{"entity": "journal", "iuid": "5f37472509d647b182cc209c6b4169e1", "timestamp": "2026-05-12T21:29:17.441Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/journal/Langmuir.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/journal/Langmuir"}}, "title": "Langmuir", "issn": "1520-5827", "issn-l": "0743-7463", "publications_count": 10, "publications": [{"entity": "publication", "iuid": "7cc9ceb62973482195d1ed302e5c3ff6", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/7cc9ceb62973482195d1ed302e5c3ff6.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/7cc9ceb62973482195d1ed302e5c3ff6"}}, "title": "Peptide-Induced Lipid Flip-Flop in Asymmetric Liposomes Measured by Small Angle Neutron Scattering.", "authors": [{"family": "Nguyen", "given": "Michael H L", "initials": "MHL"}, {"family": "DiPasquale", "given": "Mitchell", "initials": "M"}, {"family": "Rickeard", "given": "Brett W", "initials": "BW"}, {"family": "Doktorova", "given": "Milka", "initials": "M"}, {"family": "Heberle", "given": "Frederick A", "initials": "FA", "orcid": "0000-0002-0424-3240", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/2557f5621a0b4c87b5f4702fbc7b6bdb.json"}}, {"family": "Scott", "given": "Haden L", "initials": "HL"}, {"family": "Barrera", "given": "Francisco N", "initials": "FN"}, {"family": "Taylor", "given": "Graham", "initials": "G"}, {"family": "Collier", "given": "Charles P", "initials": "CP", "orcid": "0000-0002-8198-793X", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/c9ebfa8b6f4d4fafaccc956166f0a187.json"}}, {"family": "Stanley", "given": "Christopher B", "initials": "CB", "orcid": "0000-0002-4226-7710", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/5d6a186b9b434487907f1035cb1c8edf.json"}}, {"family": "Katsaras", "given": "John", "initials": "J"}, {"family": "Marquardt", "given": "Drew", "initials": "D", "orcid": "0000-0001-6848-2497", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/114cdc1c929d46308422b3b587f8e1d6.json"}}], "type": "journal article", "published": "2019-09-10", "journal": {"title": "Langmuir", "issn": "1520-5827", "issn-l": "0743-7463", "volume": "35", "issue": "36", "pages": "11735-11744"}, "abstract": "Despite the prevalence of lipid transbilayer asymmetry in natural plasma membranes, most biomimetic model membranes studied are symmetric. Recent advances have helped to overcome the difficulties in preparing asymmetric liposomes in vitro, allowing for the examination of a larger set of relevant biophysical questions. Here, we investigate the stability of asymmetric bilayers by measuring lipid flip-flop with time-resolved small-angle neutron scattering (SANS). Asymmetric large unilamellar vesicles with inner bilayer leaflets containing predominantly 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and outer leaflets composed mainly of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) displayed slow spontaneous flip-flop at 37 \u25e6C (half-time, t1/2 = 140 h). However, inclusion of peptides, namely, gramicidin, alamethicin, melittin, or pHLIP (i.e., pH-low insertion peptide), accelerated lipid flip-flop. For three of these peptides (i.e., pHLIP, alamethicin, and melittin), each of which was added externally to preformed asymmetric vesicles, we observed a completely scrambled bilayer in less than 2 h. Gramicidin, on the other hand, was preincorporated during the formation of the asymmetric liposomes and showed a time resolvable 8-fold increase in the rate of lipid asymmetry loss. These results point to a membrane surface-related (e.g., adsorption/insertion) event as the primary driver of lipid scrambling in the asymmetric model membranes of this study. We discuss the implications of membrane peptide binding, conformation, and insertion on lipid asymmetry.", "doi": "10.1021/acs.langmuir.9b01625", "pmid": "31408345", "labels": {"Milka Doktorova": null, "DDLS Fellow": null}, "xrefs": [{"db": "mid", "key": "NIHMS1612790"}, {"db": "pmc", "key": "PMC7393738"}], "notes": [], "created": "2024-11-27T12:18:10.589Z", "modified": "2024-11-29T12:16:50.099Z"}, {"entity": "publication", "iuid": "3b13f902837242f88b379e7427035525", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/3b13f902837242f88b379e7427035525.