{"entity": "journal", "iuid": "e37b0be153ac4c3a95888f773f358977", "timestamp": "2026-08-20T20:45:19.599Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/journal/Hemasphere.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/journal/Hemasphere"}}, "title": "Hemasphere", "issn": "2572-9241", "issn-l": null, "publications_count": 11, "publications": [{"entity": "publication", "iuid": "a553bf5ddde24f148a888fbdbdc93f07", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/a553bf5ddde24f148a888fbdbdc93f07.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/a553bf5ddde24f148a888fbdbdc93f07"}}, "title": "Disease characteristics and outcomes of acute myeloid leukemia in germline RUNX1 deficiency (Familial Platelet Disorder with associated Myeloid Malignancy).", "authors": [{"family": "Ernst", "given": "Martijn P T", "initials": "MPT", "orcid": "0000-0002-4294-2173", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/aa5764ebc2a1477a8579e34da48027c2.json"}}, {"family": "Versluis", "given": "Jurjen", "initials": "J"}, {"family": "Valk", "given": "Peter J M", "initials": "PJM"}, {"family": "Bierings", "given": "Marc", "initials": "M"}, {"family": "Tamminga", "given": "Rienk Y J", "initials": "RYJ"}, {"family": "Hooimeijer", "given": "Louise H", "initials": "LH"}, {"family": "D\u00f6hner", "given": "Konstanze", "initials": "K", "orcid": "0000-0002-2261-9862", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/50025e7765ee4d9aad4ddadd2540e2af.json"}}, {"family": "Gresele", "given": "Paolo", "initials": "P"}, {"family": "Tawana", "given": "Kiran", "initials": "K"}, {"family": "Langemeijer", "given": "Saskia M C", "initials": "SMC"}, {"family": "Van der Reijden", "given": "Bert A", "initials": "BA"}, {"family": "Podgornik", "given": "Helena", "initials": "H"}, {"family": "Sever", "given": "Matjaz", "initials": "M"}, {"family": "Tvedt", "given": "Tor H A", "initials": "THA"}, {"family": "Vulliamy", "given": "Tom", "initials": "T"}, {"family": "Fitzgibbon", "given": "Jude", "initials": "J"}, {"family": "Dokal", "given": "Inderjeet", "initials": "I"}, {"family": "Baliakas", "given": "Panagiotis", "initials": "P"}, {"family": "Bastida", "given": "Jos\u00e9 M", "initials": "JM"}, {"family": "Pohlkamp", "given": "Christian", "initials": "C"}, {"family": "Haferlach", "given": "Torsten", "initials": "T"}, {"family": "Larcher", "given": "Lise", "initials": "L"}, {"family": "Soulier", "given": "Jean", "initials": "J"}, {"family": "Schutgens", "given": "Roger E G", "initials": "REG", "orcid": "0000-0002-2762-6033", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/ce935a91415e47d6bedf91162d5eee5a.json"}}, {"family": "Freson", "given": "Kathleen", "initials": "K"}, {"family": "Duployez", "given": "Nicolas", "initials": "N", "orcid": "0000-0002-3927-1022", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/4b50451c973b4912b67c62d33b8c466c.json"}}, {"family": "L\u00f6wenberg", "given": "Bob", "initials": "B"}, {"family": "Ericson", "given": "Katrin", "initials": "K"}, {"family": "Cammenga", "given": "J\u00f6rg", "initials": "J"}, {"family": "Ripperger", "given": "Tim", "initials": "T"}, {"family": "Raaijmakers", "given": "Marc H G P", "initials": "MHGP"}], "type": "journal article", "published": "2025-01-00", "journal": {"title": "Hemasphere", "issn": "2572-9241", "volume": "9", "issue": "1", "pages": "e70057", "issn-l": null}, "abstract": "Familial Platelet Disorder with associated Myeloid Malignancy (FPDMM, FPD/AML, RUNX1-FPD), caused by monoallelic deleterious germline RUNX1 variants, is characterized by bleeding diathesis and predisposition for hematologic malignancies, particularly myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Clinical data on FPDMM-associated AML (FPDMM-AML) are limited, complicating evidence-based clinical decision-making. Here, we present retrospective genetic and clinical data of the largest cohort of FPDMM patients reported to date. We describe 159 European patients (from 94 families) of whom 134 were evaluable for the development of malignant disease. Sixty developed a hematologic malignancy (44.8%), most frequently AML (36/134, 26.9%) or MDS (18/134, 13.4%). Somatic alterations of RUNX1 by gene mutation (48%) and chromosome 21 aberrations (14.3%) were the most common somatic genetic aberrations in FPDMM-AML, followed by FLT3-ITD mutations (24.1%). Somatic RUNX1 and FLT3-ITD mutations were not detected in FPDMM-associated MDS, suggesting important contributions to leukemic transformation. Remission-induction chemotherapy resulted in complete remission in 80% of FPDMM-AML patients with a 5-year overall survival (OS) of 50.4%. Survival outcome was non-inferior compared to a large cohort of newly diagnosed adult RUNX1-mutated AML (5-year OS 36.6%, p = 0.5), with relatively infrequent concurrent adverse risk somatic aberrations (ASXL1 mutation, monosomal karyotype, monosomy 5/del 5q) in FPDMM-AML. Collectively, data support the notion that step-wise leukemic evolution in FPDMM is associated with distinct genetic events and indicate that a substantial subset of FPDMM-AML patients achieves prolonged survival with conventional AML treatment, including allogeneic stem cell transplant. These findings are anticipated to inform personalized clinical decision-making in this rare disorder.", "doi": "10.1002/hem3.70057", "pmid": "39822584", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC11735945"}, {"db": "pii", "key": "HEM370057"}], "notes": [], "created": "2026-08-20T06:33:02.037Z", "modified": "2026-08-20T06:33:02.276Z"}, {"entity": "publication", "iuid": "1dd9137538ac47b28ed1a5f71ed960f3", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/1dd9137538ac47b28ed1a5f71ed960f3.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/1dd9137538ac47b28ed1a5f71ed960f3"}}, "title": "PB1709: A COMPLETE DIGITAL KARYOTYPE OF THE B-CELL LEUKEMIA REH CELL LINE RESOLVED BY LONG-READ SEQUENCING", "authors": [{"family": "Wiklander", "given": "Mariya Lysenkova", "initials": "ML"}, {"family": "Arvidsson", "given": "Gustav", "initials": "G"}, {"family": "Bunikis", "given": "Ignas", "initials": "I"}, {"family": "Lundmark", "given": "Anders", "initials": "A"}, {"family": "Raine", "given": "Amanda", "initials": "A"}, {"family": "Marincevic-Zuniga", "given": "Yanara", "initials": "Y"}, {"family": "Gezelius", "given": "Henrik", "initials": "H"}, {"family": "Bremer", "given": "Anna", "initials": "A"}, {"family": "Feuk", "given": "Lars", "initials": "L"}, {"family": "Ameur", "given": "Adam", "initials": "A"}, {"family": "Nordlund", "given": "Jessica", "initials": "J"}], "type": "journal-article", "published": "2023-08-00", "journal": {"issn": "2572-9241", "volume": "7", "issue": "S3", "pages": "e656876f", "title": "Hemasphere", "issn-l": null}, "abstract": null, "doi": "10.1097/01.hs9.0000973704.65687.6f", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T09:52:36.676Z", "modified": "2026-08-20T09:52:36.725Z"}, {"entity": "publication", "iuid": "8bba4561a219407f97478ce7f6f7cbce", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/8bba4561a219407f97478ce7f6f7cbce.