{"entity": "publication", "iuid": "7bd6902aa9b240f7b473b13daf1b3840", "timestamp": "2026-09-30T01:54:42.243Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/7bd6902aa9b240f7b473b13daf1b3840.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/7bd6902aa9b240f7b473b13daf1b3840"}}, "title": "Targeting SOX9 for degradation to inhibit chemoresistance, metastatic spread, and recurrence.", "authors": [{"family": "Suryo Rahmanto", "given": "Aldwin", "initials": "A", "orcid": "0000-0002-4593-286X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/59328511ffe441f08443f83089cc909b.json"}}, {"family": "Swartling", "given": "Fredrik J", "initials": "FJ", "orcid": "0000-0002-8460-4367", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/2e673fa8c86348fb8c1a2ae34ba7ba9a.json"}}, {"family": "Sangfelt", "given": "Olle", "initials": "O", "orcid": "0000-0002-0316-0195", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/2bc4930422a046f69295e2c59a569657.json"}}], "type": "journal article", "published": "2016-11-08", "journal": {"title": "Mol Cell Oncol", "issn": "2372-3556", "volume": "4", "issue": "1", "pages": "e1252871", "issn-l": null}, "abstract": "Cancer cells with stem-like properties are believed to contribute to treatment resistance, dissemination, and recurrence. SOX9 controls stem cell plasticity and its deregulation may provide a basis for tumor progression. Here, we summarize our findings of targeted SOX9 destruction by SCFFBW7 (Skp1/Cul1/F-box) in medulloblastoma and its potential for therapeutic intervention.", "doi": "10.1080/23723556.2016.1252871", "pmid": "28197531", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC5286959"}, {"db": "pii", "key": "1252871"}], "notes": [], "created": "2026-09-23T12:40:14.830Z", "modified": "2026-09-23T12:40:14.961Z"}