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/3b13f902837242f88b379e7427035525"}}, "title": "Emulsions Stabilized by Chitosan-Modified Silica Nanoparticles: pH Control of Structure-Property Relations.", "authors": [{"family": "Alison", "given": "Lauriane", "initials": "L"}, {"family": "Demir\u00f6rs", "given": "Ahmet F", "initials": "AF"}, {"family": "Tervoort", "given": "Elena", "initials": "E"}, {"family": "Teleki", "given": "Alexandra", "initials": "A"}, {"family": "Vermant", "given": "Jan", "initials": "J"}, {"family": "Studart", "given": "Andre R", "initials": "AR"}], "type": "journal article", "published": "2018-05-29", "journal": {"title": "Langmuir", "issn": "1520-5827", "volume": "34", "issue": "21", "pages": "6147-6160", "issn-l": "0743-7463"}, "abstract": "In food-grade emulsions, particles with an appropriate surface modification can be used to replace surfactants and potentially enhance the stability of emulsions. During the life cycle of products based on such emulsions, they can be exposed to a broad range of pH conditions and hence it is crucial to understand how pH changes affect stability of emulsions stabilized by particles. Here, we report on a comprehensive study of the stability, microstructure, and macroscopic behavior of pH-controlled oil-in-water emulsions containing silica nanoparticles modified with chitosan, a food-grade polycation. We found that the modified colloidal particles used as stabilizers behave differently depending on the pH, resulting in unique emulsion structures at multiple length scales. Our findings are rationalized in terms of the different emulsion stabilization mechanisms involved, which are determined by the pH-dependent charges and interactions between the colloidal building blocks of the system. At pH 4, the silica particles are partially hydrophobized through chitosan modification, favoring their adsorption at the oil-water interface and the formation of Pickering emulsions. At pH 5.5, the particles become attractive and the emulsion is stabilized by a network of agglomerated particles formed between the droplets. Finally, chitosan aggregates form at pH 9 and these act as the emulsion stabilizers under alkaline conditions. These insights have important implications for the processing and use of particle-stabilized emulsions. On one hand, changes in pH can lead to undesired macroscopic phase separation or coalescence of oil droplets. On the other hand, the pH effect on emulsion behavior can be harnessed in industrial processing, either to tune their flow response by altering the pH between processing stages or to produce pH-responsive emulsions that enhance the functionality of the emulsified end products.", "doi": "10.1021/acs.langmuir.8b00622", "pmid": "29719151", "labels": {"Alexandra Teleki": null, "SciLifeLab Fellow": null}, "xrefs": [], "notes": [], "created": "2020-11-30T21:40:04.569Z", "modified": "2022-11-07T11:29:43.300Z"}, {"entity": "publication", "iuid": "c8fd257266974aea946690de4f1d325c", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/c8fd257266974aea946690de4f1d325c.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/c8fd257266974aea946690de4f1d325c"}}, "title": "Pickering and Network Stabilization of Biocompatible Emulsions Using Chitosan-Modified Silica Nanoparticles.", "authors": [{"family": "Alison", "given": "Lauriane", "initials": "L"}, {"family": "R\u00fchs", "given": "Patrick A", "initials": "PA"}, {"family": "Tervoort", "given": "Elena", "initials": "E"}, {"family": "Teleki", "given": "Alexandra", "initials": "A"}, {"family": "Zanini", "given": "Michele", "initials": "M"}, {"family": "Isa", "given": "Lucio", "initials": "L"}, {"family": "Studart", "given": "Andr\u00e9 R", "initials": "AR"}], "type": "journal