{"entity": "researcher", "timestamp": "2026-08-20T20:50:55.438Z", "family": "Tamarit", "given": "Daniel", "initials": "D", "orcid": "0000-0002-4940-719X", "affiliations": ["Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.", "Laboratory of Microbiology, Wageningen University and Research, Wageningen, The Netherlands.", "Department of Aquatic Sciences and Assessment, Swedish University of Agricultural Sciences, Uppsala, Sweden.", "Theoretical Biology and Bioinformatics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, The Netherlands."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/1bc6a5827d7147e097a520745682be8c.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/1bc6a5827d7147e097a520745682be8c"}}, "publications": [{"entity": "publication", "iuid": "2a7dcd6e60e540bbb9fac21491504095", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/2a7dcd6e60e540bbb9fac21491504095.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/2a7dcd6e60e540bbb9fac21491504095"}}, "title": "Inference and reconstruction of the heimdallarchaeial ancestry of eukaryotes.", "authors": [{"family": "Eme", "given": "Laura", "initials": "L", "orcid": "0000-0002-0510-8868", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/bcca924f04e04ac3a760c09c432064df.json"}}, {"family": "Tamarit", "given": "Daniel", "initials": "D", "orcid": "0000-0002-4940-719X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1bc6a5827d7147e097a520745682be8c.json"}}, {"family": "Caceres", "given": "Eva F", "initials": "EF"}, {"family": "Stairs", "given": "Courtney W", "initials": "CW", "orcid": "0000-0001-6650-0970", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ed32f30aa29e4279aef72aed502d2a95.json"}}, {"family": "De Anda", "given": "Valerie", "initials": "V", "orcid": "0000-0001-9775-0737", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/df727714b28e4553bcd94b9d7efbac9a.json"}}, {"family": "Sch\u00f6n", "given": "Max E", "initials": "ME", "orcid": "0000-0002-4453-4173", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/a439173e8ce64fcfb4d09e457f1c6bec.json"}}, {"family": "Seitz", "given": "Kiley W", "initials": "KW"}, {"family": "Dombrowski", "given": "Nina", "initials": "N"}, {"family": "Lewis", "given": "William H", "initials": "WH"}, {"family": "Homa", "given": "Felix", "initials": "F"}, {"family": "Saw", "given": "Jimmy H", "initials": "JH", "orcid": "0000-0001-8353-3854", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ac622e15330648f4a026e35fabb1ad3d.json"}}, {"family": "Lombard", "given": "Jonathan", "initials": "J"}, {"family": "Nunoura", "given": "Takuro", "initials": "T", "orcid": "0000-0003-2323-0880", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/a5736cdecf8d48e99ee03b1034eed980.json"}}, {"family": "Li", "given": "Wen-Jun", "initials": "WJ", "orcid": "0000-0002-1233-736X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/2c043ef2848d4f8e92879fcad2fce271.json"}}, {"family": "Hua", "given": "Zheng-Shuang", "initials": "ZS", "orcid": "0000-0002-2405-4228", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/677936d7c2be4b379391162c834bcbba.json"}}, {"family": "Chen", "given": "Lin-Xing", "initials": "LX"}, {"family": "Banfield", "given": "Jillian F", "initials": "JF", "orcid": "0000-0001-8203-8771", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/89360f8afd6b47f7a6bb6563931f09f3.json"}}, {"family": "John", "given": "Emily St", "initials": "ES", "orcid": "0000-0002-8527-2333", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/a400b0451c6d42b7bcee8a9a8a72a5fe.json"}}, {"family": "Reysenbach", "given": "Anna-Louise", "initials": "AL"}, {"family": "Stott", "given": "Matthew B", "initials": "MB", "orcid": "0000-0002-2082-9460", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1950d073e32b4c3780950608912f090c.json"}}, {"family": "Schramm", "given": "Andreas", "initials": "A", "orcid": "0000-0002-7614-9616", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9333862fcd374edaa6ab11e4f86861a8.json"}}, {"family": "Kjeldsen", "given": "Kasper U", "initials": "KU"}, {"family": "Teske", "given": "Andreas P", "initials": "AP", "orcid": "0000-0003-3669-5425", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/a398b77213244a3b882ae54f0e4ceadc.json"}}, {"family": "Baker", "given": "Brett J", "initials": "BJ", "orcid": "0000-0002-5971-1021", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8ab4c2edccc74d278c7dee4e938a80c3.json"}}, {"family": "Ettema", "given": "Thijs J G", "initials": "TJG", "orcid": "0000-0002-6898-6377", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/6a7921cec2bb45a7a7b0454f41b5f1aa.json"}}], "type": "journal article", "published": "2023-06-00", "journal": {"title": "Nature", "issn": "1476-4687", "volume": "618", "issue": "7967", "pages": "992-999", "issn-l": "0028-0836"}, "abstract": "In the ongoing debates about eukaryogenesis-the series