{"entity": "journal", "iuid": "a0ca1f19bd45489cb6ee99f5bda97dd7", "timestamp": "2026-08-15T12:35:18.550Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/journal/Proceedings%20of%20the%20Royal%20Society%20B%3A%20Biological%20Sciences.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/journal/Proceedings%20of%20the%20Royal%20Society%20B%3A%20Biological%20Sciences"}}, "title": "Proceedings of the Royal Society B: Biological Sciences", "issn": "0962-8452", "issn-l": "0962-8452", "publications_count": 3, "publications": [{"entity": "publication", "iuid": "94e95b57eaea4a67957a857920c7c9df", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/94e95b57eaea4a67957a857920c7c9df.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/94e95b57eaea4a67957a857920c7c9df"}}, "title": "Evolutionary consequences of self-fertilization in plants", "authors": [{"family": "Wright", "given": "S I", "initials": "SI"}, {"family": "Kalisz", "given": "S", "initials": "S"}, {"family": "Slotte", "given": "T", "initials": "T"}], "type": "journal-article", "published": "2013-04-17", "journal": {"volume": "280", "issn": "0962-8452", "issue": "1760", "pages": "20130133-20130133", "title": "Proceedings of the Royal Society B: Biological Sciences", "issn-l": "0962-8452"}, "abstract": "The transition from outcrossing to self-fertilization is one of the most common evolutionary changes in plants, yet only about 10-15% of flowering plants are predominantly selfing. To explain this phenomenon, Stebbins proposed that selfing may be an 'evolutionary dead end'. According to this hypothesis, transitions from outcrossing to selfing are irreversible, and selfing lineages suffer from an increased risk of extinction owing to a reduced potential for adaptation. Thus, although selfing can be advantageous in the short term, selfing lineages may be mostly short-lived owing to higher extinction rates. Here, we review recent results relevant to the 'dead-end hypothesis' of selfing and the maintenance of outcrossing over longer evolutionary time periods. In particular, we highlight recent results regarding diversification rates in self-incompatible and self-compatible taxa, and review evidence regarding the accumulation of deleterious mutations in selfing lineages. We conclude that while some aspects of the hypothesis of selfing as a dead end are supported by theory and empirical results, the evolutionary and ecological mechanisms remain unclear. We highlight the need for more studies on the effects of quantitative changes in outcrossing rates and on the potential for adaptation, particularly in selfing plants. In addition, there is growing evidence that transitions to selfing may themselves be drivers of speciation, and future studies of diversification and speciation should investigate this further.", "doi": "10.1098/rspb.2013.0133", "pmid": "23595268", "labels": {"Affiliated researcher": null, "Tanja Slotte": null, "SciLifeLab Fellow": null}, "xrefs": [], "notes": [], "created": "2018-12-03T14:31:35.381Z", "modified": "2022-11-07T11:38:19.792Z"}, {"entity": "publication", "iuid": "459e5e312d9748849145c5717fafcc00", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/459e5e312d9748849145c5717fafcc00.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/459e5e312d9748849145c5717fafcc00"}}, "title": "The evolutionary history of haptophytes and cryptophytes: phylogenomic evidence for separate origins", "authors": [{"family": "Burki", "given": "F", "initials": "F"}, {"family": "Okamoto", "given": "N", "initials": "N"}, {"family": "Pombert", "given": "J F", "initials": "JF"}, {"family": "Keeling", "given": "P J", "initials": "PJ"}], "type": "journal-article", "published": "2012-06-07", "journal": {"volume": "279", "issn": "0962-8452", "issue": "1736", "pages": "2246-2254", "title": "Proceedings of the Royal Society B: Biological Sciences", "issn-l": "0962-8452"}, "abstract": "An important missing piece in the puzzle of how plastids spread across the eukaryotic tree of life is a robust evolutionary framework for the host lineages. Four assemblages are known to harbour plastids derived from red algae and, according to the controversial chromalveolate hypothesis, these all share a common ancestry. Phylogenomic