article", "published": "2016-12-20", "journal": {"title": "Langmuir", "issn": "1520-5827", "volume": "32", "issue": "50", "pages": "13446-13457", "issn-l": "0743-7463"}, "abstract": "Edible solid particles constitute an attractive alternative to surfactants as stabilizers of food-grade emulsions for products requiring a long-term shelf life. Here, we report on a new approach to stabilize edible emulsions using silica nanoparticles modified by noncovalently bound chitosan oligomers. Electrostatic modification with chitosan increases the hydrophobicity of the silica nanoparticles and favors their adsorption at the oil-water interface. The interfacial adsorption of the chitosan-modified silica particles enables the preparation of oil-in-water emulsions with small droplet sizes of a few micrometers through high-pressure homogenization. This approach enables the stabilization of food-grade emulsions for more than 3 months. The emulsion structure and stability can be effectively tuned by controlling the extent of chitosan adsorption on the silica particles. Bulk and interfacial rheology are used to highlight the two stabilization mechanisms involved. Low chitosan concentration (1 wt % with respect to silica) leads to the formation of a viscoelastic film of particles adsorbed at the oil-water interface, enabling Pickering stabilization of the emulsion. By contrast, a network of agglomerated particles formed around the droplets is the predominant stabilization mechanism of the emulsions at higher chitosan content (5 wt % with respect to silica). These two pathways against droplet coalescence and coarsening open up different possibilities to engineer the long-term stabilization of emulsions for food applications.", "doi": "10.1021/acs.langmuir.6b03439", "pmid": "27935304", "labels": {"Alexandra Teleki": null, "SciLifeLab Fellow": null}, "xrefs": [], "notes": [], "created": "2020-11-30T21:40:37.340Z", "modified": "2022-11-07T11:29:43.371Z"}, {"entity": "publication", "iuid": "0a16b76a8f7d45bbb8e1657992dd3a73", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/0a16b76a8f7d45bbb8e1657992dd3a73.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/0a16b76a8f7d45bbb8e1657992dd3a73"}}, "title": "Visualizing the Nonhomogeneous Structure of RAD51 Filaments Using Nanofluidic Channels.", "authors": [{"family": "Fornander", "given": "Louise H", "initials": "LH"}, {"family": "Frykholm", "given": "Karolin", "initials": "K"}, {"family": "Fritzsche", "given": "Joachim", "initials": "J"}, {"family": "Araya", "given": "Joshua", "initials": "J"}, {"family": "Nevin", "given": "Philip", "initials": "P"}, {"family": "Werner", "given": "Erik", "initials": "E"}, {"family": "\u00c7ak\u0131r", "given": "Ali", "initials": "A"}, {"family": "Persson", "given": "Fredrik", "initials": "F"}, {"family": "Garcin", "given": "Edwige B", "initials": "EB"}, {"family": "Beuning", "given": "Penny J", "initials": "PJ"}, {"family": "Mehlig", "given": "Bernhard", "initials": "B"}, {"family": "Modesti", "given": "Mauro", "initials": "M"}, {"family": "Westerlund", "given": "Fredrik", "initials": "F"}], "type": "journal article", "published": "2016-08-23", "journal": {"title": "Langmuir", "issn": "1520-5827", "volume": "32", "issue": "33", "pages": "8403-8412", "issn-l": "0743-7463"}, "abstract": "RAD51 is the key component of the homologous recombination pathway in eukaryotic cells and performs its task by forming filaments on DNA. In this study we investigate the physical properties of RAD51 filaments formed on DNA using nanofluidic channels and fluorescence microscopy. Contrary to the bacterial ortholog RecA, RAD51 forms inhomogeneous filaments on long DNA in vitro, consisting of several protein patches. We demonstrate that a permanent \"kink\" in the filament is formed where two patches meet if the stretch of naked DNA between the patches is short. The kinks are readily seen in the present microscopy approach but would be hard to identify using conventional single DNA