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/8bba4561a219407f97478ce7f6f7cbce"}}, "title": "S154: IDENTIFICATION OF NOVEL FACTORS CONTROLLING NON GENETIC CELL PLASTICITY IN CHRONIC MYELOID LEUKEMIA", "authors": [{"family": "Baselli", "given": "Guido", "initials": "G"}, {"family": "Alekseenko", "given": "Alisa", "initials": "A"}, {"family": "Brinkman", "given": "Eva", "initials": "E"}, {"family": "Pareja-Sanchez", "given": "Yerma", "initials": "Y"}, {"family": "Sinanis", "given": "Lefteris", "initials": "L"}, {"family": "Pelechano", "given": "Vicent", "initials": "V"}], "type": "journal-article", "published": "2023-08-00", "journal": {"issn": "2572-9241", "volume": "7", "issue": "S3", "pages": "e08711d7", "title": "Hemasphere", "issn-l": null}, "abstract": null, "doi": "10.1097/01.hs9.0000967528.08711.d7", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T09:52:34.814Z", "modified": "2026-08-20T09:52:34.857Z"}, {"entity": "publication", "iuid": "76391ac1f0fc498a9585b7a8076bb404", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/76391ac1f0fc498a9585b7a8076bb404.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/76391ac1f0fc498a9585b7a8076bb404"}}, "title": "P045: Plasma proteome profiling of cardiotoxicity in patients with Hodgkin lymphoma", "authors": [{"family": "Ulfstedt", "given": "Johan Mattsson", "initials": "JM"}, {"family": "Freyhult", "given": "Eva", "initials": "E"}, {"family": "Christersson", "given": "Christina", "initials": "C"}, {"family": "M\u00f6rth", "given": "Charlott", "initials": "C"}, {"family": "Kamali-Moghaddam", "given": "Masood", "initials": "M"}, {"family": "Eriksson", "given": "Anna", "initials": "A"}, {"family": "Enblad", "given": "Gunilla", "initials": "G"}, {"family": "Molin", "given": "Daniel", "initials": "D"}], "type": "journal-article", "published": "2022-10-00", "journal": {"issn": "2572-9241", "volume": "6", "pages": "20-21", "title": "Hemasphere", "issn-l": null}, "abstract": null, "doi": "10.1097/01.hs9.0000890748.80150.50", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T09:52:33.076Z", "modified": "2026-08-20T09:52:33.091Z"}, {"entity": "publication", "iuid": "de4bfc81159645789762472df78355e3", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/de4bfc81159645789762472df78355e3.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/de4bfc81159645789762472df78355e3"}}, "title": "Five Percent Variant Allele Frequency Is a Reliable Reporting Threshold for TP53 Variants Detected by Next Generation Sequencing in Chronic Lymphocytic Leukemia in the Clinical Setting.", "authors": [{"family": "Pandzic", "given": "Tatjana", "initials": "T"}, {"family": "Ladenvall", "given": "Claes", "initials": "C"}, {"family": "Engvall", "given": "Marie", "initials": "M"}, {"family": "Mattsson", "given": "Mattias", "initials": "M"}, {"family": "Hermanson", "given": "Monica", "initials": "M"}, {"family": "Cavelier", "given": "Lucia", "initials": "L"}, {"family": "Ljungstr\u00f6m", "given": "Viktor", "initials": "V"}, {"family": "Baliakas", "given": "Panagiotis", "initials": "P"}], "type": "journal article", "published": "2022-08-00", "journal": {"title": "Hemasphere", "issn": "2572-9241", "volume": "6", "issue": "8", "pages": "e761", "issn-l": null}, "abstract": "The clinical significance of small TP53 clones detected with next generation sequencing (NGS) in chronic lymphocytic leukemia is an issue of active debate. According to the official guidelines, treatment decisions should be guided only by variants with variant allele frequency (VAF) \u226510%. We present data on 325 consecutive patients with chronic lymphocytic leukemia analyzed with NGS. In total 47 pathogenic/likely pathogenic (P/LP), TP53 variants were detected in 26 patients (8%). Eleven of these (23%) were in the 5% to 10% VAF range and