{"entity": "researcher", "timestamp": "2026-09-25T23:05:21.740Z", "family": "Mayer", "given": "Philipp", "initials": "P", "orcid": "0000-0001-5138-7506", "affiliations": ["Department of Environmental and Resource Engineering, Technical University of Denmark, Kgs. Lyngby 2800, Denmark."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/1bcee11616a840e5a5a6975846947c3e.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/1bcee11616a840e5a5a6975846947c3e"}}, "publications": [{"entity": "publication", "iuid": "ba1ff7715d26412b9028fbb7b24f937f", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/ba1ff7715d26412b9028fbb7b24f937f.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/ba1ff7715d26412b9028fbb7b24f937f"}}, "title": "Persistence-Directed Testing of Chemicals Discharged from Offshore Oil Platforms Combined with Nontargeted Analysis.", "authors": [{"family": "M\u00f8ller", "given": "Mette T", "initials": "MT", "orcid": "0000-0003-2216-6514", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9cd9bf01904840489b191f839a4dedc6.json"}}, {"family": "Birch", "given": "Heidi", "initials": "H", "orcid": "0000-0002-7152-3832", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9476246b77f64af7a0cbccbd38db802b.json"}}, {"family": "Sj\u00f8holm", "given": "Karina K", "initials": "KK", "orcid": "0000-0002-2964-3849", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c8a5cae445d04010a0dac030c30ef5af.json"}}, {"family": "Papazian", "given": "Stefano", "initials": "S", "orcid": "0000-0003-2538-8702", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/27c56d6b160c42d4b3782d78210e80ff.json"}}, {"family": "Wennberg", "given": "Aina C", "initials": "AC", "orcid": "0000-0003-3798-6574", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ed0d951fb6a54173a2d453cb55291817.json"}}, {"family": "Bonnefille", "given": "B\u00e9nilde", "initials": "B", "orcid": "0000-0001-5141-7111", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8df2bdf31f21411a90ccc2f9bb6eaf10.json"}}, {"family": "Kronsbein", "given": "Pia M", "initials": "PM"}, {"family": "Kelland", "given": "Malcolm A", "initials": "MA", "orcid": "0000-0003-2295-5804", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/70869324a79446d58eaf1519539a0940.json"}}, {"family": "Martin", "given": "Jonathan W", "initials": "JW", "orcid": "0000-0001-6265-4294", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/02199c0d99674e2ea5e96e6589c07a00.json"}}, {"family": "Mayer", "given": "Philipp", "initials": "P", "orcid": "0000-0001-5138-7506", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1bcee11616a840e5a5a6975846947c3e.json"}}], "type": "journal article", "published": "2025-11-11", "journal": {"title": "Environ. Sci. Technol.", "issn": "1520-5851", "volume": "59", "issue": "44", "pages": "24000-24011", "issn-l": "0013-936X"}, "abstract": "Persistent chemicals discharged into the sea can pose long-term, irreversible risks. New approaches are needed to elucidate the number and type of persistent chemicals, particularly in complex mixtures and high-volume discharges. We introduce a novel \"Persistence-Directed Testing\" approach that combines environmentally relevant biodegradation tests with nontarget analytical methods. Complex produced waters from two offshore oil platforms in the North Sea served as case studies. In the biodegradation tests, produced waters were diluted 1:200 with seawater from the site of discharge (inoculum). Biotic test systems and abiotic controls were incubated at 9 \u00b0C. At day 60 nontarget analyses were performed by Solid Phase Microextraction coupled to GC-MS and Solid Phase Extraction coupled to LC-HRMS. Primary biodegradation and persistence were determined based on biotic/abiotic peak area ratios. Over 600 chemicals passed the quality control filtering criteria, and the persistent fraction of chemicals discovered by GC-MS was 4% and that discovered by LC-HRMS was 32-44%. Spectral library matches and computational modeling of the LC-HRMS data annotated several persistent chemicals as N-substituted aromatic ring structures. These findings demonstrate the value of a persistence-directed approach in uncovering the hidden burden of unidentified persistent chemicals in environmental discharges and highlight the urgent need for enhanced treatment of produced water discharges.", "doi": "10.1021/acs.est.5c08802", "pmid": "41160886", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC12613808"}], "notes": [], "created": "2026-09-23T11:38:30.320Z", "modified": "2026-09-23T11:38:30.711Z"}, {"entity": "publication", "iuid": "fa191e4f37f242b8aa0c7b15a416b02c", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/fa191e4f37f242b8aa0c7b15a416b02c.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/fa191e4f37f242b8aa0c7b15a416b02c"}}, "title": "Determining Marine Biodegradation Kinetics of Chemicals Discharged from Offshore Oil Platforms\u2500Whole Mixture Testing at High Dilutions Increases Environmental Relevance.", "authors": [{"family": "M\u00f8ller", "given": "Mette T", "initials": "MT"}, {"family": "Birch", "given": "Heidi", "initials": "H", "orcid": "0000-0002-7152-3832", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9476246b77f64af7a0cbccbd38db802b.json"}}, {"family": "Sj\u00f8holm", "given": "Karina K", "initials": "KK", "orcid": "0000-0002-2964-3849", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c8a5cae445d04010a0dac030c30ef5af.json"}}, {"family": "Skjolding", "given": "Lars M", "initials": "LM"}, {"family": "Xie", "given": "Hongyu", "initials": "H", "orcid": "0000-0002-2422-0492", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/871a1de2d146412693d3cfea85e8e293.json"}}, {"family": "Papazian", "given": "Stefano", "initials": "S", "orcid": "0000-0003-2538-8702", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/27c56d6b160c42d4b3782d78210e80ff.json"}}, {"family": "Mayer", "given": "Philipp", "initials": "P", "orcid": "0000-0001-5138-7506", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1bcee11616a840e5a5a6975846947c3e.json"}}], "type": "journal article", "published": "2024-10-01", "journal": {"title": "Environ. Sci. Technol.", "issn": "1520-5851", "volume": "58", "issue": "39", "pages": "17454-17463", "issn-l": "0013-936X"}, "abstract": "Offshore oil platforms discharge enormous volumes of produced water that contain mixtures of petrochemicals and production chemicals. It is crucial to avoid the discharge of particularly those chemicals that are persistent in the marine environment. This study aims to (1) develop a biodegradation testing approach for discharged chemicals by native marine microorganism, (2) determine how dilution affects biodegradation, and (3) determine biodegradation kinetics for many discharged chemicals at low and noninhibitory concentrations. Produced water from an offshore oil platform was diluted in the ratio of 1:20, 1:60, and 1:200 in seawater from the same location and incubated for 60 days at 10 \u00b0C. Automated solid-phase microextraction GC-MS was used as a sensitive analytical technique, and chemical-specific primary degradation was determined based on peak area ratios between biotic test systems and abiotic controls. Biodegradation was inhibited at lower dilutions, consistent with ecotoxicity tests. Biodegradation kinetics were determined at the highest dilution for 139 chemicals (43 tentatively identified), and 6 chemicals were found persistent (half-life >60 days). Nontargeted analysis by liquid chromatography-high-resolution MS was demonstrated as a proof-of-principle for a comprehensive assessment. Biodegradation testing of chemicals in discharges provides the possibility to assess hundreds of chemicals at once and find the persistent ones.", "doi": "10.1021/acs.est.4c05692", "pmid": "39292649", "labels": [], "xrefs": [], "notes": [], "created": "2026-09-23T12:59:54.303Z", "modified": "2026-09-23T12:59:54.414Z"}]}