{"entity": "researcher", "timestamp": "2026-09-25T23:03:50.547Z", "family": "Garma", "given": "Leonardo D", "initials": "LD", "orcid": "0000-0003-1220-8397", "affiliations": ["Karolinska Institutet, Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Stockholm, Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/2b5435eabbd04c53b26b4507574e0d36.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/2b5435eabbd04c53b26b4507574e0d36"}}, "publications": [{"entity": "publication", "iuid": "c1b4eb2ab1224c8b9419423926b771fb", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/c1b4eb2ab1224c8b9419423926b771fb.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/c1b4eb2ab1224c8b9419423926b771fb"}}, "title": "Inkjet-Printed Graphene Multielectrode Arrays: An Accessible Platform for In Vitro Cardiac Electrophysiology.", "authors": [{"family": "Lumpuy-Castillo", "given": "Jairo", "initials": "J"}, {"family": "Fu", "given": "Yujie", "initials": "Y"}, {"family": "Avila Ramirez", "given": "Alan Eduardo", "initials": "AE", "orcid": "0000-0001-9549-1516", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/900a9e8a82fd4708b025f91c613428fe.json"}}, {"family": "Solodka", "given": "Kateryna", "initials": "K"}, {"family": "Li", "given": "Jiantong", "initials": "J", "orcid": "0000-0002-6430-6135", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/fd7a97630a874026aea43d30059b0ef2.json"}}, {"family": "Lorenzo", "given": "Oscar", "initials": "O"}, {"family": "Zeglio", "given": "Erica", "initials": "E"}, {"family": "Garma", "given": "Leonardo D", "initials": "LD", "orcid": "0000-0003-1220-8397", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/2b5435eabbd04c53b26b4507574e0d36.json"}}], "type": "journal article", "published": "2025-05-19", "journal": {"title": "ACS Appl Bio Mater", "issn": "2576-6422", "volume": "8", "issue": "5", "pages": "3708-3716", "issn-l": null}, "abstract": "In vitro models have now become a realistic alternative to animal models for cardiotoxicity assessment. However, the cost and expertise required to implement in vitro electrophysiology systems to study cardiac cells pose a strong obstacle to their widespread use. This study presents a cost-effective approach forin vitro cardiac electrophysiology using fully printed graphene-based microelectrode arrays (pGMEAs) coupled to an open-source signal acquisition system. We characterized the pGMEAs' electrical properties and biocompatibility, observing low impedance values and cell viability. We demonstrated the platform's capability to record spontaneous electrophysiological activity from HL-1 cell cultures, and we monitored and quantified their responses to chemical stimulation with noradrenaline. This study demonstrates the feasibility of producing fully printed graphene-based devices for in vitro electrophysiology. The accessible and versatile platform we present here represents a step further in the development of alternative methods for cardiac safety screening.", "doi": "10.1021/acsabm.4c01677", "pmid": "40285727", "labels": [], "xrefs": [], "notes": [], "created": "2026-09-23T13:23:07.858Z", "modified": "2026-09-23T13:23:07.980Z"}, {"entity": "publication", "iuid": "2d946271275048a7a8bc7d1dac898532", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/2d946271275048a7a8bc7d1dac898532.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/2d946271275048a7a8bc7d1dac898532"}}, "title": "Interneuron diversity in the human dorsal striatum.", "authors": [{"family": "Garma", "given": "Leonardo D", "initials": "LD", "orcid": "0000-0003-1220-8397", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/2b5435eabbd04c53b26b4507574e0d36.json"}}, {"family": "Harder", "given": "Lisbeth", "initials": "L", "orcid": "0000-0002-0637-720X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/681ed4cd72fc41709b33cdcfb30d81e1.json"}}, {"family": "Barba-Reyes", "given": "Juan M", "initials": "JM"}, {"family": "Marco Salas", "given": "Sergio", "initials": "S"}, {"family": "D\u00edez-Salguero", "given": "M\u00f3nica", "initials": "M"}, {"family": "Nilsson", "given": "Mats", "initials": "M", "orcid": "0000-0001-9985-0387", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3311155f09a64b4f88d673da2a40627b.json"}}, {"family": "Serrano-Pozo", "given": "Alberto", "initials": "A", "orcid": "0000-0003-0899-7530", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/30f468ad4acc4fc890841b5d4ac1d3c6.json"}}, {"family": "Hyman", "given": "Bradley T", "initials": "BT", "orcid": "0000-0002-7959-9401", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9c757e4b540d490e80960dca4d90ef5d.json"}}, {"family": "Mu\u00f1oz-Manchado", "given": "Ana B", "initials": "AB", "orcid": "0000-0002-1121-6072", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4bce0de777144d7389fbb29bb3e246bb.json"}}], "type": "journal article", "published": "2024-07-22", "journal": {"title": "Nat Commun", "issn": "2041-1723", "volume": "15", "issue": "1", "pages": "6164", "issn-l": "2041-1723"}, "abstract": "Deciphering the striatal interneuron diversity is key to understanding the basal ganglia circuit and to untangling the complex neurological and psychiatric diseases affecting this brain structure. We performed snRNA-seq and spatial transcriptomics of postmortem human caudate nucleus and putamen samples to elucidate the diversity and abundance of interneuron populations and their inherent transcriptional structure in the human dorsal striatum. We propose a comprehensive taxonomy of striatal interneurons with eight main classes and fourteen subclasses, providing their full transcriptomic identity and spatial expression profile as well as additional quantitative FISH validation for specific populations. We have also delineated the correspondence of our taxonomy with previous standardized classifications and shown the main transcriptomic and class abundance differences between caudate nucleus and putamen. Notably, based on key functional genes such as ion channels and synaptic receptors, we found matching known mouse interneuron populations for the most abundant populations, the recently described PTHLH and TAC3 interneurons. Finally, we were able to integrate other published datasets with ours, supporting the generalizability of this harmonized taxonomy.", "doi": "10.1038/s41467-024-50414-w", "pmid": "39039043", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC11263574"}, {"db": "pii", "key": "10.1038/s41467-024-50414-w"}], "notes": [], "created": "2026-09-23T08:50:16.591Z", "modified": "2026-09-23T08:50:16.786Z"}]}