molecule techniques where the DNA is more stretched. We also demonstrate that protein patches separated by longer stretches of bare DNA roll up on each other and this is visualized as transiently overlapping filaments. RAD51 filaments can be formed at several different conditions, varying the cation (Mg(2+) or Ca(2+)), the DNA substrate (single-stranded or double-stranded), and the RAD51 concentration during filament nucleation, and we compare the properties of the different filaments formed. The results provide important information regarding the physical properties of RAD51 filaments but also demonstrate that nanofluidic channels are perfectly suited to study protein-DNA complexes.", "doi": "10.1021/acs.langmuir.6b01877", "pmid": "27479732", "labels": {"Affiliated researcher": null}, "xrefs": [], "notes": [], "created": "2018-12-05T12:16:25.224Z", "modified": "2018-12-05T12:16:25.244Z"}, {"entity": "publication", "iuid": "6fb9e09a19d742f2ba5a885cde207515", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/6fb9e09a19d742f2ba5a885cde207515.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/6fb9e09a19d742f2ba5a885cde207515"}}, "title": "Subnanometer Structure of an Asymmetric Model Membrane: Interleaflet Coupling Influences Domain Properties.", "authors": [{"family": "Heberle", "given": "Frederick A", "initials": "FA"}, {"family": "Marquardt", "given": "Drew", "initials": "D"}, {"family": "Doktorova", "given": "Milka", "initials": "M"}, {"family": "Geier", "given": "Barbara", "initials": "B"}, {"family": "Standaert", "given": "Robert F", "initials": "RF"}, {"family": "Heftberger", "given": "Peter", "initials": "P"}, {"family": "Kollmitzer", "given": "Benjamin", "initials": "B"}, {"family": "Nickels", "given": "Jonathan D", "initials": "JD"}, {"family": "Dick", "given": "Robert A", "initials": "RA"}, {"family": "Feigenson", "given": "Gerald W", "initials": "GW"}, {"family": "Katsaras", "given": "John", "initials": "J"}, {"family": "London", "given": "Erwin", "initials": "E"}, {"family": "Pabst", "given": "Georg", "initials": "G"}], "type": "journal article", "published": "2016-05-24", "journal": {"title": "Langmuir", "issn": "1520-5827", "issn-l": "0743-7463", "volume": "32", "issue": "20", "pages": "5195-5200"}, "abstract": "Cell membranes possess a complex three-dimensional architecture, including nonrandom lipid lateral organization within the plane of a bilayer leaflet, and compositional asymmetry between the two leaflets. As a result, delineating the membrane structure-function relationship has been a highly challenging task. Even in simplified model systems, the interactions between bilayer leaflets are poorly understood, due in part to the difficulty of preparing asymmetric model membranes that are free from the effects of residual organic solvent or osmotic stress. To address these problems, we have modified a technique for preparing asymmetric large unilamellar vesicles (aLUVs) via cyclodextrin-mediated lipid exchange in order to produce tensionless, solvent-free aLUVs suitable for a range of biophysical studies. Leaflet composition and structure were characterized using isotopic labeling strategies, which allowed us to avoid the use of bulky labels. NMR and gas chromatography provided precise quantification of the extent of lipid exchange and bilayer asymmetry, while small-angle neutron scattering (SANS) was used to resolve bilayer structural features with subnanometer resolution. Isotopically asymmetric POPC vesicles were found to have the same bilayer thickness and area per lipid as symmetric POPC vesicles, demonstrating that the modified exchange protocol preserves native bilayer structure. Partial exchange of DPPC into the outer leaflet of POPC vesicles produced chemically asymmetric vesicles with a gel/fluid phase-separated outer leaflet and a uniform, POPC-rich inner leaflet. SANS was able to separately resolve the thicknesses and areas per lipid of coexisting domains, revealing reduced lipid packing density