of evolutionary events leading to the emergence of the eukaryotic cell from prokaryotic ancestors-members of the Asgard archaea play a key part as the closest archaeal relatives of eukaryotes1. However, the nature and phylogenetic identity of the last common ancestor of Asgard archaea and eukaryotes remain unresolved2-4. Here we analyse distinct phylogenetic marker datasets of an expanded genomic sampling of Asgard archaea and evaluate competing evolutionary scenarios using state-of-the-art phylogenomic approaches. We find that eukaryotes are placed, with high confidence, as a well-nested clade within Asgard archaea and as a sister lineage to Hodarchaeales, a newly proposed order within Heimdallarchaeia. Using sophisticated gene tree and species tree reconciliation approaches, we show that analogous to the evolution of eukaryotic genomes, genome evolution in Asgard archaea involved significantly more gene duplication and fewer gene loss events compared with other archaea. Finally, we infer that the last common ancestor of Asgard archaea was probably a thermophilic chemolithotroph and that the lineage from which eukaryotes evolved adapted to mesophilic conditions and acquired the genetic potential to support a heterotrophic lifestyle. Our work provides key insights into the prokaryote-to-eukaryote transition and a platform for better understanding the emergence of cellular complexity in eukaryotic cells.", "doi": "10.1038/s41586-023-06186-2", "pmid": "37316666", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC10307638"}, {"db": "pii", "key": "10.1038/s41586-023-06186-2"}], "notes": [], "created": "2026-08-20T08:58:38.192Z", "modified": "2026-08-20T08:58:38.745Z"}, {"entity": "publication", "iuid": "c8f46e1c090a477882811bdc5543949a", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/c8f46e1c090a477882811bdc5543949a.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/c8f46e1c090a477882811bdc5543949a"}}, "title": "Chlamydial contribution to anaerobic metabolism during eukaryotic evolution.", "authors": [{"family": "Stairs", "given": "Courtney W", "initials": "CW", "orcid": "0000-0001-6650-0970", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ed32f30aa29e4279aef72aed502d2a95.json"}}, {"family": "Dharamshi", "given": "Jennah E", "initials": "JE", "orcid": "0000-0003-4563-3939", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b742e97795a94ac99217930b27640e3a.json"}}, {"family": "Tamarit", "given": "Daniel", "initials": "D", "orcid": "0000-0002-4940-719X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1bc6a5827d7147e097a520745682be8c.json"}}, {"family": "Eme", "given": "Laura", "initials": "L", "orcid": "0000-0002-0510-8868", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/bcca924f04e04ac3a760c09c432064df.json"}}, {"family": "J\u00f8rgensen", "given": "Steffen L", "initials": "SL", "orcid": "0000-0003-0240-7907", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5e230b212e5248099306b14bc3cedd82.json"}}, {"family": "Spang", "given": "Anja", "initials": "A", "orcid": "0000-0002-6518-8556", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ee19a6765cb847caac5c440aeb15b509.json"}}, {"family": "Ettema", "given": "Thijs J G", "initials": "TJG", "orcid": "0000-0002-6898-6377", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/6a7921cec2bb45a7a7b0454f41b5f1aa.json"}}], "type": "journal article", "published": "2020-08-00", "journal": {"title": "Sci Adv", "issn": "2375-2548", "volume": "6", "issue": "35", "pages": "eabb7258", "issn-l": "2375-2548"}, "abstract": "The origin of eukaryotes is a major open question in evolutionary biology. Multiple hypotheses posit that eukaryotes likely evolved from a syntrophic relationship between an archaeon and an alphaproteobacterium based on H2 exchange. However, there are no strong indications that modern eukaryotic H2 metabolism originated from archaea or alphaproteobacteria. Here, we present evidence for the origin of H2 metabolism genes in eukaryotes from an ancestor of the Anoxychlamydiales-a group of anaerobic chlamydiae, newly described here, from marine sediments. Among Chlamydiae, these bacteria uniquely encode genes for H2 metabolism and other anaerobiosis-associated pathways. Phylogenetic analyses of several components of H2 metabolism reveal that Anoxychlamydiales homologs are the closest relatives to eukaryotic sequences. We propose that an ancestor of the Anoxychlamydiales contributed these key genes during the evolution of eukaryotes, supporting a mosaic evolutionary origin of eukaryotic metabolism.", "doi": "10.1126/sciadv.abb7258", "pmid": "32923644", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC7449678"}, {"db": "pii", "key": "abb7258"}, {"db": "figshare", "key": "10.6084/m9.figshare.12387980"}], "notes": [], "created": "2026-08-20T11:58:33.078Z", "modified": "2026-08-20T11:58:33.306Z"}]}