{"entity": "researcher", "timestamp": "2026-08-20T20:57:55.042Z", "family": "Silveira", "given": "Angela", "initials": "A", "orcid": "0000-0003-2063-4935", "affiliations": ["Department of Medicine Solna, Karolinska Institute and Karolinska University Hospital, Stockholm, Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/2d8cbafcc7f04ac3adda984af7d85a16.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/2d8cbafcc7f04ac3adda984af7d85a16"}}, "publications": [{"entity": "publication", "iuid": "88d46598d38049e49334326bc3a3c0bc", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/88d46598d38049e49334326bc3a3c0bc.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/88d46598d38049e49334326bc3a3c0bc"}}, "title": "Author Correction: Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism.", "authors": [{"family": "Iglesias", "given": "Maria Jesus", "initials": "MJ"}, {"family": "Sanchez-Rivera", "given": "Laura", "initials": "L"}, {"family": "Ibrahim-Kosta", "given": "Manal", "initials": "M"}, {"family": "Naudin", "given": "Cl\u00e9ment", "initials": "C", "orcid": "0000-0002-6777-9587", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f89e25cd7fcc4617ab5299c72fd17e0c.json"}}, {"family": "Munsch", "given": "Ga\u00eblle", "initials": "G", "orcid": "0000-0003-1564-9825", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ed62bf6aa35643f283511d68d2aa4b01.json"}}, {"family": "Goumidi", "given": "Louisa", "initials": "L", "orcid": "0000-0003-4164-8471", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7d3df066e5e54e32bb99110289ab8a45.json"}}, {"family": "Farm", "given": "Maria", "initials": "M"}, {"family": "Smith", "given": "Philip M", "initials": "PM"}, {"family": "Thibord", "given": "Florian", "initials": "F"}, {"family": "Kral-Pointner", "given": "Julia Barbara", "initials": "JB"}, {"family": "Hong", "given": "Mun-Gwan", "initials": "MG", "orcid": "0000-0001-8603-8293", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d12504acae5c4f31b83f75c3d7786cd4.json"}}, {"family": "Suchon", "given": "Pierre", "initials": "P"}, {"family": "Germain", "given": "Marine", "initials": "M"}, {"family": "Schrottmaier", "given": "Waltraud", "initials": "W", "orcid": "0000-0003-0550-4120", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0ab65a615b9e477aa6206677e57025b0.json"}}, {"family": "Dusart", "given": "Philip", "initials": "P", "orcid": "0000-0003-2747-3214", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/26cf50c230954da190746c16b5ac2b7d.json"}}, {"family": "Boland", "given": "Anne", "initials": "A"}, {"family": "Kotol", "given": "David", "initials": "D", "orcid": "0000-0002-5388-3826", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c41f8f491c474e6bba2047b5d04b4af5.json"}}, {"family": "Edfors", "given": "Fredrik", "initials": "F", "orcid": "0000-0002-0017-7987", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9e213b04f8984c8eb00c68f5bc2f6a36.json"}}, {"family": "Koprulu", "given": "Mine", "initials": "M", "orcid": "0000-0001-6870-4539", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/e8fa2ddd2cfa4bbeb9c0b043513a6701.json"}}, {"family": "Pietzner", "given": "Maik", "initials": "M", "orcid": "0000-0003-3437-9963", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3304844cece945168cbec0b5e3d9a9cf.json"}}, {"family": "Langenberg", "given": "Claudia", "initials": "C", "orcid": "0000-0002-5017-7344", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f287f3248cc24c6cbfc100c249b87418.json"}}, {"family": "Damrauer", "given": "Scott M", "initials": "SM", "orcid": "0000-0001-8009-1632", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f35b78d4384d41f2bfae2639b23b1e82.json"}}, {"family": "Johnson", "given": "Andrew D", "initials": "AD", "orcid": "0000-0001-6369-5178", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8b268f8da3f247ba90dc37ea73d93c2f.json"}}, {"family": "Klarin", "given": "Derek M", "initials": "DM", "orcid": "0000-0002-4636-5780", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0b81fbf037ec4b4b8ac0013544539f00.json"}}, {"family": "Smith", "given": "Nicholas L", "initials": "NL"}, {"family": "Smadja", "given": "David