{"entity": "publication", "iuid": "bb2ddebddd614a58a6501786af9b222b", "timestamp": "2026-08-20T20:36:38.499Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/bb2ddebddd614a58a6501786af9b222b.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/bb2ddebddd614a58a6501786af9b222b"}}, "title": "Sulfilimines: An Underexplored Bioisostere for Drug Design?", "authors": [{"family": "Arvidsson", "given": "Per I", "initials": "PI", "orcid": "0000-0002-9453-6812", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/84789ce64d004c83919336cdf43c903e.json"}}], "type": "journal article", "published": "2025-02-27", "journal": {"title": "J Med Chem", "issn": "1520-4804", "volume": "68", "issue": "4", "pages": "4056-4058", "issn-l": "0022-2623"}, "abstract": "Sulfilimines have so far received little attention as a bioisostere for sulfoxides in the design of biologically active compounds. A recent study on physicochemical and in vitro drug-like properties shows that sulfilimines deserve a place in the medicinal chemist's toolbox.", "doi": "10.1021/acs.jmedchem.5c00195", "pmid": "39887148", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC11874043"}], "notes": [], "created": "2026-08-20T08:10:52.352Z", "modified": "2026-08-20T08:10:52.425Z"}