{"entity": "journal", "iuid": "c4da4ddfec3d4a68abdbf5d06ba96a71", "timestamp": "2026-08-20T20:45:17.838Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/journal/ChemSusChem.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/journal/ChemSusChem"}}, "title": "ChemSusChem", "issn": "1864-564X", "issn-l": null, "publications_count": 4, "publications": [{"entity": "publication", "iuid": "1fb121142bc844809f57c4726a2fd03a", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/1fb121142bc844809f57c4726a2fd03a.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/1fb121142bc844809f57c4726a2fd03a"}}, "title": "Fast Depolymerization of PET Bottle Mediated by Microwave Pre-Treatment and An Engineered PETase.", "authors": [{"family": "Guo", "given": "Boyang", "initials": "B", "orcid": "0000-0001-5510-1392", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/be843859e5a34c66b2c914c6f2bb955f.json"}}, {"family": "Lopez-Lorenzo", "given": "Ximena", "initials": "X", "orcid": "0000-0002-4708-9861", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/49eec96b36fd4880b09564c0b7688932.json"}}, {"family": "Fang", "given": "Yuan", "initials": "Y"}, {"family": "B\u00e4ckstr\u00f6m", "given": "Eva", "initials": "E"}, {"family": "Capezza", "given": "Antonio Jose", "initials": "AJ"}, {"family": "Vanga", "given": "Sudarsan Reddy", "initials": "SR"}, {"family": "Fur\u00f3", "given": "Istv\u00e1n", "initials": "I"}, {"family": "Hakkarainen", "given": "Minna", "initials": "M", "orcid": "0000-0002-7790-8987", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9d855814ea154871b096568c3e1d66a6.json"}}, {"family": "Syr\u00e9n", "given": "Per-Olof", "initials": "PO", "orcid": "0000-0002-4066-2776", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b035f26bd71e42f9942f9a4943ed0d1a.json"}}], "type": "journal article", "published": "2023-09-22", "journal": {"title": "ChemSusChem", "issn": "1864-564X", "volume": "16", "issue": "18", "pages": "e202300742", "issn-l": null}, "abstract": "Recycling plastics is the key to reaching a sustainable materials economy. Biocatalytic degradation of plastics shows great promise by allowing selective depolymerization of man-made materials into constituent building blocks under mild aqueous conditions. However, insoluble plastics have polymer chains that can reside in different conformations and show compact secondary structures that offer low accessibility for initiating the depolymerization reaction by enzymes. In this work, we overcome these shortcomings by microwave irradiation as a pre-treatment process to deliver powders of polyethylene terephthalate (PET) particles suitable for subsequent biotechnology-assisted plastic degradation by previously generated engineered enzymes. An optimized microwave step resulted in 1400 times higher integral of released terephthalic acid (TPA) from high-performance liquid chromatography (HPLC), compared to original untreated PET bottle. Biocatalytic plastic hydrolysis of substrates originating from PET bottles responded to 78 % yield conversion from 2 h microwave pretreatment and 1 h enzymatic reaction at 30 \u00b0C. The increase in activity stems from enhanced substrate accessibility from the microwave step, followed by the administration of designer enzymes capable of accommodating oligomers and shorter chains released in a productive conformation.", "doi": "10.1002/cssc.202300742", "pmid": "37384425", "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T06:31:57.604Z", "modified": "2026-08-20T06:31:57.734Z"}, {"entity": "publication", "iuid": "56833404aab9402582ae4be726e561f8", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/56833404aab9402582ae4be726e561f8.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/56833404aab9402582ae4be726e561f8"}}, "title": "Fast Depolymerization of PET Bottle Mediated by Microwave Pre-Treatment and An Engineered PETase.", "authors": [{"family": "Guo", "given": "Boyang", "initials": "B"}, {"family": "Lopez-Lorenzo", "given": "Ximena", "initials": "X"}, {"family": "Fang", "given": "Yuan", "initials": "Y"}, {"family": "B\u00e4ckstr\u00f6m", "given": "Eva", "initials": "E"}, {"family": "Capezza", "given": "Antonio Jose", "initials": "AJ"}, {"family": "Vanga", "given": "Sudarsan Reddy", "initials": "SR"}, {"family": "Fur\u00f3", "given": "Istv\u00e1n", "initials": "I"}, {"family": "Hakkarainen", "given": "Minna", "initials": "M"}, {"family": "Syr\u00e9n", "given": "Per-Olof", "initials": "PO", "orcid": "0000-0002-4066-2776", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b035f26bd71e42f9942f9a4943ed0d1a.json"}}], "type": "journal article", "published": "2023-09-22", "journal": {"title": "ChemSusChem", "issn": "1864-564X", "volume": "16", "issue": "18", "pages": "e202301237", "issn-l": null}, "abstract": "Invited for this month's cover is the groups of Prof. Minna Hakkarainen, Prof. Istv\u00e1n Fur\u00f3 and Assoc. Prof. Per-Olof Syr\u00e9n at KTH Royal Institute of Technology. The image shows how microwave irradiation is an efficient pre-treatment method of polyethylene terephthalate (PET) for subsequent biocatalytic depolymerization. The Research Article itself is available at 10.1002/cssc.202300742.", "doi": "10.1002/cssc.202301237", "pmid": "37679097", "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T06:31:59.531Z", "modified": "2026-08-20T06:31:59.605Z"}, {"entity": "publication", "iuid": "c7f0be383e3244a38fe4fa8c44712ccd", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/c7f0be383e3244a38fe4fa8c44712ccd.