{"entity": "researcher", "timestamp": "2026-05-17T08:39:42.343Z", "family": "Berendonk", "given": "Thomas U", "initials": "TU", "orcid": "0000-0002-9301-1803", "affiliations": [], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/4c66286f83a8430f954fbc5c52db10c5.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/4c66286f83a8430f954fbc5c52db10c5"}}, "publications": [{"entity": "publication", "iuid": "fd78ef4d1eb142daa15397e72f19853d", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/fd78ef4d1eb142daa15397e72f19853d.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/fd78ef4d1eb142daa15397e72f19853d"}}, "title": "Fish are poor sentinels for surveillance of riverine antimicrobial resistance.", "authors": [{"family": "Tskhay", "given": "Faina", "initials": "F", "orcid": "0000-0001-8700-3279", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/66867423459544e7a72b0a9090a46cee.json"}}, {"family": "K\u00f6bsch", "given": "Christoph", "initials": "C", "orcid": "0000-0002-9748-2039", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ebe319eddda54827bf9ac3970e91a733.json"}}, {"family": "Elena", "given": "Alan X", "initials": "AX", "orcid": "0000-0001-5372-0923", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/005e2b93413c4627a222eb7a5ef66e04.json"}}, {"family": "Bengtsson-Palme", "given": "Johan", "initials": "J", "orcid": "0000-0002-6528-3158", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4c666068e9d34939b0252a627007cec7.json"}}, {"family": "Berendonk", "given": "Thomas U", "initials": "TU", "orcid": "0000-0002-9301-1803", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4c66286f83a8430f954fbc5c52db10c5.json"}}, {"family": "Kl\u00fcmper", "given": "Uli", "initials": "U", "orcid": "0000-0002-4169-6548", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7d8605cdbfc14403b607a3b5ace7249d.json"}}], "type": "journal article", "published": "2025-06-00", "journal": {"title": "One Health", "issn": "2352-7714", "volume": "20", "pages": "101026", "issn-l": null}, "abstract": "Effective surveillance of antimicrobial resistance (AMR) in the environment is crucial for assessing the human and animal health risk of AMR pollution. Wastewater treatment plants (WWTPs) are one of the main sources of AMR pollutants discharged into water bodies. One important factor for assessing the risks associated with such pollution is the colonization potential of the resistant bacteria (ARB) and resistance genes (ARGs) from the environment into human or animal microbiomes upon exposure. This study explores whether fish can act as sentinels for surveillance of AMR pollution in general and specifically the human colonization potential of ARB in rivers impacted by WWTP effluents. Two riverine fish species, Brown trout, and European bullhead, were sampled up- and downstream a German WWTP. The two fish species were chosen due to their different lifestyles: Trout are mainly actively swimming in the water phase, while bullheads are sedentary and river sediment-associated. The bacterial microbiomes and resistomes of fish gills, skin, and feces were compared with those of the respective river water and sediment up- and downstream of the WWTP. Microbiomes of both fish mirrored the changes in river water and sediment downstream of the WWTP, with significant shifts in bacterial community composition, particularly an increase in Proteobacteria and Verrucomicrobia. However, increases in ARG abundances observed in water and sediment downstream of the WWTP were not reflected in any of the fish-associated resistomes. This indicates that while the fish microbiome is sensitive to environmental changes, resistomes of poikilothermic animals such as fish are less responsive to colonization by ARB originating from WWTPs and may not serve as effective sentinels for assessing AMR pollution and colonization risks in freshwater environments. This study highlights the complexity of using wildlife as indicators for environmental AMR pollution and suggests that other species are better suited for surveillance efforts.", "doi": "10.1016/j.onehlt.2025.101026", "pmid": "40236740", "labels": {"Johan Bengtsson-Palme": null, "DDLS Fellow": null}, "xrefs": [{"db": "pmc", "key": "PMC11999348"}, {"db": "pii", "key": "S2352-7714(25)00062-X"}], "notes": [], "created": "2025-06-04T08:12:42.896Z", "modified": "2025-09-09T09:29:29.395Z"}, {"entity": "publication", "iuid": "7d80eacd707b42e79fdec1d031200057", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/7d80eacd707b42e79fdec1d031200057.