reported according to our institutional policy. All TP53 variants in the 5% to 10% VAF range were confirmed (100% concordance) with a second NGS panel. Our results where further validated with the performance of Sanger sequencing and digital droplet PCR (ddPCR). In 12 patients with available fluorescence in situ hybridization data and TP53 mutations within 5% to 10% VAF, deletion of chromosome 17p (del(17p)) was detectable in only 1 patient. We propose a robust diagnostic algorithm, which allows the safe detection and reporting of TP53 variants with VAF down to 5% in the clinical setting. Our study provides evidence that NGS is equally potent to detect variants with VAF 5% to 10% compared to those with VAF 10% to 15%, highlighting the urgent need for harmonization of NGS methodologies across diagnostic laboratories.", "doi": "10.1097/HS9.0000000000000761", "pmid": "35935605", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC9348859"}], "notes": [], "created": "2026-08-20T09:52:49.276Z", "modified": "2026-08-20T09:52:49.286Z"}, {"entity": "publication", "iuid": "33493618e24b4af5ac1cecd6202c9347", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/33493618e24b4af5ac1cecd6202c9347.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/33493618e24b4af5ac1cecd6202c9347"}}, "title": "P635: TARGETING THE ONE-CARBON METABOLISM AS NOVEL THERAPEUTIC STRATEGY IN CHRONIC LYMPHOCYTIC LEUKEMIA", "authors": [{"family": "Viry", "given": "E", "initials": "E"}, {"family": "Largeot", "given": "A", "initials": "A"}, {"family": "Gonder", "given": "S", "initials": "S"}, {"family": "Chemlal", "given": "S", "initials": "S"}, {"family": "Kiweler", "given": "N", "initials": "N"}, {"family": "Meiser", "given": "J", "initials": "J"}, {"family": "Helleday", "given": "T", "initials": "T"}, {"family": "Moussay", "given": "E", "initials": "E"}, {"family": "Paggetti", "given": "J", "initials": "J"}], "type": "journal-article", "published": "2022-06-00", "journal": {"issn": "2572-9241", "volume": "6", "pages": "533-534", "title": "Hemasphere", "issn-l": null}, "abstract": null, "doi": "10.1097/01.hs9.0000845424.37626.83", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T09:52:31.287Z", "modified": "2026-08-20T09:52:31.332Z"}, {"entity": "publication", "iuid": "47f15dc475024120b8b1993c3814e8cf", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/47f15dc475024120b8b1993c3814e8cf.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/47f15dc475024120b8b1993c3814e8cf"}}, "title": "S167: PREDICTION OF RELAPSE AFTER ALLOGENEIC STEM CELL TRANSPLANTATION USING INDIVIDUALIZED MEASURABLE RESIDUAL DISEASE MARKERS; THE PROSPECTIVE NORDIC STUDY NMDSG14B", "authors": [{"family": "Tobiasson", "given": "M", "initials": "M"}, {"family": "Pandzic", "given": "T", "initials": "T"}, {"family": "Illman", "given": "J", "initials": "J"}, {"family": "Nilsson", "given": "L", "initials": "L"}, {"family": "Westr\u00f6m", "given": "S", "initials": "S"}, {"family": "Sollander", "given": "K", "initials": "K"}, {"family": "Ejerblad", "given": "E", "initials": "E"}, {"family": "Olsnes Kittang", "given": "A", "initials": "A"}, {"family": "Olesen", "given": "G", "initials": "G"}, {"family": "Werlenius", "given": "O", "initials": "O"}, {"family": "Bj\u00f6rklund", "given": "A", "initials": "A"}, {"family": "Wiggh", "given": "J", "initials": "J"}, {"family": "lindholm", "given": "C", "initials": "C"}, {"family": "Lorentz", "given": "F", "initials": "F"}, {"family": "Rasmussen", "given": "B", "initials": "B"}, {"family": "Cammenga", "given": "J", "initials": "J"}, {"family": "Weber", "given": "D", "initials": "D"}, {"family": "Gr\u00f6nn\u00e5s", "given": "D", "initials": "D"}, {"family": "Dimitriou", "given": "M", "initials": "M"}, {"family": "Kyt\u00f6l\u00e4", "given": "S", "initials": "S"}, {"family": "Walldin", "given": "G", "initials": "G"}, {"family": "Ljungman", "given": "P", "initials": "P"}, {"family": "Groenbeck", "given": "K", "initials": "K"}, {"family": "Mielke", "given": "S", "initials": "S"}, {"family": "Jacobsen", "given": "S