{"entity": "researcher", "timestamp": "2026-09-30T23:40:00.421Z", "family": "Akpan", "given": "Ekemini D", "initials": "ED", "orcid": "0000-0003-2402-3402", "affiliations": ["Catalysis and Peptide Research Unit, University of KwaZulu Natal Durban South Africa 4001 Naickert1@ukzn.ac.za."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/33ce1b064f334a098944ec62d2b22acb.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/33ce1b064f334a098944ec62d2b22acb"}}, "publications": [{"entity": "publication", "iuid": "2ac18d5af4454b5993a63e6d371e22c6", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/2ac18d5af4454b5993a63e6d371e22c6.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/2ac18d5af4454b5993a63e6d371e22c6"}}, "title": "Synthesis of novel 1,2,4-thiadiazinane 1,1-dioxides via three component SuFEx type reaction.", "authors": [{"family": "Khumalo", "given": "Mzilikazi F", "initials": "MF"}, {"family": "Akpan", "given": "Ekemini D", "initials": "ED", "orcid": "0000-0003-2402-3402", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/33ce1b064f334a098944ec62d2b22acb.json"}}, {"family": "Chinthakindi", "given": "Praveen K", "initials": "PK", "orcid": "0000-0002-8344-2415", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/99e8d26b04bd47a8a612239c49b8bf78.json"}}, {"family": "Brasil", "given": "Edikarlos M", "initials": "EM", "orcid": "0000-0002-8837-2428", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9831c11b91bc4cf6bf2951a05081737d.json"}}, {"family": "Rajbongshi", "given": "Kamal K", "initials": "KK", "orcid": "0000-0003-0128-663X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/a1473c288f83416a823fb0b599f003b3.json"}}, {"family": "Makatini", "given": "Maya M", "initials": "MM"}, {"family": "Govender", "given": "Thavendran", "initials": "T", "orcid": "0000-0003-2511-2503", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/77ef43839d9e476f95d124c9c34b81fa.json"}}, {"family": "Kruger", "given": "Hendrik G", "initials": "HG", "orcid": "0000-0003-0606-2053", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/88f669867879452ca86ab92c27fd285c.json"}}, {"family": "Naicker", "given": "Tricia", "initials": "T", "orcid": "0000-0002-7134-6258", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f5b1b1625e8c43859647736baa3e83d9.json"}}, {"family": "Arvidsson", "given": "Per I", "initials": "PI", "orcid": "0000-0002-9453-6812", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/84789ce64d004c83919336cdf43c903e.json"}}], "type": "journal article", "published": "2018-11-01", "journal": {"title": "RSC Adv.", "issn": "2046-2069", "volume": "8", "issue": "65", "pages": "37503-37507", "issn-l": "2046-2069"}, "abstract": "Herein, we report the preparation of 1,2,4-thiadiazinane 1,1-dioxides from reaction of \u03b2-aminoethane sulfonamides with dichloromethane, dibromomethane and formaldehyde as methylene donors. The \u03b2-aminoethane sulfonamides were obtained through sequential Michael addition of amines to \u03b1,\u03b2-unsaturated ethenesulfonyl fluorides followed by further DBU mediated sulfur(vi) fluoride exchange (SuFEx) reaction with amines at the S-F bond.", "doi": "10.1039/c8ra07627h", "pmid": "35557800", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC9089429"}, {"db": "pii", "key": "c8ra07627h"}], "notes": [], "created": "2026-09-23T12:40:39.586Z", "modified": "2026-09-23T12:40:39.905Z"}]}