{"entity": "researcher", "timestamp": "2026-09-30T03:01:02.757Z", "family": "Hovland", "given": "Randi", "initials": "R", "orcid": "0000-0001-8543-2213", "affiliations": ["Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/22091a7272774f44ba2f732fe66be74b.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/22091a7272774f44ba2f732fe66be74b"}}, "publications": [{"entity": "publication", "iuid": "5f2514c6de2f4ec1ba4b3de3d58339db", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/5f2514c6de2f4ec1ba4b3de3d58339db.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/5f2514c6de2f4ec1ba4b3de3d58339db"}}, "title": "Author Correction: Early response evaluation by single cell signaling profiling in acute myeloid leukemia.", "authors": [{"family": "Tislevoll", "given": "Benedicte Sjo", "initials": "BS", "orcid": "0000-0003-4962-997X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/af301fcc03e04fee927f4e3dfdb6f306.json"}}, {"family": "Helles\u00f8y", "given": "Monica", "initials": "M", "orcid": "0000-0002-0115-7427", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/65449b403fe24b85b0b1956e899ee9b8.json"}}, {"family": "Fagerholt", "given": "Oda Helen Eck", "initials": "OHE", "orcid": "0000-0002-5712-8860", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5eecc6379b1c45d6914f476adfcaf6e2.json"}}, {"family": "Gullaksen", "given": "Stein-Erik", "initials": "SE"}, {"family": "Srivastava", "given": "Aashish", "initials": "A", "orcid": "0000-0003-0532-3979", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c0d5e9491f2a45c4bdab026c75952543.json"}}, {"family": "Birkeland", "given": "Even", "initials": "E"}, {"family": 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{"family": "Hovland", "given": "Randi", "initials": "R", "orcid": "0000-0001-8543-2213", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/22091a7272774f44ba2f732fe66be74b.json"}}, {"family": "Andresen", "given": "Vibeke", "initials": "V", "orcid": "0000-0002-2368-2978", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/bcdd2d40b05142298636d61ada2f4683.json"}}, {"family": "Seternes", "given": "Ole Morten", "initials": "OM", "orcid": "0000-0001-8537-3612", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/74056408122f40c08cc691ce3e5bcb5b.json"}}, {"family": "Tvedt", "given": "Tor Henrik Anderson", "initials": "THA"}, {"family": "Aghaeepour", "given": "Nima", "initials": "N", "orcid": "0000-0002-6117-8764", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/6543bf6b62bc4ce09e63a3084d4dd8fc.json"}}, {"family": "Gavasso", "given": "Sonia", "initials": "S"}, {"family": 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"https://publications-affiliated.scilifelab.se/researcher/f98ea8bec56a4f97be30aba956d54f3b.json"}}, {"family": "Gjertsen", "given": "Bj\u00f8rn Tore", "initials": "BT", "orcid": "0000-0001-9358-9704", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/75dad61796ac46c781ba94ddd70a7ff1.json"}}], "type": "published erratum", "published": "2023-03-30", "journal": {"title": "Nat Commun", "issn": "2041-1723", "volume": "14", "issue": "1", "pages": "1767", "issn-l": "2041-1723"}, "abstract": null, "doi": "10.1038/s41467-023-37488-8", "pmid": "36997540", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC10063685"}, {"db": "pii", "key": "10.1038/s41467-023-37488-8"}], "notes": [], "created": "2026-09-23T15:25:06.087Z", "modified": "2026-09-23T15:25:06.233Z"}, {"entity": "publication", "iuid": "f41143a48ac34f0ea350ad96b8e275fe", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/f41143a48ac34f0ea350ad96b8e275fe.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/f41143a48ac34f0ea350ad96b8e275fe"}}, "title": "Early response evaluation by single cell signaling profiling in acute myeloid leukemia.", "authors": [{"family": "Tislevoll", "given": "Benedicte Sjo", "initials": "BS", "orcid": "0000-0003-4962-997X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/af301fcc03e04fee927f4e3dfdb6f306.json"}}, {"family": "Helles\u00f8y", "given": "Monica", "initials": "M", "orcid": "0000-0002-0115-7427", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/65449b403fe24b85b0b1956e899ee9b8.json"}}, {"family": "Fagerholt", "given": "Oda Helen