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/7d80eacd707b42e79fdec1d031200057"}}, "title": "Environmental reservoir of resistance genes for the last resort antibiotic Cefiderocol", "authors": [{"family": "Gschwind", "given": "Remi", "initials": "R", "orcid": "0000-0001-7741-9764", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/287bf0d97cad4eb7b389fa0a8495e86b.json"}}, {"family": "Bonnet", "given": "Mehdi", "initials": "M"}, {"family": "Abramova", "given": "Anna", "initials": "A", "orcid": "0000-0002-0493-7808", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/dd75cbcc659c4ca398eb678fad1dc498.json"}}, {"family": "Jarqu\u00edn-D\u00edaz", "given": "Victor Hugo", "initials": "VH", "orcid": "0000-0003-3758-1091", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d573d1cb515a4c75b3c8ff2f97be419a.json"}}, {"family": "Wenne", "given": "Marcus", "initials": "M", "orcid": "0009-0008-1941-4146", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/90d60a98a3b54120b369ffe5dd29c854.json"}}, {"family": "L\u00f6ber", "given": "Ulrike", "initials": "U", "orcid": "0000-0001-7468-9531", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b71c22b8d28b46e490fa499603ada68d.json"}}, {"family": "Godron", "given": "Nicolas", "initials": "N", "orcid": "0009-0004-4143-5462", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0285cb4da845488b97f091bc0d3acac5.json"}}, {"family": "Kampouris", "given": "Ioannis D", "initials": "ID", "orcid": "0000-0003-2093-5930", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/2a58d348ca1f496d8c3915e23c411a6c.json"}}, {"family": "Tskhay", "given": "Faina", "initials": "F", "orcid": "0000-0001-8700-3279", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/66867423459544e7a72b0a9090a46cee.json"}}, {"family": "Naheed", "given": "Fouzia", "initials": "F"}, {"family": "Debroucker", "given": "Chlo\u00e9", "initials": "C"}, {"family": "Bui-Hai", "given": "Maximilien", "initials": "M"}, {"family": "Aiba", "given": "In\u00e8s El", "initials": "IE"}, {"family": "Kl\u00fcmper", "given": "Uli", "initials": "U", "orcid": "0000-0002-4169-6548", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7d8605cdbfc14403b607a3b5ace7249d.json"}}, {"family": "Berendonk", "given": "Thomas U", "initials": "TU", "orcid": "0000-0002-9301-1803", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4c66286f83a8430f954fbc5c52db10c5.json"}}, {"family": "Forslund-Startceva", "given": "Sofia K", "initials": "SK", "orcid": "0000-0003-4285-6993", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/80bd453b4d084425948404417485140b.json"}}, {"family": "Zahra", "given": "Rabaab", "initials": "R", "orcid": "0000-0001-8784-0114", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/a678f0c2414244ac894b5f0540b5ef5f.json"}}, {"family": "Bengtsson-Palme", "given": "Johan", "initials": "J", "orcid": "0000-0002-6528-3158", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4c666068e9d34939b0252a627007cec7.json"}}, {"family": "Ruppe", "given": "Etienne", "initials": "E"}], "type": "posted-content", "published": "2025-05-26", "journal": {"issn-l": null}, "abstract": null, "doi": "10.1101/2025.05.26.656069", "pmid": null, "labels": {"Johan Bengtsson-Palme": null, "DDLS Fellow": null}, "xrefs": [], "notes": [], "created": "2025-06-04T08:15:56.666Z", "modified": "2025-09-09T09:29:47.219Z"}, {"entity": "publication", "iuid": "7d17c7de81cf4c79af7dcb60c8a3d885", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/7d17c7de81cf4c79af7dcb60c8a3d885.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/7d17c7de81cf4c79af7dcb60c8a3d885"}}, "title": "Fish are poor sentinels for surveillance of riverine AMR", "authors": [{"family": "Tskhay", "given": "Faina", "initials": "F", "orcid": "0000-0001-8700-3279", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/66867423459544e7a72b0a9090a46cee.json"}}, {"family": "K\u00f6bsch", "given": "Christoph", "initials": "C", "orcid": "0000-0002-9748-2039", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ebe319eddda54827bf9ac3970e91a733.json"}}, {"family": "Elena", "given": "Alan X", "initials": "AX", "orcid": "0000-0001-5372-0923", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/005e2b93413c4627a222eb7a5ef66e04.json"}}, {"family": "Bengtsson-Palme", "given": "Johan", "initials": "J", "orcid": "0000-0002-6528-3158", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4c666068e9d34939b0252a627007cec7.json"}}, {"family": "Berendonk", "given": "Thomas U", "initials": "TU", "orcid": "0000-0002-9301-1803", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4c66286f83a8430f954fbc5c52db10c5.json"}}, {"family": "Kl\u00fcmper", "given": "Uli", "initials": "U", "orcid": "0000-0002-4169-6548", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7d8605cdbfc14403b607a3b5ace7249d.json"}}], "type": "posted-content", "published": "2024-10-22", "journal": {"issn-l": null}, "abstract": null, "doi": "10.1101/2024.10.22.619632", "pmid": null, "labels": {"DDLS Fellow": null, "Johan Bengtsson-Palme": null}, "xrefs": [], "notes": [], "created": "2024-11-18T11:45:27.075Z", "modified": "2025-12-04T16:53:36.360Z"}, {"entity": "publication", "iuid": "1dd5448da4264efab44a0f27d42fad69", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/1dd5448da4264efab44a0f27d42fad69.