{"entity": "researcher", "timestamp": "2026-08-20T21:26:58.072Z", "family": "Kloos", "given": "Marco", "initials": "M", "orcid": "0000-0002-8745-9740", "affiliations": ["European XFEL, Holzkoppel 4, 22869 Schenefeld, Germany."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/30f60d7edeaa451b9c6862c3d797814c.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/30f60d7edeaa451b9c6862c3d797814c"}}, "publications": [{"entity": "publication", "iuid": "3b6918deed394fb1a8a2d3d7877e3f9e", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/3b6918deed394fb1a8a2d3d7877e3f9e.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/3b6918deed394fb1a8a2d3d7877e3f9e"}}, "title": "3D-printed sheet jet for stable megahertz liquid sample delivery at X-ray free-electron lasers.", "authors": [{"family": "Konold", "given": "Patrick E", "initials": "PE"}, {"family": "You", "given": "Tong", "initials": "T"}, {"family": "Bielecki", "given": "Johan", "initials": "J"}, {"family": "Valerio", "given": "Joana", "initials": "J", "orcid": "0000-0001-5931-0925", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/38ebd6b25c87437095a47c1b7bf44ecd.json"}}, {"family": "Kloos", "given": "Marco", "initials": "M", "orcid": "0000-0002-8745-9740", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/30f60d7edeaa451b9c6862c3d797814c.json"}}, {"family": "Westphal", "given": "Daniel", "initials": "D", "orcid": "0000-0001-8735-0369", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8b65c15572f045bebbd2b3e54d3361ca.json"}}, {"family": "Bellisario", "given": "Alfredo", "initials": "A", "orcid": "0000-0001-5155-4431", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/026e73cf9b2f4f928c0bf8f91d974ec7.json"}}, {"family": "Varma Yenupuri", "given": "Tej", "initials": "T"}, {"family": "Wollter", "given": "August", "initials": "A"}, {"family": "Koliyadu", "given": "Jayanath C P", "initials": "JCP", "orcid": "0000-0002-0245-3842", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/dbd250665f634af0a3643eb5ec8d1f87.json"}}, {"family": "Koua", "given": "Faisal H M", "initials": "FHM", "orcid": "0000-0001-8371-9587", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/645de87b1d924a7b9bd5e25aefabbb21.json"}}, {"family": "Letrun", "given": "Romain", "initials": "R", "orcid": "0000-0002-0569-5193", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d8f34ffb59024c8483d554b06be94457.json"}}, {"family": "Round", "given": "Adam", "initials": "A", "orcid": "0000-0002-0723-8228", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0945f297d3d347388f689f02bf43fd2b.json"}}, {"family": "Sato", "given": "Tokushi", "initials": "T", "orcid": "0000-0003-3155-3487", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9a6ff4a0efb547fe8d1989561009e840.json"}}, {"family": "M\u00e9sz\u00e1ros", "given": "Petra", "initials": "P"}, {"family": "Monrroy", "given": "Leonardo", "initials": "L", "orcid": "0000-0001-8852-9424", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7a1a74297e27463bbbb993b02307fb08.json"}}, {"family": "Mutisya", "given": "Jennifer", "initials": "J"}, {"family": "B\u00f3dizs", "given": "Szabolcs", "initials": "S"}, {"family": "Larkiala", "given": "Taru", "initials": "T", "orcid": "0009-0004-4180-1311", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4210b0e1f3984d38a7efb5eb11e47177.json"}}, {"family": "Nimmrich", "given": "Amke", "initials": "A", "orcid": "0000-0003-0425-2101", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/136bad817bdf47a09bc2202cf5eb47e7.json"}}, {"family": "Alvarez", "given": "Roberto", "initials": "R"}, {"family": "Adams", "given": "Patrick", "initials": "P"}, {"family": "Bean", "given": "Richard", "initials": "R"}, {"family": "Ekeberg", "given": "Tomas", "initials": "T", "orcid": "0000-0003-0092-2104", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ba9bc0d5dda542ef9f69da623557a977.json"}}, {"family": "Kirian", "given": "Richard A", "initials": "RA", "orcid": "0000-0001-7197-3086", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8b7cc39ee4614a52a470e386ffd469af.json"}}, {"family": "Martin", "given": "Andrew V", "initials": "AV"}, {"family": "Westenhoff", "given": "Sebastian", "initials": "S"}, {"family": "Maia", "given": "Filipe R N C", "initials": "FRNC"}], "type": "journal article", "published": "2023-11-01", "journal": {"title": "IUCrJ", "issn": "2052-2525", "volume": "10", "issue": "Pt 6", "pages": "662-670", "issn-l": "2052-2525"}, "abstract": "X-ray free-electron lasers (XFELs) can probe chemical and biological reactions as they unfold with unprecedented spatial and temporal resolution. A principal challenge in this pursuit involves the delivery of samples to the X-ray interaction point in such a way that produces data of the highest possible quality and with maximal efficiency. This is hampered by intrinsic constraints posed by the light source and operation within a beamline environment. For liquid samples, the solution typically involves some form of high-speed liquid jet, capable of keeping up with the rate of X-ray pulses. However, conventional jets are not ideal because of radiation-induced explosions of the jet, as well as their cylindrical geometry combined with the X-ray pointing instability of many beamlines which causes the interaction volume to differ for every pulse. This complicates data analysis and contributes to measurement errors. An alternative geometry is a liquid sheet jet which, with its constant thickness over large areas, eliminates the problems related to X-ray pointing. Since liquid sheets can be made very thin, the radiation-induced explosion is reduced, boosting their stability. These are especially attractive for experiments which benefit from small interaction volumes such as fluctuation X-ray scattering and several types of spectroscopy. Although their use has increased for soft X-ray applications in recent years, there has not yet been wide-scale adoption at XFELs. Here, gas-accelerated liquid sheet jet sample injection is demonstrated at the European XFEL SPB/SFX nano focus beamline. Its performance relative to a conventional liquid jet is evaluated and superior performance across several key factors has been found. This includes a thickness profile ranging from hundreds of nanometres to 60 nm, a fourfold increase in background stability and favorable radiation-induced explosion dynamics at high repetition rates up to 1.13 MHz. Its minute thickness also suggests that ultrafast single-particle solution scattering is a possibility.", "doi": "10.1107/S2052252523007972", "pmid": "37721770", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC10619454"}, {"db": "pii", "key": "S2052252523007972"}], "notes": [], "created": "2026-08-20T11:16:10.351Z", "modified": "2026-08-20T11:16:10.636Z"}]}