{"entity": "journal", "iuid": "3133153abc3142c9b7674bf826fdc78b", "timestamp": "2026-08-26T22:46:27.630Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/journal/Clin%20Res%20Cardiol.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/journal/Clin%20Res%20Cardiol"}}, "title": "Clin Res Cardiol", "issn": "1861-0692", "issn-l": null, "publications_count": 1, "publications": [{"entity": "publication", "iuid": "a299c5f2c2454a05878405305868b7a3", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/a299c5f2c2454a05878405305868b7a3.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/a299c5f2c2454a05878405305868b7a3"}}, "title": "Compared with matched controls, patients with postoperative atrial fibrillation (POAF) have increased long-term AF after CABG, and POAF is further associated with increased ischemic stroke, heart failure and mortality even after adjustment for AF.", "authors": [{"family": "Thor\u00e9n", "given": "Emma", "initials": "E", "orcid": "0000-0002-3193-7643", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b8801e0292e04c96aa534528bbe44f6e.json"}}, {"family": "Wernroth", "given": "Mona-Lisa", "initials": "ML", "orcid": "0000-0002-8845-8846", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/228e6d16e2e44389b0dc548584616a70.json"}}, {"family": "Christersson", "given": "Christina", "initials": "C", "orcid": "0000-0001-9116-8084", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/85a0a296958d40d18f2f5a73afa1c40d.json"}}, {"family": "Grinnemo", "given": "Karl-Henrik", "initials": "KH", "orcid": "0000-0001-6717-3393", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/cdd79656089b4831852188f53d094e32.json"}}, {"family": "Jid\u00e9us", "given": "Lena", "initials": "L"}, {"family": "St\u00e5hle", "given": "Elisabeth", "initials": "E", "orcid": "0000-0003-3086-4064", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1cb8d1b3342c464cbe1d583e63556888.json"}}], "type": "journal article", "published": "2020-10-00", "journal": {"title": "Clin Res Cardiol", "issn": "1861-0692", "volume": "109", "issue": "10", "pages": "1232-1242", "issn-l": null}, "abstract": "To analyze (1) associations between postoperative atrial fibrillation (POAF) after CABG and long-term cardiovascular outcome, (2) whether associations were influenced by AF during follow-up, and (3) if morbidities associated with POAF contribute to mortality.\n\nAn observational cohort study of 7145 in-hospital survivors after isolated CABG (1996-2012), with preoperative sinus rhythm and without AF history. Incidence of AF was compared with matched controls. Time-updated covariates were used to adjust for POAF-related morbidities during follow-up, including AF.\n\nThirty-one percent of patients developed POAF. Median follow-up was 9.8 years. POAF patients had increased AF compared with matched controls (HR 3.03; 95% CI 2.66-3.49), while AF occurrence in non-POAF patients was similar to controls (1.00; 0.89-1.13). The observed AF increase among POAF patients compared with controls persisted over time (> 10 years 2.73; 2.13-3.51). Conversely, the non-POAF cohort showed no AF increase beyond the first postoperative year. Further, POAF was associated with long-term AF (adjusted HR 3.20; 95% CI 2.73-3.76), ischemic stroke (1.23; 1.06-1.42), heart failure (1.44; 1.27-1.63), overall mortality (1.21; 1.11-1.32), cardiac mortality (1.35; 1.18-1.54), and cerebrovascular mortality (1.54; 1.17-2.02). These associations remained after adjustment for AF during follow-up. Adjustment for other POAF-associated morbidities weakened the association between POAF and overall mortality, which became non-significant.\n\nPatients with POAF after CABG had three times the incidence of long-term AF compared with both non-POAF patients and matched controls. POAF was associated with long-term ischemic stroke, heart failure, and corresponding mortality even after adjustment for AF during follow-up. The increased overall mortality was partly explained by morbidities associated with POAF.", "doi": "10.1007/s00392-020-01614-z", "pmid": "32036429", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC7515855"}, {"db": "pii", "key": "10.1007/s00392-020-01614-z"}], "notes": [], "created": "2026-08-21T11:06:33.689Z", "modified": "2026-08-21T11:06:33.916Z"}], "created": "2026-08-21T11:06:33.878Z", "modified": "2026-08-21T11:06:33.878Z"}