of the outer leaflet DPPC-rich phase compared to typical gel phases. Our finding that a disordered inner leaflet can partially fluidize ordered outer leaflet domains indicates some degree of interleaflet coupling, and invites speculation on a role for bilayer asymmetry in modulating membrane lateral organization.", "doi": "10.1021/acs.langmuir.5b04562", "pmid": "27128636", "labels": {"Milka Doktorova": null, "DDLS Fellow": null}, "xrefs": [{"db": "pmc", "key": "PMC4910133"}], "notes": [], "created": "2024-11-27T12:16:13.156Z", "modified": "2024-11-29T12:17:26.421Z"}, {"entity": "publication", "iuid": "4a561a57cea14fb7b1af3ee9296022ab", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/4a561a57cea14fb7b1af3ee9296022ab.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/4a561a57cea14fb7b1af3ee9296022ab"}}, "title": "Measuring lipid packing of model and cellular membranes with environment sensitive probes.", "authors": [{"family": "Sezgin", "given": "Erdinc", "initials": "E"}, {"family": "Sadowski", "given": "Tomasz", "initials": "T"}, {"family": "Simons", "given": "Kai", "initials": "K"}], "type": "journal article", "published": "2014-07-15", "journal": {"title": "Langmuir", "issn": "1520-5827", "volume": "30", "issue": "27", "pages": "8160-8166", "issn-l": "0743-7463"}, "abstract": "The extent of lipid packing is one of the key physicochemical features of biological membranes and is involved in many membrane processes. Polarity sensitive fluorescent probes are commonly used tools to measure membrane lipid packing in both artificial and biological membranes. In this paper, we have systematically compared eight different probes to measure membrane lipid ordering. We investigated how these probes behave in small unilamellar liposomes, phase-separated giant unilamellar vesicles, cell-derived giant plasma membrane vesicles, and live cells. We have tested the order sensitivity of a variety of measurable parameters, including generalized polarization, peak shift, or intensity shift. We also investigated internalization and photostability of the probes to assess probe potential for time-lapse live cell imaging. These results provide a catalogue of properties to facilitate the choice of probe according to need.", "doi": "10.1021/la501226v", "pmid": "24905799", "labels": {"Erdinc Sezgin": null, "SciLifeLab Fellow": null}, "xrefs": [], "notes": [], "created": "2020-09-28T09:15:25.964Z", "modified": "2022-11-07T11:31:19.470Z"}, {"entity": "publication", "iuid": "b3c131bc69b0424fa93c9a2d73d1c4b1", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/b3c131bc69b0424fa93c9a2d73d1c4b1.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/b3c131bc69b0424fa93c9a2d73d1c4b1"}}, "title": "Removal of total organic carbon from sewage wastewater using poly(ethylenimine)-functionalized magnetic nanoparticles.", "authors": [{"family": "Lakshmanan", "given": "Ramnath", "initials": "R"}, {"family": "Sanchez-Dominguez", "given": "Margarita", "initials": "M"}, {"family": "Matutes-Aquino", "given": "Jose A", "initials": "JA"}, {"family": "Wennmalm", "given": "Stefan", "initials": "S"}, {"family": "Kuttuva Rajarao", "given": "Gunaratna", "initials": "G"}], "type": "journal article", "published": "2014-02-04", "journal": {"title": "Langmuir", "issn": "1520-5827", "volume": "30", "issue": "4", "pages": "1036-1044", "issn-l": "0743-7463"}, "abstract": "The increased levels of organic carbon in sewage wastewater during recent years impose a great challenge to the existing wastewater treatment process (WWTP). Technological innovations are therefore sought that can reduce the release of organic carbon into lakes and seas. In the present study, magnetic nanoparticles (NPs) were synthesized, functionalized with poly(ethylenimine) (PEI), and characterized using TEM (transmission electron microscopy), X-ray diffraction (XRD), FTIR (Fourier transform infrared spectroscopy), CCS (confocal correlation spectroscopy), SICS (scattering interference correlation