M", "initials": "DM"}, {"family": "Holmstr\u00f6m", "given": "Margareta", "initials": "M"}, {"family": "Magnusson", "given": "Maria", "initials": "M"}, {"family": "Silveira", "given": "Angela", "initials": "A", "orcid": "0000-0003-2063-4935", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/2d8cbafcc7f04ac3adda984af7d85a16.json"}}, {"family": "Uhl\u00e9n", "given": "Mathias", "initials": "M", "orcid": "0000-0002-4858-8056", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9ea446aa574042a295d5f69437402f76.json"}}, {"family": "Renn\u00e9", "given": "Thomas", "initials": "T"}, {"family": "Martinez-Perez", "given": "Angel", "initials": "A", "orcid": "0000-0002-5934-1454", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0fa8f32fb99f46dcb16d3a64643dbbfa.json"}}, {"family": "Emmerich", "given": "Joseph", "initials": "J"}, {"family": "Deleuze", "given": "Jean-Francois", "initials": "JF", "orcid": "0000-0002-5358-4463", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/33bb50dc6b8045bd9dbbde4423f66129.json"}}, {"family": "Antovic", "given": "Jovan", "initials": "J"}, {"family": "Soria Fernandez", "given": "Jose Manuel", "initials": "JM"}, {"family": "Assinger", "given": "Alice", "initials": "A", "orcid": "0000-0002-5670-5910", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ccb6bb03693c4c799f4cbb53e6ff7049.json"}}, {"family": "Schwenk", "given": "Jochen M", "initials": "JM", "orcid": "0000-0001-8141-8449", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/022e140799b6466ea123319c3d70c76e.json"}}, {"family": "Souto Andres", "given": "Joan Carles", "initials": "JC", "orcid": "0000-0003-2092-5142", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/164af41db2204f2591c719a8b024d32a.json"}}, {"family": "Morange", "given": "Pierre-Emmanuel", "initials": "PE", "orcid": "0000-0002-9065-722X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/50bca11c313740c299901843e86e5d48.json"}}, {"family": "Butler", "given": "Lynn Marie", "initials": "LM", "orcid": "0000-0002-2352-8217", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ca98647aea15499485d755977bd0869a.json"}}, {"family": "Tr\u00e9gou\u00ebt", "given": "David-Alexandre", "initials": "DA", "orcid": "0000-0001-9084-7800", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/74ca463a0d804b1ab97dac4750563220.json"}}, {"family": "Odeberg", "given": "Jacob", "initials": "J", "orcid": "0000-0003-0996-1644", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d6abb3fc822a4cacbf1d45224f2442f5.json"}}], "type": "published erratum", "published": "2023-11-27", "journal": {"title": "Nat Commun", "issn": "2041-1723", "volume": "14", "issue": "1", "pages": "7752", "issn-l": "2041-1723"}, "abstract": null, "doi": "10.1038/s41467-023-43764-4", "pmid": "38012230", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC10682365"}, {"db": "pii", "key": "10.1038/s41467-023-43764-4"}], "notes": [], "created": "2026-08-20T08:53:02.011Z", "modified": "2026-08-20T08:53:02.187Z"}, {"entity": "publication", "iuid": "3eab6f40adba4a1eaa807ee583bf2a28", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/3eab6f40adba4a1eaa807ee583bf2a28.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/3eab6f40adba4a1eaa807ee583bf2a28"}}, "title": "Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism.", "authors": [{"family": "Iglesias", "given": "Maria Jesus", "initials": "MJ"}, {"family": "Sanchez-Rivera", "given": "Laura", "initials": "L"}, {"family": "Ibrahim-Kosta", "given": "Manal", "initials": "M"}, {"family": "Naudin", "given": "Cl\u00e9ment", "initials": "C", "orcid": "0000-0002-6777-9587", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f89e25cd7fcc4617ab5299c72fd17e0c.json"}}, {"family": "Munsch", "given": "Ga\u00eblle", "initials": "G", "orcid": "0000-0003-1564-9825", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ed62bf6aa35643f283511d68d2aa4b01.json"}}, {"family": "Goumidi", "given": "Louisa", "initials": "L", "orcid": "0000-0003-4164-8471", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7d3df066e5e54e32bb99110289ab8a45.json"}}, {"family": "Farm", "given": "Maria", "initials": "M"}, {"family": "Smith", "given": "Philip M", "initials": "PM"}, {"family": "Thibord", "given": "Florian", "initials": "F"}, {"family": "Kral-Pointner", "given": "Julia Barbara", "initials": "JB"}, {"family": "Hong", "given": "Mun-Gwan", "initials": "MG", "orcid": "0000-0001-8603-8293", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d12504acae5c4f31b83f75c3d7786cd4.json"}}, {"family": "Suchon", "given": "Pierre", "initials": "P"}, {"family": "Germain", "given": "Marine", "initials": "M"}, {"family": "Schrottmaier", "given": "Waltraud", "initials": "W", "orcid": "0000-0003-0550-4120", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0ab65a615b9e477aa6206677e57025b0.json"}}, {"family": "Dusart", "given": "Philip", "initials": "P", "orcid": "0000-0003-2747-3214", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/26cf50c230954da190746c16b5ac2b7d.json"}}, {"family": "Boland", "given": "Anne", "initials": "A"}, {"family": "Kotol", "given": "David", "initials": "D", "orcid": "0000-0002-5388-3826", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c41f8f491c474e6bba2047b5d04