E", "initials": "SE"}, {"family": "Ebeling", "given": "F", "initials": "F"}, {"family": "Cavelier", "given": "L", "initials": "L"}, {"family": "Smidstrup Friis", "given": "L", "initials": "L"}, {"family": "Dybedal", "given": "I", "initials": "I"}, {"family": "Hellstr\u00f6m-Lindberg", "given": "E", "initials": "E"}], "type": "journal-article", "published": "2022-06-00", "journal": {"issn": "2572-9241", "volume": "6", "pages": "68-69", "title": "Hemasphere", "issn-l": null}, "abstract": null, "doi": "10.1097/01.hs9.0000843560.87168.a9", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T09:52:29.458Z", "modified": "2026-08-20T09:52:29.506Z"}, {"entity": "publication", "iuid": "f97ec168e4324f14b9dab800864039fb", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/f97ec168e4324f14b9dab800864039fb.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/f97ec168e4324f14b9dab800864039fb"}}, "title": "Cytogenetics in Chronic Lymphocytic Leukemia: ERIC Perspectives and Recommendations.", "authors": [{"family": "Baliakas", "given": "Panagiotis", "initials": "P"}, {"family": "Espinet", "given": "Blanca", "initials": "B"}, {"family": "Mellink", "given": "Clemens", "initials": "C"}, {"family": "Jarosova", "given": "Marie", "initials": "M"}, {"family": "Athanasiadou", "given": "Anastasia", "initials": "A"}, {"family": "Ghia", "given": "Paolo", "initials": "P"}, {"family": "Kater", "given": "Arnon P", "initials": "AP"}, {"family": "Oscier", "given": "David", "initials": "D"}, {"family": "Haferlach", "given": "Claudia", "initials": "C"}, {"family": "Stamatopoulos", "given": "Kostas", "initials": "K"}], "type": "journal article", "published": "2022-04-00", "journal": {"title": "Hemasphere", "issn": "2572-9241", "volume": "6", "issue": "4", "pages": "e707", "issn-l": null}, "abstract": "Mounting evidence underscores the clinical value of cytogenetic analysis in chronic lymphocytic leukemia (CLL), particularly as it allows the identification of complex karyotype, that has recently emerged as a prognostic and potentially predictive biomarker. That said, explicit recommendations regarding the methodology and clinical interpretation of either chromosome banding analysis (CBA) or chromosome microarray analysis (CMA) are still lacking. We herein present the consensus of the Cytogenetic Steering Scientific Committee of ERIC, the European Research Initiative on CLL, regarding methodological issues as well as clinical interpretation of CBA/CMA and discuss their relevance in CLL. ERIC considers CBA standardized and feasible for CLL on the condition that standards are met, extending from the use of novel mitogens to the accurate interpretation of the findings. On the other hand, CMA, is also standardized, however, robust data on its clinical utility are still scarce. In conclusion, cytogenetic analysis is not yet mature enough to guide treatment choices in CLL. That notwithstanding, ERIC encourages the wide application of CBA, and potentially also CMA, in clinical trials in order to obtain robust evidence regarding the predictive value of specific cytogenetic profiles towards refining risk stratification and improving the management of patients with CLL.", "doi": "10.1097/HS9.0000000000000707", "pmid": "35392482", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC8984316"}], "notes": [], "created": "2026-08-20T09:52:47.577Z", "modified": "2026-08-20T09:52:47.621Z"}, {"entity": "publication", "iuid": "1e0817ab96fa4838bcf186b6421548d0", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/1e0817ab96fa4838bcf186b6421548d0.