{"entity": "researcher", "timestamp": "2026-08-20T21:01:27.033Z", "family": "Byberg", "given": "Liisa", "initials": "L", "orcid": "0000-0002-4421-6466", "affiliations": ["Medical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden."], "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/researcher/079e2e50ce7a4bc8ae14ecf7512a415d.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/researcher/079e2e50ce7a4bc8ae14ecf7512a415d"}}, "publications": [{"entity": "publication", "iuid": "909d30e2c6c24070928df7138071fa91", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/909d30e2c6c24070928df7138071fa91.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/909d30e2c6c24070928df7138071fa91"}}, "title": "Major cardiovascular events and death in parents of children with type 1 diabetes: a register-based matched cohort study in Sweden.", "authors": [{"family": "Kennedy", "given": "Beatrice", "initials": "B", "orcid": "0000-0002-0066-4814", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/cb88fcd6bead49978b129dffe779d8a0.json"}}, {"family": "Wernroth", "given": "Mona-Lisa", "initials": "ML", "orcid": "0000-0002-8845-8846", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/228e6d16e2e44389b0dc548584616a70.json"}}, {"family": "Batra", "given": "Gorav", "initials": "G", "orcid": "0000-0002-2480-9547", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/39554aefe1494e3389140d3dbee4ffa9.json"}}, {"family": "Hammar", "given": "Ulf", "initials": "U", "orcid": "0000-0001-8367-5000", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b833fa7c77f542aabd5b04f4d9c02afd.json"}}, {"family": "Linroth", "given": "Cecilia", "initials": "C", "orcid": "0009-0005-3308-9886", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b35ee5eda63444448e0e790c21ac8d5d.json"}}, {"family": "Gr\u00f6nberg", "given": "Annika", "initials": "A", "orcid": "0000-0002-8502-8568", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0442565cd22a4d2e917c8649acc659da.json"}}, {"family": "Byberg", "given": "Liisa", "initials": "L", "orcid": "0000-0002-4421-6466", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/079e2e50ce7a4bc8ae14ecf7512a415d.json"}}, {"family": "Fall", "given": "Tove", "initials": "T", "orcid": "0000-0003-2071-5866", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7dbbd468e6da4727b69333ade942c071.json"}}], "type": "journal article", "published": "2024-09-00", "journal": {"title": "Diabetologia", "issn": "1432-0428", "volume": "67", "issue": "9", "pages": "1828-1837", "issn-l": "0012-186X"}, "abstract": "Parenting a child with type 1 diabetes has been associated with stress-related symptoms. This study aimed to elucidate the potential impact on parental risk of major cardiovascular events (MCE) and death.\n\nIn this register-based study, we included the parents of 18,871 children, born 1987-2020 and diagnosed with type 1 diabetes in Sweden at <18 years. The median parental age at the child's diagnosis was 39.0 and 41.0 years for mothers and fathers, respectively. The cohort also encompassed 714,970 population-based matched parental control participants and 12,497 parental siblings. Cox proportional hazard regression models were employed to investigate the associations between having a child with type 1 diabetes and incident MCE and all-cause death, and, as secondary outcomes, acute coronary syndrome and ischaemic heart disease (IHD). We adjusted for potential confounders including parental type 1 diabetes and country of birth.\n\nDuring follow-up (median 12 years, range 0-35), we detected no associations between parenting a child with type 1 diabetes and MCE in mothers (adjusted HR [aHR] 1.02; 95% CI 0.90, 1.15) or in fathers (aHR 1.01; 95% CI 0.94, 1.08). We noted an increased hazard of IHD in exposed mothers (aHR 1.21; 95% CI 1.05, 1.41) with no corresponding signal in fathers (aHR 0.97; 95% CI 0.89, 1.05). Parental sibling analysis did not confirm the association in exposed mothers (aHR 1.01; 95% CI 0.73, 1.41). We further observed a slightly increased hazard of all-cause death in exposed fathers (aHR 1.09; 95% CI 1.01, 1.18), with a similar but non-significant estimate noted in exposed mothers (aHR 1.07; 95% CI 0.96, 1.20). The estimates from the sibling analyses of all-cause death in fathers and mothers were 1.12 (95% CI 0.90, 1.38) and 0.73 (95% CI 0.55, 0.96), respectively.