{"entity": "researcher", "timestamp": "2026-09-23T21:38:31.568Z", "family": "Potteg\u00e5rd", "given": "A", "initials": "A", "orcid": "0000-0001-9314-5679", "affiliations": ["Clinical Pharmacology and Pharmacy, Department of Public Health, University of Southern Denmark, Odense, Denmark."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/1daf4d9300f94bf6916f968437b52a80.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/1daf4d9300f94bf6916f968437b52a80"}}, "publications": [{"entity": "publication", "iuid": "491a452b3b0646278c44c993d28d3c25", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/491a452b3b0646278c44c993d28d3c25.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/491a452b3b0646278c44c993d28d3c25"}}, "title": "EpiCore-A Common Data Model for Pharmacoepidemiological Studies in Denmark, Norway, and Sweden.", "authors": [{"family": "Jensen", "given": "Peter Bj\u00f8dstrup", "initials": "PB", "orcid": "0000-0001-5435-9092", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/49e53e58a93c4cb49b089964ab105bd9.json"}}, {"family": "Andersen", "given": "Jacob H", "initials": "JH"}, {"family": "Ernst", "given": "Martin Thomsen", "initials": "MT"}, {"family": "Olesen", "given": "Morten", "initials": "M"}, {"family": "Karlstad", "given": "\u00d8ystein", "initials": "\u00d8", "orcid": "0000-0003-1204-787X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/444d55a5814c4342a44da5f6488b6e23.json"}}, {"family": "Furu", "given": "Kari", "initials": "K", "orcid": "0000-0003-2245-0179", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f00c9192b2a642869c13e93ca5526147.json"}}, {"family": "Eriksson", "given": "Julia", "initials": "J"}, {"family": "Gembert", "given": "Karin", "initials": "K"}, {"family": "Potteg\u00e5rd", "given": "Anton", "initials": "A", "orcid": "0000-0001-9314-5679", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1daf4d9300f94bf6916f968437b52a80.json"}}], "type": "journal article", "published": "2025-11-00", "journal": {"title": "Pharmacoepidemiol Drug Saf", "issn": "1099-1557", "volume": "34", "issue": "11", "pages": "e70241", "issn-l": null}, "abstract": "The use of common data models (CDMs) is increasing; however, the complexity of many CDM frameworks constitutes a barrier for their use. For many local and collaborative use cases, simpler CDMs can suffice. Here, we propose the EpiCore CDM, a simple CDM framework for use in Scandinavian pharmacoepidemiological studies.\n\nThe EpiCore CDM was developed based on a set of guiding principles. It should (i) accommodate the most common elements of typical data sources in the field and region, (ii) be accessible to users without needing advanced technical expertise or database infrastructure, (iii) prioritize structural and syntactic harmonization of data and defer clinical concept mapping to the analytical phase, (iv) be usable in both collaborative and single site settings, and (v) include support for quality control procedures.\n\nThe EpiCore CDM comprises two mandatory administrative tables (person and observation), six optional event tables (diagnosis, procedure, encounter, drug, primcare, and cancer) and three optional lookup tables (drug_info, organisation_info, and prescriber_info). Each table, along with its columns and constraints is specified according to an EpiCore CDM specification template. This provides easy documentation and integrates with an R-package called EpiCoreAssistant, which provides quality control tools for testing the compliance of a CDM instance with the EpiCore specification. In the event that a project requires customization of the CDM, this is easily implemented in the template and testing. A step-by-step description is presented, demonstrating the steps involved in a typical CDM-based collaborative pharmacoepidemiological study using the EpiCore CDM.\n\nWe present the EpiCore CDM, a specification template and an R package that offers a simple framework for improved workflows, standardizations and collaboration, focused on Scandinavian pharmacoepidemiological studies and with relevance for a broad palette of register-based health care researchers.", "doi": "10.1002/pds.70241", "pmid": "41185087", "labels": [], "xrefs": [], "notes": [], "created": "2026-09-23T15:52:48.517Z", "modified": "2026-09-23T15:52:48.619Z"}, {"entity": "publication", "iuid": "ba9985751de04ea8bade892117cf7f6e", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/ba9985751de04ea8bade892117cf7f6e.