{"entity": "publication", "iuid": "2da6730001974cd09d04561a582e08f0", "timestamp": "2026-08-20T20:48:40.181Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/2da6730001974cd09d04561a582e08f0.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/2da6730001974cd09d04561a582e08f0"}}, "title": "News from the T cell trogocytosis front.", "authors": [{"family": "Barbera", "given": "Stefano", "initials": "S"}, {"family": "Dimberg", "given": "Anna", "initials": "A"}, {"family": "Essand", "given": "Magnus", "initials": "M"}], "type": "journal article", "published": "2025-10-00", "journal": {"title": "Trends Immunol.", "issn": "1471-4981", "volume": "46", "issue": "10", "pages": "677-689", "issn-l": "1471-4906"}, "abstract": "T cells can exchange parts of their plasma membrane along with membrane-associated proteins through trogocytosis. During trogocytosis only certain subsets of membrane-associated proteins seem to be exchanged suggesting a fine-tuned mechanism regulating the selection of what can be transferred. In this review, we describe potential models of trogocytosis and discuss mechanisms that could regulate this process in T cells. Additionally, we delve into how exchanged proteins polarize on the surface of recipient cells, discuss how trogocytosis allows T cells to acquire new functions, and summarize ways to modulate this process in T cells. Understanding trogocytosis can help us better understand the immune response and develop more effective immunotherapies.", "doi": "10.1016/j.it.2025.07.008", "pmid": "40816969", "labels": [], "xrefs": [{"db": "pii", "key": "S1471-4906(25)00175-9"}], "notes": [], "created": "2026-08-20T07:58:10.262Z", "modified": "2026-08-20T07:58:10.312Z"}