{"entity": "publication", "iuid": "4275e647bd244599a5d5fd305a5032e7", "timestamp": "2026-08-26T20:41:33.259Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/4275e647bd244599a5d5fd305a5032e7.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/4275e647bd244599a5d5fd305a5032e7"}}, "title": "Clinical and functional impact of recurrent S1PR1 mutations in mantle cell lymphoma.", "authors": [{"family": "Wasik", "given": "Agata M", "initials": "AM"}, {"family": "Wu", "given": "Chenglin", "initials": "C"}, {"family": "Mansouri", "given": "Larry", "initials": "L"}, {"family": "Rosenquist", "given": "Richard", "initials": "R"}, {"family": "Pan-Hammarstr\u00f6m", "given": "Qiang", "initials": "Q"}, {"family": "Sander", "given": "Birgitta", "initials": "B"}], "type": "journal article", "published": "2018-03-27", "journal": {"title": "Blood Adv", "issn": "2473-9529", "volume": "2", "issue": "6", "pages": "621-625", "issn-l": null}, "abstract": "S1PR1 mutations are present in 7.8% of patients with MCL and are significantly more frequent at relapse. S1PR1 mutations reduce expression of the S1PR1 receptor, which mediates migration towards the tissue-to-blood egress factor S1P in MCL. .", "doi": "10.1182/bloodadvances.2017014860", "pmid": "29549086", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC5873236"}, {"db": "pii", "key": "bloodadvances.2017014860"}], "notes": [], "created": "2026-08-21T12:33:13.603Z", "modified": "2026-08-21T12:33:13.646Z"}