{"entity": "journal", "iuid": "381fa5f9bf8c4f79a5115e3b02c1e40c", "timestamp": "2026-09-26T23:02:18.139Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/journal/Resusc%20Plus.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/journal/Resusc%20Plus"}}, "title": "Resusc Plus", "issn": "2666-5204", "issn-l": null, "publications_count": 1, "publications": [{"entity": "publication", "iuid": "c803ee5e574345a0b9ca9d86dc178201", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/c803ee5e574345a0b9ca9d86dc178201.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/c803ee5e574345a0b9ca9d86dc178201"}}, "title": "Exploring the impact of age on the predictive power of the National Early Warning score (NEWS) 2, and long-term prognosis among patients reviewed by a Rapid Response Team: A prospective, multi-centre study.", "authors": [{"family": "Thor\u00e9n", "given": "Anna", "initials": "A"}, {"family": "Franko", "given": "Mikael Andersson", "initials": "MA"}, {"family": "Joelsson-Alm", "given": "Eva", "initials": "E"}, {"family": "Rawshani", "given": "Araz", "initials": "A"}, {"family": "Kahan", "given": "Thomas", "initials": "T"}, {"family": "Engdahl", "given": "Johan", "initials": "J"}, {"family": "Jonsson", "given": "Martin", "initials": "M"}, {"family": "Dj\u00e4rv", "given": "Therese", "initials": "T"}, {"family": "Sp\u00e5ngfors", "given": "Martin", "initials": "M"}], "type": "journal article", "published": "2025-01-00", "journal": {"title": "Resusc Plus", "issn": "2666-5204", "volume": "21", "pages": "100839", "issn-l": null}, "abstract": "To explore the impact of age on the discriminative ability of the National Early Warning Score (NEWS) 2 in prediction of unanticipated Intensive Care Unit (ICU) admission, in-hospital cardiac arrest (IHCA) and mortality within 24 hours of Rapid Response Team (RRT) review. Furthermore, to investigate 30- and 90-day mortality, and the discriminative ability of NEWS 2 in prediction of long-term mortality among RRT-reviewed patients.\n\nProspective, multi-centre study based on 830 complete cases. Data was collected by RRTs in 24 hospitals between October 2019, and January 2020. All NEWS 2 scores were uniformly calculated by the study team. Age was analysed as a continuous variable, in a spline regression model, and categorized into five different models, subsequently explored as additive variables to NEWS 2. The discriminative ability of NEWS 2 was evaluated using the Area under the receiver operating characteristics (AUROC).\n\nThe discriminative ability of NEWS 2 alone in predicting 30-day mortality was weak. Adding age as a covariate improved the predictive performance (AUROC 0.66, 0.62-0.70 to 0.70, 0.65-0.73, p = 0.01, 95 % Confidence Interval). There were differences across age groups, with the best discriminative ability identified among patients aged 45-54 years. The 30- and 90-day mortality was 31% and 33% respectively.\n\nAdding age as a covariate improved the discriminative ability of NEWS 2 in the prediction of 30-day mortality among RRT-reviewed patients, with variations observed across age categories. The long- term prognosis of RRT-reviewed patients was poor.", "doi": "10.1016/j.resplu.2024.100839", "pmid": "39811470", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC11732060"}, {"db": "pii", "key": "S2666-5204(24)00290-X"}], "notes": [], "created": "2026-09-23T15:43:08.274Z", "modified": "2026-09-23T15:43:08.318Z"}], "created": "2026-09-23T15:43:08.281Z", "modified": "2026-09-23T15:43:08.281Z"}