{"entity": "publication", "iuid": "d9ec338bfde54ed990213cf582e4b0ad", "timestamp": "2026-09-03T05:16:10.863Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/d9ec338bfde54ed990213cf582e4b0ad.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/d9ec338bfde54ed990213cf582e4b0ad"}}, "title": "RNAcentral 2021: secondary structure integration, improved sequence search and new member databases.", "authors": [{"family": "RNAcentral Consortium", "given": "", "initials": ""}], "type": "journal article", "published": "2021-01-08", "journal": {"title": "Nucleic Acids Res.", "issn": "1362-4962", "volume": "49", "issue": "D1", "pages": "D212-D220", "issn-l": "0305-1048"}, "abstract": "RNAcentral is a comprehensive database of non-coding RNA (ncRNA) sequences that provides a single access point to 44 RNA resources and >18 million ncRNA sequences from a wide range of organisms and RNA types. RNAcentral now also includes secondary (2D) structure information for >13 million sequences, making RNAcentral the world's largest RNA 2D structure database. The 2D diagrams are displayed using R2DT, a new 2D structure visualization method that uses consistent, reproducible and recognizable layouts for related RNAs. The sequence similarity search has been updated with a faster interface featuring facets for filtering search results by RNA type, organism, source database or any keyword. This sequence search tool is available as a reusable web component, and has been integrated into several RNAcentral member databases, including Rfam, miRBase and snoDB. To allow for a more fine-grained assignment of RNA types and subtypes, all RNAcentral sequences have been annotated with Sequence Ontology terms. The RNAcentral database continues to grow and provide a central data resource for the RNA community. RNAcentral is freely available at https://rnacentral.org.", "doi": "10.1093/nar/gkaa921", "pmid": "33106848", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC7779037"}, {"db": "pii", "key": "5940500"}], "notes": [], "created": "2026-08-21T12:11:09.695Z", "modified": "2026-08-21T12:11:09.721Z"}