spectroscopy), magnetism studies, and thermogravimetric analysis (TGA). The removal of total organic carbon (TOC) and other contaminants using PEI-coated magnetic nanoparticles (PEI-NPs) was tested in wastewater obtained from the Hammarby Sj\u00f6stadsverk sewage plant, Sweden. The synthesized NPs were about 12 nm in diameter and showed a homogeneous particle size distribution in dispersion by TEM and CCS analyses, respectively. The magnetization curve reveals superparamagnetic behavior, and the NPs do not reach saturation because of surface anisotropy effects. A 50% reduction in TOC was obtained in 60 min when using 20 mg/L PEI-NPs in 0.5 L of wastewater. Along with TOC, other contaminants such as turbidity (89%), color (86%), total nitrogen (24%), and microbial content (90%) were also removed without significant changes in the mineral ion composition of wastewater. We conclude that the application of PEI-NPs has the potential to reduce the processing time, complexity, sludge production, and use of additional chemicals in the WWTP. ", "doi": "10.1021/la404076n", "pmid": "24428551", "labels": {"Affiliated researcher": null}, "xrefs": [], "notes": [], "created": "2018-12-05T09:59:53.187Z", "modified": "2018-12-05T09:59:53.221Z"}, {"entity": "publication", "iuid": "a811ffa81e324c87970995465ed551e4", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/a811ffa81e324c87970995465ed551e4.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/a811ffa81e324c87970995465ed551e4"}}, "title": "Continuous surface functionalization of flame-made TiO2 nanoparticles.", "authors": [{"family": "Teleki", "given": "Alexandra", "initials": "A"}, {"family": "Bjelobrk", "given": "Nada", "initials": "N"}, {"family": "Pratsinis", "given": "Sotiris E", "initials": "SE"}], "type": "journal article", "published": "2010-04-20", "journal": {"title": "Langmuir", "issn": "1520-5827", "volume": "26", "issue": "8", "pages": "5815-5822", "issn-l": "0743-7463"}, "abstract": "Hydrophilic TiO(2) particles made in a flame aerosol reactor were converted in situ to hydrophobic ones by silylation of their surface hydroxyl groups. So the freshly formed titania aerosol was mixed with a fine spray of octyltriethoxysilane (OTES) in water/ethanol solution and functionalized continuously at high temperature. The extent of functionalization and structure of that surface layer were assessed by thermogravimetric analysis (TGA) coupled to mass spectroscopy (MS), differential scanning calorimetry (DSC), Fourier transform infrared (FTIR), and Raman spectroscopy. Product particles were characterized also by transmission electron microscopy (TEM), X-ray diffraction, and nitrogen adsorption. The influence of titania specific surface area (SSA) and OTES solution concentration on the functional group surface density was investigated. The titanium dioxide surface was covered with functional groups (up to 2.9 wt %) that were thermally stable up to 300 degrees C in air at an average density of 2 OTES/nm(2). Such surface-functionalized particle suspensions in 2-ethylhexanoic acid and xylene were stable over several weeks. In contrast, as-prepared hydrophilic TiO(2) precipitated within days in these solvents.", "doi": "10.1021/la9037149", "pmid": "20192157", "labels": {"Alexandra Teleki": null, "SciLifeLab Fellow": null}, "xrefs": [], "notes": [], "created": "2020-11-30T21:42:29.429Z", "modified": "2022-11-07T11:29:43.606Z"}, {"entity": "publication", "iuid": "bd23b1e488b84f17a0e138a701bffbbb", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/bd23b1e488b84f17a0e138a701bffbbb.