b4af5.json"}}, {"family": "Edfors", "given": "Fredrik", "initials": "F", "orcid": "0000-0002-0017-7987", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9e213b04f8984c8eb00c68f5bc2f6a36.json"}}, {"family": "Koprulu", "given": "Mine", "initials": "M", "orcid": "0000-0001-6870-4539", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/e8fa2ddd2cfa4bbeb9c0b043513a6701.json"}}, {"family": "Pietzner", "given": "Maik", "initials": "M", "orcid": "0000-0003-3437-9963", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3304844cece945168cbec0b5e3d9a9cf.json"}}, {"family": "Langenberg", "given": "Claudia", "initials": "C", "orcid": "0000-0002-5017-7344", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f287f3248cc24c6cbfc100c249b87418.json"}}, {"family": "Damrauer", "given": "Scott M", "initials": "SM", "orcid": "0000-0001-8009-1632", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f35b78d4384d41f2bfae2639b23b1e82.json"}}, {"family": "Johnson", "given": "Andrew D", "initials": "AD", "orcid": "0000-0001-6369-5178", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8b268f8da3f247ba90dc37ea73d93c2f.json"}}, {"family": "Klarin", "given": "Derek M", "initials": "DM", "orcid": "0000-0002-4636-5780", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0b81fbf037ec4b4b8ac0013544539f00.json"}}, {"family": "Smith", "given": "Nicholas L", "initials": "NL"}, {"family": "Smadja", "given": "David M", "initials": "DM"}, {"family": "Holmstr\u00f6m", "given": "Margareta", "initials": "M"}, {"family": "Magnusson", "given": "Maria", "initials": "M"}, {"family": "Silveira", "given": "Angela", "initials": "A", "orcid": "0000-0003-2063-4935", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/2d8cbafcc7f04ac3adda984af7d85a16.json"}}, {"family": "Uhl\u00e9n", "given": "Mathias", "initials": "M", "orcid": "0000-0002-4858-8056", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9ea446aa574042a295d5f69437402f76.json"}}, {"family": "Renn\u00e9", "given": "Thomas", "initials": "T"}, {"family": "Martinez-Perez", "given": "Angel", "initials": "A", "orcid": "0000-0002-5934-1454", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0fa8f32fb99f46dcb16d3a64643dbbfa.json"}}, {"family": "Emmerich", "given": "Joseph", "initials": "J"}, {"family": "Deleuze", "given": "Jean-Francois", "initials": "JF", "orcid": "0000-0002-5358-4463", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/33bb50dc6b8045bd9dbbde4423f66129.json"}}, {"family": "Antovic", "given": "Jovan", "initials": "J"}, {"family": "Soria Fernandez", "given": "Jose Manuel", "initials": "JM"}, {"family": "Assinger", "given": "Alice", "initials": "A", "orcid": "0000-0002-5670-5910", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ccb6bb03693c4c799f4cbb53e6ff7049.json"}}, {"family": "Schwenk", "given": "Jochen M", "initials": "JM", "orcid": "0000-0001-8141-8449", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/022e140799b6466ea123319c3d70c76e.json"}}, {"family": "Souto Andres", "given": "Joan Carles", "initials": "JC", "orcid": "0000-0003-2092-5142", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/164af41db2204f2591c719a8b024d32a.json"}}, {"family": "Morange", "given": "Pierre-Emmanuel", "initials": "PE", "orcid": "0000-0002-9065-722X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/50bca11c313740c299901843e86e5d48.json"}}, {"family": "Butler", "given": "Lynn Marie", "initials": "LM", "orcid": "0000-0002-2352-8217", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ca98647aea15499485d755977bd0869a.json"}}, {"family": "Tr\u00e9gou\u00ebt", "given": "David-Alexandre", "initials": "DA", "orcid": "0000-0001-9084-7800", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/74ca463a0d804b1ab97dac4750563220.json"}}, {"family": "Odeberg", "given": "Jacob", "initials": "J", "orcid": "0000-0003-0996-1644", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d6abb3fc822a4cacbf1d45224f2442f5.json"}}], "type": "journal article", "published": "2023-06-07", "journal": {"title": "Nat Commun", "issn": "2041-1723", "volume": "14", "issue": "1", "pages": "3280", "issn-l": "2041-1723"}, "abstract": "Venous thromboembolism (VTE) is a common, multi-causal disease with potentially serious short- and long-term complications. In clinical practice, there is a need for improved plasma biomarker-based tools for VTE diagnosis and risk prediction. Here we show, using proteomics profiling to screen plasma from patients with suspected acute VTE, and several case-control studies for VTE, how Complement Factor H Related 5 protein (CFHR5), a regulator of the alternative pathway of complement activation, is a VTE-associated plasma biomarker. In plasma, higher