{"entity": "researcher", "timestamp": "2026-08-20T20:41:13.320Z", "family": "Stoimenov", "given": "Ivaylo", "initials": "I", "orcid": "0000-0002-2133-7396", "affiliations": ["Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/10ad1a77c6f241418187734e9a47c16c.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/10ad1a77c6f241418187734e9a47c16c"}}, "publications": [{"entity": "publication", "iuid": "4169939771554f4689b01d54aee78cfc", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/4169939771554f4689b01d54aee78cfc.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/4169939771554f4689b01d54aee78cfc"}}, "title": "Rigorous software pipeline for clinical somatic mutation analyses of solid tumors", "authors": [{"family": "Stoimenov", "given": "Ivaylo", "initials": "I", "orcid": "0000-0002-2133-7396", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/10ad1a77c6f241418187734e9a47c16c.json"}}, {"family": "Rashyna", "given": "Marina", "initials": "M"}, {"family": "Adlerteg", "given": "Tom", "initials": "T"}, {"family": "Nunes", "given": "Lu\u00eds", "initials": "L", "orcid": "0000-0002-3391-1607", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7aa31ccf1801456bb57744978bd605fd.json"}}, {"family": "Ekstr\u00f6m", "given": "Joakim", "initials": "J", "orcid": "0000-0002-9734-3979", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b217a0aef38c4eb7a84bfc11a90d9d99.json"}}, {"family": "Ljungstr\u00f6m", "given": "Viktor", "initials": "V"}, {"family": "Mathot", "given": "Lucy", "initials": "L", "orcid": "0000-0002-2990-2038", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/458c07a1748d4ce0ac5cff3d6836f350.json"}}, {"family": "Cheong", "given": "Ian", "initials": "I", "orcid": "0000-0002-3062-6878", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/cb36663a59a34099b4c41c8911b8e8f5.json"}}, {"family": "Sj\u00f6blom", "given": "Tobias", "initials": "T", "orcid": "0000-0001-6668-4140", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/851b95a56b3244fb9bc7cec8294e7ae7.json"}}], "type": "posted-content", "published": "2023-06-14", "journal": {"issn-l": null}, "abstract": null, "doi": "10.1101/2023.06.08.23291143", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T10:46:29.849Z", "modified": "2026-08-20T10:46:29.996Z"}, {"entity": "publication", "iuid": "eaeb311846cd44cb87eac4d2b38a84c0", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/eaeb311846cd44cb87eac4d2b38a84c0.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/eaeb311846cd44cb87eac4d2b38a84c0"}}, "title": "Targeting tumor vulnerabilities associated with loss of heterozygosity.", "authors": [{"family": "Rendo", "given": "Veronica", "initials": "V", "orcid": "0000-0002-2983-4020", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9c4c9ca49eb64227be6574a4384ffb46.json"}}, {"family": "Stoimenov", "given": "Ivaylo", "initials": "I", "orcid": "0000-0002-2133-7396", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/10ad1a77c6f241418187734e9a47c16c.json"}}, {"family": "Sj\u00f6blom", "given": "Tobias", "initials": "T"}], "type": "journal article", "published": "2020-05-13", "journal": {"title": "Mol Cell Oncol", "issn": "2372-3556", "volume": "7", "issue": "4", "pages": "1759390", "issn-l": null}, "abstract": "We show that N-acetyltransferase 2 (NAT2) loss of heterozygosity can be targeted in >4% of colorectal cancers with the use of a small molecule. We identify and describe the effect of a compound that impairs the growth of colorectal tumors with slow NAT2 activity by half when compared to wild-type.", "doi": "10.1080/23723556.2020.1759390", "pmid": "32944621", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC7469497"}, {"db": "pii", "key": "1759390"}], "notes": [], "created": "2026-08-20T09:37:51.051Z", "modified": "2026-08-20T09:37:51.114Z"}]}