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/ba9985751de04ea8bade892117cf7f6e"}}, "title": "Use of non-insulin antidiabetic drugs in children and young adults - A Scandinavian drug utilization study from 2010-2019.", "authors": [{"family": "Jensen", "given": "Helene K", "initials": "HK", "orcid": "0000-0003-4669-133X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0f2bb5f699f4478db9ee30639f31febb.json"}}, {"family": "Rasmussen", "given": "Lotte", "initials": "L", "orcid": "0000-0001-5962-6647", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b6a270c0d778409dace2e3ff4d7f181b.json"}}, {"family": "Furu", "given": "Kari", "initials": "K"}, {"family": "Karlstad", "given": "\u00d8ystein", "initials": "\u00d8", "orcid": "0000-0003-1204-787X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/444d55a5814c4342a44da5f6488b6e23.json"}}, {"family": "Linder", "given": "Marie", "initials": "M"}, {"family": "Cesta", "given": "Carolyn E", "initials": "CE"}, {"family": "Potteg\u00e5rd", "given": "Anton", "initials": "A", "orcid": "0000-0001-9314-5679", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1daf4d9300f94bf6916f968437b52a80.json"}}], "type": "journal article", "published": "2021-11-00", "journal": {"title": "Br J Clin Pharmacol", "issn": "1365-2125", "volume": "87", "issue": "11", "pages": "4470-4475", "issn-l": null}, "abstract": "Knowledge on utilization patterns of non-insulin antidiabetic drugs in childhood and youth is limited. Therefore, we conducted a population-based drug utilization study using publicly available aggregate data on use of non-insulin antidiabetics from 2010 to 2019 in Scandinavia (Denmark, Norway and Sweden) in individuals aged up to 24 years. For each non-insulin antidiabetic drug, we calculated the annual prevalence proportion of users, overall and for specific age groups. From 2010 to 2019, the prevalence of non-insulin antidiabetic users in Scandinavia increased 37% from 0.43 to 0.59/1000 individuals. The prevalence proportions were highest among female adolescents and young adults, but the largest relative increase in use was seen among 10-14-year-olds (78%). Metformin was by far the most widely used non-insulin antidiabetic drug with a prevalence proportion of 0.51/1000 in 2019, followed by glucagon-like peptide-1 (GLP-1) analogues, which, however, showed an eight-fold relative increase during the study period.", "doi": "10.1111/bcp.14867", "pmid": "33871080", "labels": [], "xrefs": [], "notes": [], "created": "2026-09-23T13:11:05.971Z", "modified": "2026-09-23T13:11:06.119Z"}, {"entity": "publication", "iuid": "7082e012404d45b18ee84d3636cd7299", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/7082e012404d45b18ee84d3636cd7299.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/7082e012404d45b18ee84d3636cd7299"}}, "title": "Use of hypnotic drugs among children, adolescents, and young adults in Scandinavia.", "authors": [{"family": "Wesselhoeft", "given": "Rikke", "initials": "R", "orcid": "0000-0001-9700-2739", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/29670ecb185844689260deb334d8ef10.json"}}, {"family": "Rasmussen", "given": "Lotte", "initials": "L"}, {"family": "Jensen", "given": "Peter Bj\u00f8dstrup", "initials": "PB"}, {"family": "Jennum", "given": "Poul J\u00f8rgen", "initials": "PJ", "orcid": "0000-0001-6986-5254", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/01b009348f0846beb1d0c60941b1ca28.json"}}, {"family": "Skurtveit", "given": "Svetlana", "initials": "S"}, {"family": "Hartz", "given": "Ingeborg", "initials": "I"}, {"family": "Reutfors", "given": "Johan", "initials": "J", "orcid": "0000-0003-1372-4262", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/dbc162955acf4b2ba0b4dade363d4592.json"}}, {"family": "Damkier", "given": "Per", "initials": "P", "orcid": "0000-0003-0591-7187", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3220b6c562f2497f9122594f270ba2ab.json"}}, {"family": "Bliddal", "given": "Mette", "initials": "M"}, {"family": "Potteg\u00e5rd", "given": "Anton", "initials": "A", "orcid": "0000-0001-9314-5679", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1daf4d9300f94bf6916f968437b52a80.json"}}], "type": "journal article", "published": "2021-08-00", "journal": {"title": "Acta Psychiatr Scand", "issn": "1600-0447", "volume": "144", "issue": "2", "pages": "100-112", "issn-l": null}, "abstract": "Hypnotic use in children and adolescents is controversial.\n\nTo describe the use of hypnotic drugs (melatonin, z-drugs, and sedating antihistamines) among 5- to 24-year-old Scandinavians during 2012 to 2018.