcid": "0000-0001-8141-8449", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/022e140799b6466ea123319c3d70c76e.json"}}, {"family": "Stemme", "given": "G\u00f6ran", "initials": "G", "orcid": "0000-0001-9552-4234", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/122f084eea624e5a801c8fafa6d48f6a.json"}}, {"family": "Fredolini", "given": "Claudia", "initials": "C"}, {"family": "Roxhed", "given": "Niclas", "initials": "N", "orcid": "0000-0002-7147-6730", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/479a5ae1d69b42859bce8537851586ce.json"}}], "type": "journal article", "published": "2023-01-17", "journal": {"title": "Anal. Chem.", "issn": "1520-6882", "volume": "95", "issue": "2", "pages": "1350-1358", "issn-l": "0003-2700"}, "abstract": "Patient-centric sampling strategies, where the patient performs self-sampling and ships the sample to a centralized laboratory for readout, are on the verge of widespread adaptation. However, the key to a successful patient-centric workflow is user-friendliness, with few noncritical user interactions, and simple, ideally biohazard-free shipment. Here, we present a capillary-driven microfluidic device designed to perform the critical biomarker capturing step of a multiplexed immunoassay at the time of sample collection. On-chip sample drying enables biohazard-free shipment and allows us to make use of advanced analytics of specialized laboratories that offer the needed analytical sensitivity, reliability, and affordability. Using C-Reactive Protein, MCP1, S100B, IGFBP1, and IL6 as model blood biomarkers, we demonstrate the multiplexing capability and applicability of the device to a patient-centric workflow. The presented quantification of a biomarker panel opens up new possibilities for e-doctor and e-health applications.", "doi": "10.1021/acs.analchem.2c04318", "pmid": "36548393", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC9850402"}], "notes": [], "created": "2026-09-23T12:20:28.073Z", "modified": "2026-09-23T12:20:28.181Z"}]}