CFHR5 levels are associated with increased thrombin generation potential and recombinant CFHR5 enhanced platelet activation in vitro. GWAS analysis of ~52,000 participants identifies six loci associated with CFHR5 plasma levels, but Mendelian randomization do not demonstrate causality between CFHR5 and VTE. Our results indicate an important role for the regulation of the alternative pathway of complement activation in VTE and that CFHR5 represents a potential diagnostic and/or risk predictive plasma biomarker.", "doi": "10.1038/s41467-023-38383-y", "pmid": "37286573", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC10247781"}, {"db": "pii", "key": "10.1038/s41467-023-38383-y"}], "notes": [], "created": "2026-08-20T08:52:37.351Z", "modified": "2026-08-20T08:52:38.261Z"}, {"entity": "publication", "iuid": "5195ce1c7147434c92ca57f36caec0e0", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/5195ce1c7147434c92ca57f36caec0e0.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/5195ce1c7147434c92ca57f36caec0e0"}}, "title": "Profiles of circulating histidine-rich glycoprotein associate with chronological age and risk of all-cause mortality", "authors": [{"family": "Hong", "given": "Mun Gwan", "initials": "MG", "orcid": "0000-0001-8603-8293", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d12504acae5c4f31b83f75c3d7786cd4.json"}}, {"family": "Dodig-Crnkovi\u0107", "given": "Tea", "initials": "T", "orcid": "0000-0002-2875-896X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5365873ed6a7463485fb44550a4826ec.json"}}, {"family": "Chen", "given": "Xu", "initials": "X", "orcid": "0000-0002-7299-3238", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/a4e440b72e0f47079dadf74bfd661448.json"}}, {"family": "Drobin", "given": "Kimi", "initials": "K"}, {"family": "Lee", "given": "Woojoo", "initials": "W", "orcid": "0000-0001-7447-7045", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c1f336e0cda240838ba0534f3b454121.json"}}, {"family": "Wang", "given": "Yunzhang", "initials": "Y"}, {"family": "Edfors", "given": "Fredrik", "initials": "F"}, {"family": "Kotol", "given": "David", "initials": "D", "orcid": "0000-0002-5388-3826", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c41f8f491c474e6bba2047b5d04b4af5.json"}}, {"family": "Thomas", "given": "Cecilia Engel", "initials": "CE"}, {"family": "Sj\u00f6berg", "given": "Ronald", "initials": "R", "orcid": "0000-0003-1363-5796", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d78ebc1fe5f140dd8a8011d8f7f4d05c.json"}}, {"family": "Odeberg", "given": "Jacob", "initials": "J", "orcid": "0000-0003-0996-1644", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d6abb3fc822a4cacbf1d45224f2442f5.json"}}, {"family": "Hamsten", "given": "Anders", "initials": "A"}, {"family": "Silveira", "given": "Angela", "initials": "A", "orcid": "0000-0003-2063-4935", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/2d8cbafcc7f04ac3adda984af7d85a16.json"}}, {"family": "Hall", "given": "Per", "initials": "P", "orcid": "0000-0002-5640-9126", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d59cc296ca1649ceb0d0734d20f1510a.json"}}, {"family": "Nilsson", "given": "Peter", "initials": "P", "orcid": "0000-0002-4657-8532", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3db33fa3edb94febb8be7927a16838d0.json"}}, {"family": "Pawitan", "given": "Yudi", "initials": "Y", "orcid": "0000-0003-0324-7052", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c45201523b0d47fc9067d3fbe25ffa17.json"}}, {"family": "H\u00e4gg", "given": "Sara", "initials": "S", "orcid": "0000-0002-2452-1500", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/40186021027c42e4b2ed6daf9c196a29.json"}}, {"family": "Uhl\u00e9n", "given": "Mathias", "initials": "M", "orcid": "0000-0002-4858-8056", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9ea446aa574042a295d5f69437402f76.json"}}, {"family": "Pedersen", "given": "Nancy L", "initials": "NL", "orcid": "0000-0001-8057-3543", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/db8023b719d54397bc73a795d4f13381.json"}}, {"family": "Magnusson", "given": "Patrik K E", "initials": "PKE", "orcid": "0000-0002-7315-7899", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/d6fa8b01df9f4bf68607603c51c5a106.json"}}, {"family": "Schwenk", "given": "Jochen M", "initials": "JM", "orcid": "0000-0001-8141-8449", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/022e140799b6466ea123319c3d70c76e.json"}}], "type": "posted-content", "published": "2018-11-09", "journal": {"issn-l": null}, "abstract": null, "doi": "10.1101/464909", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T11:11:26.556Z", "modified": "2026-08-20T11:11:26.834Z"}]}