{"entity": "publication", "iuid": "e046ce77f11c4957a24f695d3f7dbe86", "timestamp": "2026-08-25T21:25:41.009Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/e046ce77f11c4957a24f695d3f7dbe86.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/e046ce77f11c4957a24f695d3f7dbe86"}}, "title": "Vaginal microbiota and human papillomavirus infection among young Swedish women.", "authors": [{"family": "Cheng", "given": "Liqin", "initials": "L"}, {"family": "Norenhag", "given": "Johanna", "initials": "J"}, {"family": "Hu", "given": "Yue O O", "initials": "YOO", "orcid": "0000-0002-2025-2198", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/54d7339204704cb2b511f8ac6c8f0395.json"}}, {"family": "Brusselaers", "given": "Nele", "initials": "N"}, {"family": "Fransson", "given": "Emma", "initials": "E", "orcid": "0000-0001-9010-8522", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/8c05290187ec426b8804eefc3d954971.json"}}, {"family": "\u00c4hrlund-Richter", "given": "Andreas", "initials": "A"}, {"family": "Gu\u00f0nad\u00f3ttir", "given": "Unnur", "initials": "U"}, {"family": "Angelidou", "given": "Pia", "initials": "P"}, {"family": "Zha", "given": "Yinghua", "initials": "Y"}, {"family": "Hamsten", "given": "Marica", "initials": "M"}, {"family": "Schuppe-Koistinen", "given": "Ina", "initials": "I"}, {"family": "Olovsson", "given": "Matts", "initials": "M"}, {"family": "Engstrand", "given": "Lars", "initials": "L"}, {"family": "Du", "given": "Juan", "initials": "J", "orcid": "0000-0001-7649-9571", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f67834a614ca4cd4aff026e5e9a1a1e4.json"}}], "type": "comparative study", "published": "2020-10-12", "journal": {"title": "NPJ Biofilms Microbiomes", "issn": "2055-5008", "volume": "6", "issue": "1", "pages": "39", "issn-l": null}, "abstract": "Human papillomavirus (HPV) infection is one of the most common sexually transmitted diseases. To define the HPV-associated microbial community among a high vaccination coverage population, we carried out a cross-sectional study with 345 young Swedish women. The microbial composition and its association with HPV infection, including 27 HPV types, were analyzed. Microbial alpha-diversity was found significantly higher in the HPV-infected group (especially with oncogenic HPV types and multiple HPV types), compared with the HPV negative group. The vaginal microbiota among HPV-infected women was characterized by a larger number of bacterial vaginosis-associated bacteria (BVAB), Sneathia, Prevotella, and Megasphaera. In addition, the correlation analysis demonstrated that twice as many women with non-Lactobacillus-dominant vaginal microbiota were infected with oncogenic HPV types, compared with L. crispatus-dominated vaginal microbiota. The data suggest that HPV infection, especially oncogenic HPV types, is strongly associated with a non-Lactobacillus-dominant vaginal microbiota, regardless of age and vaccination status.", "doi": "10.1038/s41522-020-00146-8", "pmid": "33046723", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC7552401"}, {"db": "pii", "key": "10.1038/s41522-020-00146-8"}], "notes": [], "created": "2026-08-21T11:50:20.799Z", "modified": "2026-08-21T11:50:20.867Z"}