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/bd23b1e488b84f17a0e138a701bffbbb"}}, "title": "In situ coating of flame-made TiO2 particles with nanothin SiO2 films.", "authors": [{"family": "Teleki", "given": "Alexandra", "initials": "A"}, {"family": "Heine", "given": "Martin C", "initials": "MC"}, {"family": "Krumeich", "given": "Frank", "initials": "F"}, {"family": "Akhtar", "given": "M Kamal", "initials": "MK"}, {"family": "Pratsinis", "given": "Sotiris E", "initials": "SE"}], "type": "journal article", "published": "2008-11-04", "journal": {"title": "Langmuir", "issn": "0743-7463", "volume": "24", "issue": "21", "pages": "12553-12558", "issn-l": null}, "abstract": "Rutile TiO2 particles made by flame spray pyrolysis (FSP) were coated in a single step with SiO2 layers in an enclosed flame reactor. This in situ particle coating was accomplished by a hollow ring delivering hexamethyldisiloxane (HMDSO) vapor (precursor to SiO2) through multiple jets in swirl cross-flow to Al-doped nanostructured rutile TiO2 aerosol freshly made by FSP of a solution of titanium tetraisopropoxide and aluminum sec-butoxide in xylene. The as-prepared powders were characterized by (scanning) transmission electron microscopy (STEM and TEM), energy dispersive X-ray analysis, X-ray diffraction, nitrogen adsorption, electrophoretic mobility, DC plasma optical emission (DCP-OES), and Fourier transform infrared (FT-IR) spectroscopy. The coating quality was assessed further by the photocatalytic oxidation of isopropyl alcohol to acetone. The effect of HMDSO injection point and vapor concentration on product particle morphology was investigated. The titania particles were uniformly SiO2-coated with controlled and uniform thickness at a production rate of about 30 g h(-1) and exhibited limited, if any, photoactivity. In contrast, spraying and combusting equivalent mixtures of the above Si/Al/Ti precursors in the above reactor (without delivering HMDSO through the hollow ring) resulted in particles segregated in amorphous (SiO2) and crystalline (TiO2) domains which exhibited high photocatalytic activity.", "doi": "10.1021/la801630z", "pmid": "18850688", "labels": {"Alexandra Teleki": null, "SciLifeLab Fellow": null}, "xrefs": [], "notes": [], "created": "2020-11-30T21:42:43.335Z", "modified": "2022-11-07T11:29:43.674Z"}, {"entity": "publication", "iuid": "a8d11537ccd74e8884ad9cd6445dcb27", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/a8d11537ccd74e8884ad9cd6445dcb27.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/a8d11537ccd74e8884ad9cd6445dcb27"}}, "title": "High-pressure liquid dispersion and fragmentation of flame-made silica agglomerates.", "authors": [{"family": "Wengeler", "given": "Robert", "initials": "R"}, {"family": "Teleki", "given": "Alexandra", "initials": "A"}, {"family": "Vetter", "given": "Markus", "initials": "M"}, {"family": "Pratsinis", "given": "Sotiris E", "initials": "SE"}, {"family": "Nirschl", "given": "Hermann", "initials": "H"}], "type": "journal article", "published": "2006-05-23", "journal": {"title": "Langmuir", "issn": "0743-7463", "volume": "22", "issue": "11", "pages": "4928-4935", "issn-l": null}, "abstract": "The influence of primary particle diameter and the degree of agglomeration of flame-made silica agglomerate suspensions in aqueous solutions is studied by high-pressure dispersion (up to 1500 bar) through a nozzle with a 125 microm inner diameter. These particles were produced (4-15 g/h) by oxidation of hexamethyldisiloxane (HMDSO) in a coflow diffusion flame reactor. Their average primary particle size (10-50 nm) and degree of agglomeration were controlled by varying the oxygen and precursor flow rates. The particles were characterized by nitrogen adsorption, electron microscopy, and small-angle X-ray scattering. Hydrodynamic stresses break up soft agglomerates and yield hard agglomerate sizes in the range of 100-180 nm, as characterized by dynamic light scattering. Soft agglomerates exhibited decreasing light scattering diameters with increasing dispersion pressure, while hard agglomerates were insensitive.", "doi": "10.1021/la053283n", "pmid": "16700577", "labels": {"Alexandra Teleki": null, "SciLifeLab Fellow": null}, "xrefs": [], "notes": [], "created": "2020-11-30T21:42:49.388Z", "modified": "2022-11-07T11:29:43.766Z"}], "created": "2018-12-05T09:59:53.202Z", "modified": "2020-11-27T13:12:54.700Z"}