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/1dd5448da4264efab44a0f27d42fad69"}}, "title": "A global baseline for qPCR-determined antimicrobial resistance gene prevalence across environments.", "authors": [{"family": "Abramova", "given": "Anna", "initials": "A", "orcid": "0000-0002-0493-7808", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/dd75cbcc659c4ca398eb678fad1dc498.json"}}, {"family": "Berendonk", "given": "Thomas U", "initials": "TU", "orcid": "0000-0002-9301-1803", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4c66286f83a8430f954fbc5c52db10c5.json"}}, {"family": "Bengtsson-Palme", "given": "Johan", "initials": "J", "orcid": "0000-0002-6528-3158", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4c666068e9d34939b0252a627007cec7.json"}}], "type": "review", "published": "2023-08-00", "journal": {"title": "Environ Int", "issn": "1873-6750", "issn-l": "0160-4120", "volume": "178", "issue": null, "pages": "108084"}, "abstract": "The environment is an important component in the emergence and transmission of antimicrobial resistance (AMR). Despite that, little effort has been made to monitor AMR outside of clinical and veterinary settings. Partially, this is caused by a lack of comprehensive reference data for the vast majority of environments. To enable monitoring to detect deviations from the normal background resistance levels in the environment, it is necessary to establish a baseline of AMR in a variety of settings. In an attempt to establish this baseline level, we here performed a comprehensive literature survey, identifying 150 scientific papers containing relevant qPCR data on antimicrobial resistance genes (ARGs) in environments associated with potential routes for AMR dissemination. The collected data included 1594 samples distributed across 30 different countries and 12 sample types, in a time span from 2001 to 2020. We found that for most ARGs, the typically reported abundances in human impacted environments fell in an interval from 10-5 to 10-3 copies per 16S rRNA, roughly corresponding to one ARG copy in a thousand bacteria. Altogether these data represent a comprehensive overview of the occurrence and levels of ARGs in different environments, providing background data for risk assessment models within current and future AMR monitoring frameworks.", "doi": "10.1016/j.envint.2023.108084", "pmid": "37421899", "labels": {"DDLS Fellow": null, "Johan Bengtsson-Palme": null}, "xrefs": [{"db": "pii", "key": "S0160-4120(23)00357-4"}], "notes": [], "created": "2022-11-08T09:31:13.181Z", "modified": "2024-11-18T11:42:53.864Z"}, {"entity": "publication", "iuid": "83596194452742659a225044f49b5c0d", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/83596194452742659a225044f49b5c0d.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/83596194452742659a225044f49b5c0d"}}, "title": "The global groundwater resistome: core antibiotic resistance genes, their dynamics and drivers", "authors": [{"family": "Kampouris", "given": "Ioannis D", "initials": "ID", "orcid": "0000-0003-2093-5930", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/2a58d348ca1f496d8c3915e23c411a6c.json"}}, {"family": "Bengtsson-Palme", "given": "Johan", "initials": "J", "orcid": "0000-0002-6528-3158", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4c666068e9d34939b0252a627007cec7.json"}}, {"family": "Babin", "given": "Doreen", "initials": "D", "orcid": "0000-0001-7144-8898", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/08f37fc331864001bf591275055c77a0.json"}}, {"family": "Gallego", "given": "Sara", "initials": "S", "orcid": "0000-0002-4521-5879", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ed3f2793013a43df9a4343a086bf9344.json"}}, {"family": "Li", "given": "Bing", "initials": "B"}, {"family": "Smalla", "given": "Kornelia", "initials": "K", "orcid": "0000-0001-6980-729X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8b633d4578e0468aa449a427329d4182.json"}}, {"family": "Berendonk", "given": "Thomas U", "initials": "TU", "orcid": "0000-0002-9301-1803", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4c66286f83a8430f954fbc5c52db10c5.json"}}, {"family": "Kl\u00fcmper", "given": "Uli", "initials": "U", "orcid": "0000-0002-4169-6548", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7d8605cdbfc14403b607a3b5ace7249d.json"}}], "type": "posted-content", "published": "2022-11-15", "journal": {"issn-l": null}, "abstract": null, "doi": "10.1101/2022.11.14.516424", "pmid": null, "labels": {"DDLS Fellow": null, "Johan Bengtsson-Palme": null}, "xrefs": [], "notes": [], "created": "2024-11-18T11:45:41.639Z", "modified": "2024-11-18T11:45:41.872Z"}]}