{"entity": "researcher", "timestamp": "2026-09-26T23:56:41.573Z", "family": "Vogel", "given": "Ida", "initials": "I", "orcid": "0000-0002-1125-0393", "affiliations": ["Center for Fetal Diagnostics, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.", "Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/155fd724871e4117bb9696a993ba9209.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/155fd724871e4117bb9696a993ba9209"}}, "publications": [{"entity": "publication", "iuid": "b0f163c4c2644abcba8ba0f8e72b6095", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/b0f163c4c2644abcba8ba0f8e72b6095.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/b0f163c4c2644abcba8ba0f8e72b6095"}}, "title": "Factors that impact on women's decision-making around prenatal genomic tests: An international discrete choice survey.", "authors": [{"family": "Buchanan", "given": "James", "initials": "J", "orcid": "0000-0002-6285-2028", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/576cd96c41d74874ab2c58b5f850b9e2.json"}}, {"family": "Hill", "given": "Melissa", "initials": "M", "orcid": "0000-0003-3900-1425", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/e21ffa87962d48d5a350d43301d20c42.json"}}, {"family": "Vass", "given": "Caroline M", "initials": "CM", "orcid": "0000-0002-6385-2812", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b500862fff1d4df29c952cec3c8ac8ce.json"}}, {"family": "Hammond", "given": "Jennifer", "initials": "J", "orcid": "0000-0002-2637-5818", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/582c6cd07232495899bc3a9c3febb173.json"}}, {"family": "Riedijk", "given": "Sam", "initials": "S", "orcid": "0000-0003-3400-4969", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4080c929c2ea44138c93e55e0ffb191b.json"}}, {"family": "Klapwijk", "given": "Jasmijn E", "initials": "JE", "orcid": "0000-0002-6775-6561", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/22bd88fea402453db4e975e0085c902f.json"}}, {"family": "Harding", "given": "Eleanor", "initials": "E"}, {"family": "Lou", "given": "Stina", "initials": "S", "orcid": "0000-0001-6177-5780", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/fb06bbdb35b14f0899410cac88f2d1bd.json"}}, {"family": "Vogel", "given": "Ida", "initials": "I", "orcid": "0000-0002-1125-0393", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/155fd724871e4117bb9696a993ba9209.json"}}, {"family": "Hui", "given": "Lisa", "initials": "L", "orcid": "0000-0002-9720-3562", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/97eb2b74c30a4cdc84cc74f61a8e195a.json"}}, {"family": "Ingvoldstad-Malmgren", "given": "Charlotta", "initials": "C", "orcid": "0000-0003-1915-2453", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b16acdb5c5ba4aedb5a3dab578722ee9.json"}}, {"family": "Soller", "given": "Maria Johansson", "initials": "MJ", "orcid": "0000-0001-9980-8971", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b279540f951a4e088fc659a388d46225.json"}}, {"family": "Ormond", "given": "Kelly E", "initials": "KE", "orcid": "0000-0002-1033-0818", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4c9f40c3c064469f8564ca944ad1d810.json"}}, {"family": "Choolani", "given": "Mahesh", "initials": "M", "orcid": "0000-0001-8336-0973", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b1ab3153908f403cb51c954b1332b214.json"}}, {"family": "Zheng", "given": "Qian", "initials": "Q"}, {"family": "Chitty", "given": "Lyn S", "initials": "LS", "orcid": "0000-0002-4857-7138", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/451e184e4af64d0988a537bb66d8d4d0.json"}}, {"family": "Lewis", "given": "Celine", "initials": "C", "orcid": "0000-0001-7169-1521", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/6a5b0224e38a4613bf20e174c2e16363.json"}}], "type": "journal article", "published": "2022-06-00", "journal": {"title": "Prenat. Diagn.", "issn": "1097-0223", "volume": "42", "issue": "7", "pages": "934-946", "issn-l": "0197-3851"}, "abstract": "We conducted a survey-based discrete-choice experiment (DCE) to understand the test features that drive women's preferences for prenatal genomic testing, and explore variation across countries.\n\nFive test attributes were identified as being important for decision-making through a literature review, qualitative interviews and quantitative scoring exercise. Twelve scenarios were constructed in which respondents choose between two invasive tests or no test. Women from eight countries who delivered a baby in the previous 24 months completed a DCE presenting these scenarios. Choices were modeled using conditional logit regression analysis.\n\nSurveys from 1239 women (Australia: n = 178; China: n = 179; Denmark: n = 88; Netherlands: n = 177; Singapore: n = 90; Sweden: n = 178; UK: n = 174; USA: n = 175) were analyzed. The key attribute affecting preferences was a test with the highest diagnostic yield (p < 0.01). Women preferred tests with short turnaround times (p < 0.01), and tests reporting variants of uncertain significance (VUS; p < 0.01) and secondary findings (SFs; p < 0.01). Several country-specific differences were identified, including time to get a result, who explains the result, and the return of VUS and SFs.\n\nMost women want maximum information from prenatal genomic tests, but our findings highlight country-based differences. Global consensus on how to return uncertain results is not necessarily realistic or desirable.", "doi": "10.1002/pd.6159", "pmid": "35476801", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC9325352"}], "notes": [], "created": "2026-09-23T12:01:26.960Z", "modified": "2026-09-23T12:01:27.613Z"}]}