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/1e0817ab96fa4838bcf186b6421548d0"}}, "title": "Nordic Guidelines for Germline Predisposition to Myeloid Neoplasms in Adults: Recommendations for Genetic Diagnosis, Clinical Management and Follow-up.", "authors": [{"family": "Baliakas", "given": "Panagiotis", "initials": "P"}, {"family": "Tesi", "given": "Bianca", "initials": "B"}, {"family": "Wartiovaara-Kautto", "given": "Ulla", "initials": "U"}, {"family": "Stray-Pedersen", "given": "Asbj\u00f8rg", "initials": "A"}, {"family": "Friis", "given": "Lone Smidstrup", "initials": "LS"}, {"family": "Dybedal", "given": "Ingunn", "initials": "I"}, {"family": "Hovland", "given": "Randi", "initials": "R"}, {"family": "Jahnukainen", "given": "Kirsi", "initials": "K"}, {"family": "Raaschou-Jensen", "given": "Klas", "initials": "K"}, {"family": "Ljungman", "given": "Per", "initials": "P"}, {"family": "Rustad", "given": "Cecilie F", "initials": "CF"}, {"family": "Lautrup", "given": "Charlotte K", "initials": "CK"}, {"family": "Kilpivaara", "given": "Outi", "initials": "O"}, {"family": "Kittang", "given": "Astrid Olsnes", "initials": "AO"}, {"family": "Gr\u00f8nb\u00e6k", "given": "Kirsten", "initials": "K"}, {"family": "Cammenga", "given": "J\u00f6rg", "initials": "J"}, {"family": "Hellstr\u00f6m-Lindberg", "given": "Eva", "initials": "E"}, {"family": "Andersen", "given": "Mette K", "initials": "MK"}], "type": "journal article", "published": "2019-12-00", "journal": {"title": "Hemasphere", "issn": "2572-9241", "volume": "3", "issue": "6", "pages": "e321", "issn-l": null}, "abstract": "Myeloid neoplasms (MNs) with germline predisposition have recently been recognized as novel entities in the latest World Health Organization (WHO) classification for MNs. Individuals with MNs due to germline predisposition exhibit increased risk for the development of MNs, mainly acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Setting the diagnosis of MN with germline predisposition is of crucial clinical significance since it may tailor therapy, dictate the selection of donor for allogeneic hematopoietic stem cell transplantation (allo-HSCT), determine the conditioning regimen, enable relevant prophylactic measures and early intervention or contribute to avoid unnecessary or even harmful medication. Finally, it allows for genetic counseling and follow-up of at-risk family members. Identification of these patients in the clinical setting is challenging, as there is no consensus due to lack of evidence regarding the criteria defining the patients who should be tested for these conditions. In addition, even in cases with a strong suspicion of a MN with germline predisposition, no standard diagnostic algorithm is available. We present the first version of the Nordic recommendations for diagnostics, surveillance and management including considerations for allo-HSCT for patients and carriers of a germline mutation predisposing to the development of MNs.", "doi": "10.1097/HS9.0000000000000321", "pmid": "31976490", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC6924562"}, {"db": "pii", "key": "HemaSphere-2019-0172"}], "notes": [], "created": "2026-08-20T09:52:45.945Z", "modified": "2026-08-20T09:52:45.958Z"}, {"entity": "publication", "iuid": "1862c05710c843a2846a6c165dae881d", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/1862c05710c843a2846a6c165dae881d.