\n\nHaving a child diagnosed with type 1 diabetes in Sweden was not associated with MCE, but possibly with all-cause mortality. Further studies are needed to disentangle potential underlying mechanisms, and to investigate parental health outcomes across the full lifespan.", "doi": "10.1007/s00125-024-06200-w", "pmid": "38922417", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC11410917"}, {"db": "pii", "key": "10.1007/s00125-024-06200-w"}], "notes": [], "created": "2026-08-20T06:38:57.222Z", "modified": "2026-08-20T06:38:57.511Z"}, {"entity": "publication", "iuid": "b9931f1b0bf341e088ae49a9ad9507b5", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/b9931f1b0bf341e088ae49a9ad9507b5.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/b9931f1b0bf341e088ae49a9ad9507b5"}}, "title": "The shared risk of diabetes between dog and cat owners and their pets: register based cohort study.", "authors": [{"family": "Delicano", "given": "Rachel Ann", "initials": "RA", "orcid": "0000-0001-9236-2591", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/54cf229b95ba4047a6a5d9072030dde4.json"}}, {"family": "Hammar", "given": "Ulf", "initials": "U", "orcid": "0000-0001-8367-5000", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b833fa7c77f542aabd5b04f4d9c02afd.json"}}, {"family": "Egenvall", "given": "Agneta", "initials": "A", "orcid": "0000-0002-8677-6066", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/6be77d87c213470bb2d34865673f7739.json"}}, {"family": "Westgarth", "given": "Carri", "initials": "C", "orcid": "0000-0003-0471-2761", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/667677f3c64d4be091bbafec59121673.json"}}, {"family": "Mubanga", "given": "Mwenya", "initials": "M", "orcid": "0000-0002-6877-4307", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/e59db54157224a199f5868e75a525bd6.json"}}, {"family": "Byberg", "given": "Liisa", "initials": "L", "orcid": "0000-0002-4421-6466", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/079e2e50ce7a4bc8ae14ecf7512a415d.json"}}, {"family": "Fall", "given": "Tove", "initials": "T", "orcid": "0000-0003-2071-5866", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/7dbbd468e6da4727b69333ade942c071.json"}}, {"family": "Kennedy", "given": "Beatrice", "initials": "B", "orcid": "0000-0002-0066-4814", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/cb88fcd6bead49978b129dffe779d8a0.json"}}], "type": "journal article", "published": "2020-12-10", "journal": {"title": "BMJ", "issn": "1756-1833", "volume": "371", "pages": "m4337", "issn-l": "1756-1833"}, "abstract": "To investigate whether dog and cat owners and their pets share a risk of developing diabetes.\n\nCohort study.\n\nRegister based longitudinal study, Sweden.\n\n208 980 owner-dog pairs and 123 566 owner-cat pairs identified during a baseline assessment period (1 January 2004 to 31 December 2006).\n\nType 2 diabetes events in dog and cat owners and diabetes events in their pets, including date of diagnosis during the follow-up period (1 January 2007 to 31 December 2012). Owners with type 2 diabetes were identified by combining information from the National Patient Register, the Cause of Death Register, and the Swedish Prescribed Drug Register. Information on diabetes in the pets was extracted from veterinary care insurance data. Multi-state models were used to assess the hazard ratios with 95% confidence intervals and to adjust for possible shared risk factors, including personal and socioeconomic circumstances.\n\nThe incidence of type 2 diabetes during follow-up was 7.7 cases per 1000 person years at risk in dog owners and 7.9 cases per 1000 person years at risk in cat owners. The incidence of diabetes in the pets was 1.3 cases per 1000 dog years at risk and 2.2 cases per 1000 cat years at risk. The crude hazard ratio for type 2 diabetes in owners of a dog with diabetes compared with owners of a dog without diabetes was 1.38 (95% confidence interval 1.10 to 1.74), with a multivariable adjusted hazard ratio of 1.32 (1.04 to 1.68). Having an owner with type 2 diabetes was associated with an increased hazard of diabetes in the dog (crude hazard ratio 1.28, 1.01 to 1.63), which was attenuated after adjusting for owner's age, with the confidence interval crossing the null (1.11, 0.87 to 1.42). No association was found between type 2 diabetes in cat owners and diabetes in their cats (crude hazard ratio 0.99, 0.74 to 1.34, and 1.00, 0.78 to 1.28, respectively).\n\nData indicated that owners of a dog with diabetes were more likely to develop type 2 diabetes during follow-up than owners of a dog without diabetes. It is possible that dogs with diabetes could serve as a sentinel for shared diabetogenic health behaviours and environmental exposures.", "doi": "10.1136/bmj.m4337", "pmid": "33303475", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC7726310"}], "notes": [], "created": "2026-08-20T12:02:03.884Z", "modified": "2026-08-20T12:02:04.017Z"}]}