{"entity": "publication", "iuid": "6908e27ec00d43e7a1da9096b6a92f30", "timestamp": "2026-10-02T02:24:32.808Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/6908e27ec00d43e7a1da9096b6a92f30.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/6908e27ec00d43e7a1da9096b6a92f30"}}, "title": "Enhancing a De Novo Enzyme Activity by Computationally-Focused, Ultra-Low-Throughput Sequence Screening", "authors": [{"family": "Risso", "given": "Valeria A", "initials": "VA"}, {"family": "Romero-Rivera", "given": "Adrian", "initials": "A"}, {"family": "Gutierrez-Rus", "given": "Luis I", "initials": "LI", "orcid": "0000-0001-5521-1989", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b88da9efb8524264b141a7106ef9e324.json"}}, {"family": "Ortega-Mun\u0303oz", "given": "Mariano", "initials": "M"}, {"family": "Santoyo-Gonzalez", "given": "Francisco", "initials": "F", "orcid": "0000-0002-2142-3067", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/6ba3a5d57e2b4ec0a5446c53cd5bbd62.json"}}, {"family": "Gavira", "given": "Jose\u0301 A", "initials": "JA", "orcid": "0000-0002-7386-6484", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/80d442e3aee648dcb0bf039f150a86fe.json"}}, {"family": "Sanchez Ruiz", "given": "Jose Manuel", "initials": "JM", "orcid": "0000-0002-9056-3928", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ec6a0d0b7da24d9885cc89f4504033c8.json"}}, {"family": "Kamerlin", "given": "Shina Caroline Lynn", "initials": "SCL", "orcid": "0000-0002-3190-1173", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c4540c85432f4cdf952b0ef7cfe1d875.json"}}], "type": "posted-content", "published": "2020-04-06", "journal": {"issn-l": null}, "abstract": null, "doi": "10.26434/chemrxiv.11749854.v2", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-09-23T15:11:06.520Z", "modified": "2026-09-24T07:34:23.591Z"}