Eck", "initials": "OHE", "orcid": "0000-0002-5712-8860", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5eecc6379b1c45d6914f476adfcaf6e2.json"}}, {"family": "Gullaksen", "given": "Stein-Erik", "initials": "SE"}, {"family": "Srivastava", "given": "Aashish", "initials": "A", "orcid": "0000-0003-0532-3979", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c0d5e9491f2a45c4bdab026c75952543.json"}}, {"family": "Birkeland", "given": "Even", "initials": "E"}, {"family": "Kleftogiannis", "given": "Dimitrios", "initials": "D", "orcid": "0000-0003-1086-821X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/2cc697da7c7842f882d2b6bd82c8fd15.json"}}, {"family": "Ayuda-Dur\u00e1n", "given": "Pilar", "initials": "P", "orcid": "0000-0002-9799-3680", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/27ec4b19ff434960b52ec26245764a14.json"}}, {"family": "Piechaczyk", "given": "Laure", "initials": "L"}, {"family": "Tadele", "given": "Dagim Shiferaw", "initials": "DS", "orcid": "0000-0001-8319-678X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/cba6d806b3d041b985bd7b7c53071566.json"}}, {"family": "Skavland", "given": "J\u00f8rn", "initials": "J"}, {"family": "Baliakas", "given": "Panagotis", "initials": "P", "orcid": "0000-0002-5634-7156", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/2a31997db1ee4ef1aaff75e423b8ccfb.json"}}, {"family": "Hovland", "given": "Randi", "initials": "R", "orcid": "0000-0001-8543-2213", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/22091a7272774f44ba2f732fe66be74b.json"}}, {"family": "Andresen", "given": "Vibeke", "initials": "V", "orcid": "0000-0002-2368-2978", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/bcdd2d40b05142298636d61ada2f4683.json"}}, {"family": "Seternes", "given": "Ole Morten", "initials": "OM", "orcid": "0000-0001-8537-3612", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/74056408122f40c08cc691ce3e5bcb5b.json"}}, {"family": "Tvedt", "given": "Tor Henrik Anderson", "initials": "THA"}, {"family": "Aghaeepour", "given": "Nima", "initials": "N", "orcid": "0000-0002-6117-8764", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/6543bf6b62bc4ce09e63a3084d4dd8fc.json"}}, {"family": "Gavasso", "given": "Sonia", "initials": "S"}, {"family": "Porkka", "given": "Kimmo", "initials": "K", "orcid": "0000-0003-4112-5902", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ca85befea3aa47fcab8cf853c4cf6957.json"}}, {"family": "Jonassen", "given": "Inge", "initials": "I", "orcid": "0000-0003-4110-0748", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9e0d9aacc4404573b3a0fae9aaa0613c.json"}}, {"family": "Fl\u00f8isand", "given": "Yngvar", "initials": "Y", "orcid": "0000-0001-7267-1944", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1d0cd455ed7e41a39a2146a64a403d66.json"}}, {"family": "Enserink", "given": "Jorrit", "initials": "J", "orcid": "0000-0002-2394-5387", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8565d78a1d6c4b2f9fd969c993abdf1d.json"}}, {"family": "Blaser", "given": "Nello", "initials": "N", "orcid": "0000-0001-9489-1657", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f98ea8bec56a4f97be30aba956d54f3b.json"}}, {"family": "Gjertsen", "given": "Bj\u00f8rn Tore", "initials": "BT", "orcid": "0000-0001-9358-9704", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/75dad61796ac46c781ba94ddd70a7ff1.json"}}], "type": "journal article", "published": "2023-01-07", "journal": {"title": "Nat Commun", "issn": "2041-1723", "volume": "14", "issue": "1", "pages": "115", "issn-l": "2041-1723"}, "abstract": "Aberrant pro-survival signaling is a hallmark of cancer cells, but the response to chemotherapy is poorly understood. In this study, we investigate the initial signaling response to standard induction chemotherapy in a cohort of 32 acute myeloid leukemia (AML) patients, using 36-dimensional mass cytometry. Through supervised and unsupervised machine learning approaches, we find that reduction of extracellular-signal-regulated kinase (ERK) 1/2 and p38 mitogen-activated protein kinase (MAPK) phosphorylation in the myeloid cell compartment 24 h post-chemotherapy is a significant predictor of patient 5-year overall survival in this cohort. Validation by RNA sequencing shows induction of MAPK target gene expression in patients with high phospho-ERK1/2 24 h post-chemotherapy, while proteomics confirm an increase of the p38 prime target MAPK activated protein kinase 2 (MAPKAPK2). In this study, we demonstrate that mass cytometry can be a valuable tool for early response evaluation in AML and elucidate the potential of functional signaling analyses in precision oncology diagnostics.", "doi": "10.1038/s41467-022-35624-4", "pmid": "36611026", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC9825407"}, {"db": "pii", "key": "10.1038/s41467-022-35624-4"}], "notes": [], "created": "2026-09-23T09:58:37.965Z", "modified": "2026-09-23T10:35:40.130Z"}]}