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/1862c05710c843a2846a6c165dae881d"}}, "title": "S843 THE PROLIFERATIVE HISTORY SHAPES THE DNA METHYLOME OF B\u2010CELL TUMORS AND PREDICTS CLINICAL OUTCOME", "authors": [{"family": "Duran\u2010Ferrer", "given": "M", "initials": "M"}, {"family": "Clot", "given": "G", "initials": "G"}, {"family": "Nadeu", "given": "F", "initials": "F"}, {"family": "Beekman", "given": "R", "initials": "R"}, {"family": "Baumann", "given": "T", "initials": "T"}, {"family": "Nordlund", "given": "J", "initials": "J"}, {"family": "Marincevic\u2010Zuniga", "given": "Y", "initials": "Y"}, {"family": "Rivas\u2010Delgado", "given": "A", "initials": "A"}, {"family": "Ordo\u00f1ez", "given": "R", "initials": "R"}, {"family": "Castellano", "given": "G", "initials": "G"}, {"family": "Kulis", "given": "M", "initials": "M"}, {"family": "Queir\u00f3s", "given": "A", "initials": "A"}, {"family": "Seung\u2010Tae", "given": "L", "initials": "L"}, {"family": "Wiemels", "given": "J", "initials": "J"}, {"family": "Royo", "given": "R", "initials": "R"}, {"family": "Puiggr\u00f3s", "given": "M", "initials": "M"}, {"family": "Torrents", "given": "D", "initials": "D"}, {"family": "Gin\u00e9", "given": "E", "initials": "E"}, {"family": "Be\u00e0", "given": "S", "initials": "S"}, {"family": "Jares", "given": "P", "initials": "P"}, {"family": "Agirre", "given": "X", "initials": "X"}, {"family": "Prosper", "given": "F", "initials": "F"}, {"family": "L\u00f3pez\u2010Ot\u00edn", "given": "C", "initials": "C"}, {"family": "Puente", "given": "X S", "initials": "XS"}, {"family": "Delgado", "given": "J", "initials": "J"}, {"family": "L\u00f3pez\u2010Guillermo", "given": "A", "initials": "A"}, {"family": "Campo", "given": "E", "initials": "E"}, {"family": "Mart\u00edn\u2010Subero", "given": "J I", "initials": "JI"}], "type": "journal-article", "published": "2019-06-00", "journal": {"title": "Hemasphere", "issn": "2572-9241", "volume": "3", "issue": "S1", "pages": "376", "issn-l": null}, "abstract": null, "doi": "10.1097/01.hs9.0000561652.34864.a1", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T09:52:27.654Z", "modified": "2026-08-20T09:52:27.707Z"}, {"entity": "publication", "iuid": "557306d1c085472d846f4cb23c66b540", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/557306d1c085472d846f4cb23c66b540.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/557306d1c085472d846f4cb23c66b540"}}, "title": "PF230 THE RNA HELICASE DDX17 PROTECTS ACUTE MYELOID LEUKEMIA CELLS AGAINST DNA DAMAGE", "authors": [{"family": "Jagdhane", "given": "P", "initials": "P"}, {"family": "Garg", "given": "S", "initials": "S"}, {"family": "Xia", "given": "J", "initials": "J"}, {"family": "He", "given": "L", "initials": "L"}, {"family": "Misiak", "given": "D", "initials": "D"}, {"family": "Mortusewicz", "given": "O", "initials": "O"}, {"family": "Helleday", "given": "T", "initials": "T"}, {"family": "M\u00fcller\u2010Tidow", "given": "C", "initials": "C"}, {"family": "Koehn", "given": "M", "initials": "M"}, {"family": "Pabst", "given": "C", "initials": "C"}], "type": "journal-article", "published": "2019-06-00", "journal": {"title": "Hemasphere", "issn": "2572-9241", "volume": "3", "issue": "S1", "pages": "67", "issn-l": null}, "abstract": null, "doi": "10.1097/01.hs9.0000559136.77382.94", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T09:52:25.900Z", "modified": "2026-08-20T09:52:25.943Z"}], "created": "2026-08-20T06:33:02.240Z", "modified": "2026-08-20T06:33:02.240Z"}