{"entity": "publication", "iuid": "8c4c237517a64bc6bc0a34d650a64186", "timestamp": "2026-08-20T20:57:59.809Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/8c4c237517a64bc6bc0a34d650a64186.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/8c4c237517a64bc6bc0a34d650a64186"}}, "title": "The Oxidation of Electron-Rich Arenes Using a H2O2-Proline System.", "authors": [{"family": "Chetty", "given": "Lloyd C", "initials": "LC"}, {"family": "Kruger", "given": "Hendrik G", "initials": "HG", "orcid": "0000-0003-0606-2053", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/88f669867879452ca86ab92c27fd285c.json"}}, {"family": "Arvidsson", "given": "Per I", "initials": "PI"}, {"family": "Maguire", "given": "Glenn E M", "initials": "GEM"}, {"family": "Govender", "given": "Thavendran", "initials": "T", "orcid": "0000-0003-2511-2503", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/77ef43839d9e476f95d124c9c34b81fa.json"}}, {"family": "Naicker", "given": "Tricia", "initials": "T", "orcid": "0000-0002-7134-6258", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/f5b1b1625e8c43859647736baa3e83d9.json"}}], "type": "journal article", "published": "2024-09-03", "journal": {"title": "ACS Omega", "issn": "2470-1343", "volume": "9", "issue": "35", "pages": "37155-37162", "issn-l": "2470-1343"}, "abstract": "This study introduces a novel proline-catalyzed oxidation system employing hydrogen peroxide to synthesize quinones from a diverse range of substrates, including hydroquinones, phenols, resorcinols, aldehydes, and polycyclic aromatics. This approach is well-aligned with green chemistry principles, offering a more environmentally benign approach than earlier studies. Notably, this approach uses cost-effective reagents, proline as a readily available organocatalyst, reduced equivalents of H2O2, metal-free conditions, and notably short reaction times to achieve moderate-to-high yields. This promising approach encourages further exploration of the H2O2-proline system in oxidation reactions. This study's innovative approach and good results set a strong foundation for future research to expand the scope and efficiency of green oxidation processes.", "doi": "10.1021/acsomega.4c04383", "pmid": "39246484", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC11375719"}], "notes": [], "created": "2026-08-20T08:12:36.924Z", "modified": "2026-08-20T08:12:37.006Z"}