analyses have consistently shown that stramenopiles and alveolates are closely related, but haptophytes and cryptophytes remain contentious; they have been proposed to branch together with several heterotrophic groups in the newly erected Hacrobia. Here, we tested this question by producing a large expressed sequence tag dataset for the katablepharid Roombia truncata, one of the last hacrobian lineages for which genome-level data are unavailable, and combined this dataset with the recently completed genome of the cryptophyte Guillardia theta to build an alignment composed of 258 genes. Our analyses strongly support haptophytes as sister to the SAR group, possibly together with telonemids and centrohelids. We also confirmed the common origin of katablepharids and cryptophytes, but these lineages were not related to other hacrobians; instead, they branch with plants. Our study resolves the evolutionary position of haptophytes, an ecologically critical component of the oceans, and proposes a new hypothesis for the origin of cryptophytes.", "doi": "10.1098/rspb.2011.2301", "pmid": "22298847", "labels": {"Fabien Burki": null, "SciLifeLab Fellow": null}, "xrefs": [], "notes": [], "created": "2018-12-03T14:28:30.800Z", "modified": "2022-11-07T11:31:56.779Z"}, {"entity": "publication", "iuid": "32ff728bbf6c40519e13ae62ff823184", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/32ff728bbf6c40519e13ae62ff823184.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/32ff728bbf6c40519e13ae62ff823184"}}, "title": "Evolutionary position of breviate amoebae and the primary eukaryote divergence.", "authors": [{"family": "Minge", "given": "Marianne A", "initials": "MA"}, {"family": "Silberman", "given": "Jeffrey D", "initials": "JD"}, {"family": "Orr", "given": "Russell J S", "initials": "RJ"}, {"family": "Cavalier-Smith", "given": "Thomas", "initials": "T"}, {"family": "Shalchian-Tabrizi", "given": "Kamran", "initials": "K"}, {"family": "Burki", "given": "Fabien", "initials": "F"}, {"family": "Skjaeveland", "given": "Asmund", "initials": "A"}, {"family": "Jakobsen", "given": "Kjetill S", "initials": "KS"}], "type": "journal article", "published": "2009-02-22", "journal": {"title": "Proceedings of the Royal Society B: Biological Sciences", "issn": "0962-8452", "volume": "276", "issue": "1657", "pages": "597-604", "issn-l": "0962-8452"}, "abstract": "Integration of ultrastructural and molecular sequence data has revealed six supergroups of eukaryote organisms (excavates, Rhizaria, chromalveolates, Plantae, Amoebozoa and opisthokonts), and the root of the eukaryote evolutionary tree is suggested to lie between unikonts (Amoebozoa, opisthokonts) and bikonts (the other supergroups). However, some smaller lineages remain of uncertain affinity. One of these unassigned taxa is the anaerobic, free-living, amoeboid flagellate Breviata anathema, which is of key significance as it is unclear whether it is a unikont (i.e. possibly the deepest branching amoebozoan) or a bikont. To establish its evolutionary position, we sequenced thousands of Breviata genes and calculated trees using 78 protein sequences. Our trees and specific substitutions in the 18S RNA sequence indicate that Breviata is related to other Amoebozoa, thereby significantly increasing the cellular diversity of this phylum and establishing Breviata as a deep-branching unikont. We discuss the implications of these results for the ancestral state of Amoebozoa and eukaryotes generally, demonstrating that phylogenomics of phylogenetically 'nomadic' species can elucidate key questions in eukaryote evolution. Furthermore, mitochondrial genes among the Breviata ESTs demonstrate that Breviata probably contains a modified anaerobic mitochondrion. With these findings, remnants of mitochondria have been detected in all putatively deep-branching amitochondriate organisms.", "doi": "10.1098/rspb.2008.1358", "pmid": "19004754", "labels": {"Fabien Burki": null, "SciLifeLab Fellow": null}, "xrefs": [{"db": "pii", "key": "276/1657/597"}, {"db": "pmc", "key": "PMC2660946"}], "notes": [], "created": "2020-09-28T12:16:16.819Z", "modified": "2022-11-07T11:31:56.910Z"}], "created": "2018-12-03T14:28:30.813Z", "modified": "2020-11-27T13:12:51.947Z"}