\n\nAggregate-level data were obtained from public data sources in Sweden, Norway, and Denmark. We calculated annual prevalence (users/1000 inhabitants) stratified by age group, sex, and country. Quantity of use (Defined Daily Dose (DDD)/user/day) was estimated for Norway and Denmark.\n\nMelatonin was the most commonly used hypnotic, and its use increased markedly from 2012 to 2018, particularly among females and 15- to 24-year-old individuals. Sweden had the highest increase in use (6.5 to 25/1000) compared with Norway (10-20/1000) and Denmark (5.7-12/1000). The annual prevalence of sedating antihistamine use was also highest in Sweden, reaching 13/1000 in 2018 in comparison to 7.5/1000 in Norway and 2.5/1000 in Denmark. Z-drug use decreased in all countries toward 2018, dropping to 3.5/1000 in Sweden, 4.4/1000 in Norway, and 1.7/1000 in Denmark. The quantity of hypnotic use in Norway and Denmark was 0.8-1.0 DDD/user/day for melatonin in 2018, as compared to 0.1-0.3 for z-drugs and antihistamines.\n\nThe use of melatonin and sedating antihistamines increased among young Scandinavians during 2012-2018, and the increase was twice as high in Sweden compared with Norway and Denmark. In addition, Sweden had the highest use of sedating antihistamines. The Scandinavian variation of hypnotic use could reflect differences in frequency of sleep problems between populations or variation of healthcare access or clinical practice between countries.", "doi": "10.1111/acps.13329", "pmid": "34021908", "labels": [], "xrefs": [], "notes": [], "created": "2026-09-23T09:59:52.674Z", "modified": "2026-09-23T10:37:29.122Z"}, {"entity": "publication", "iuid": "50017f7dc1534a7bb3cb353746fa8c43", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/50017f7dc1534a7bb3cb353746fa8c43.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/50017f7dc1534a7bb3cb353746fa8c43"}}, "title": "Trends in antidepressant use among children and adolescents: a Scandinavian drug utilization study.", "authors": [{"family": "Wesselhoeft", "given": "R", "initials": "R", "orcid": "0000-0001-9700-2739", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/29670ecb185844689260deb334d8ef10.json"}}, {"family": "Jensen", "given": "P B", "initials": "PB"}, {"family": "Talati", "given": "A", "initials": "A"}, {"family": "Reutfors", "given": "J", "initials": "J"}, {"family": "Furu", "given": "K", "initials": "K"}, {"family": "Strandberg-Larsen", "given": "K", "initials": "K"}, {"family": "Damkier", "given": "P", "initials": "P", "orcid": "0000-0003-0591-7187", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3220b6c562f2497f9122594f270ba2ab.json"}}, {"family": "Potteg\u00e5rd", "given": "A", "initials": "A", "orcid": "0000-0001-9314-5679", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1daf4d9300f94bf6916f968437b52a80.json"}}, {"family": "Bliddal", "given": "M", "initials": "M"}], "type": "journal article", "published": "2020-01-00", "journal": {"title": "Acta Psychiatr Scand", "issn": "1600-0447", "volume": "141", "issue": "1", "pages": "34-42", "issn-l": null}, "abstract": "To compare antidepressant utilization in individuals aged 5-19 years from the Scandinavian countries.\n\nA population-based drug utilization study using publicly available data of antidepressant use from Denmark, Norway, and Sweden.\n\nIn the study period from 2007 to 2017, the proportion of antidepressant users increased markedly in Sweden (9.3-18.0/1000) compared to Norway (5.1-7.6/1000) and Denmark (9.3-7.5/1000). In 2017, the cumulated defined daily doses (DDD) of selective serotonin reuptake inhibitors were 5611/1000 inhabitants in Sweden, 2709/1000 in Denmark, and 1848/1000 in Norway. The use of 'other antidepressants' (ATC code N06AX) also increased in Sweden with a higher DDD in 2017 (497/1000) compared to Denmark (225/1000) and Norway (170/1000). The use of tricyclic antidepressants was generally low in 2017 with DDDs ranging between 30-42 per 1000. The proportion of antidepressant users was highest among 15- to 19-year-old individuals. Girls were more likely to receive treatment than boys, and the treated female/male ratios per 1000 were similar in Sweden (2.39), Denmark (2.44), and Norway (2.63).\n\nEven in highly comparable healthcare systems like the Scandinavian countries', variation in antidepressant use is considerable. Swedish children and adolescents have a markedly higher and still increasing use of antidepressants compared to Danish and Norwegian peers.", "doi": "10.1111/acps.13116", "pmid": "31618447", "labels": [], "xrefs": [], "notes": [], "created": "2026-09-23T08:43:15.599Z", "modified": "2026-09-23T08:43:15.848Z"}]}