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/c7f0be383e3244a38fe4fa8c44712ccd"}}, "title": "Front Cover: Fast Depolymerization of PET Bottle Mediated by Microwave Pre\u2010Treatment and An Engineered PETase (ChemSusChem 18/2023)", "authors": [{"family": "Guo", "given": "Boyang", "initials": "B", "orcid": "0000-0001-5510-1392", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/be843859e5a34c66b2c914c6f2bb955f.json"}}, {"family": "Lopez\u2010Lorenzo", "given": "Ximena", "initials": "X", "orcid": "0000-0002-4708-9861", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/49eec96b36fd4880b09564c0b7688932.json"}}, {"family": "Fang", "given": "Yuan", "initials": "Y"}, {"family": "B\u00e4ckstr\u00f6m", "given": "Eva", "initials": "E"}, {"family": "Capezza", "given": "Antonio Jose", "initials": "AJ"}, {"family": "Vanga", "given": "Sudarsan Reddy", "initials": "SR"}, {"family": "Fur\u00f3", "given": "Istv\u00e1n", "initials": "I"}, {"family": "Hakkarainen", "given": "Minna", "initials": "M", "orcid": "0000-0002-7790-8987", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/9d855814ea154871b096568c3e1d66a6.json"}}, {"family": "Syr\u00e9n", "given": "Per\u2010Olof", "initials": "P", "orcid": "0000-0002-4066-2776", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b035f26bd71e42f9942f9a4943ed0d1a.json"}}], "type": "journal-article", "published": "2023-09-22", "journal": {"title": "ChemSusChem", "issn": "1864-564X", "volume": "16", "issue": "18", "issn-l": null}, "abstract": null, "doi": "10.1002/cssc.202301238", "pmid": null, "labels": [], "xrefs": [], "notes": [], "created": "2026-08-20T06:32:06.636Z", "modified": "2026-08-20T06:32:06.715Z"}, {"entity": "publication", "iuid": "b9149930663e43008ad85667ff1f72d9", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/b9149930663e43008ad85667ff1f72d9.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/b9149930663e43008ad85667ff1f72d9"}}, "title": "Biocatalysis in the Recycling Landscape for Synthetic Polymers and Plastics towards Circular Textiles.", "authors": [{"family": "J\u00f6nsson", "given": "Christina", "initials": "C", "orcid": "0000-0003-3124-1723", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/00a9f7e064a7479aa2dea0e0363b3077.json"}}, {"family": "Wei", "given": "Ren", "initials": "R"}, {"family": "Biundo", "given": "Antonino", "initials": "A"}, {"family": "Landberg", "given": "Johan", "initials": "J"}, {"family": "Schwarz Bour", "given": "Lisa", "initials": "L"}, {"family": "Pezzotti", "given": "Fabio", "initials": "F"}, {"family": "Toca", "given": "Andreea", "initials": "A"}, {"family": "M Jacques", "given": "Les", "initials": "L"}, {"family": "Bornscheuer", "given": "Uwe T", "initials": "UT", "orcid": "0000-0003-0685-2696", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/0464afedde7643f19b28b66fb3497017.json"}}, {"family": "Syr\u00e9n", "given": "Per-Olof", "initials": "PO", "orcid": "0000-0002-4066-2776", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/b035f26bd71e42f9942f9a4943ed0d1a.json"}}], "type": "journal article", "published": "2021-10-05", "journal": {"title": "ChemSusChem", "issn": "1864-564X", "volume": "14", "issue": "19", "pages": "4028-4040", "issn-l": null}, "abstract": "Although recovery of fibers from used textiles with retained material quality is desired, separation of individual components from polymer blends used in today's complex textile materials is currently not available at viable scale. Biotechnology could provide a solution to this pressing problem by enabling selective depolymerization of recyclable fibers of natural and synthetic origin, to isolate constituents or even recover monomers. We compiled experimental data for biocatalytic polymer degradation with a focus on synthetic polymers with hydrolysable links and calculated conversion rates to explore this path The analysis emphasizes that we urgently need major research efforts: beyond cellulose-based fibers, biotechnological-assisted depolymerization of plastics so far only works for polyethylene terephthalate, with degradation of a few other relevant synthetic polymer chains being reported. In contrast, by analyzing market data and emerging trends for synthetic fibers in the textile industry, in combination with numbers from used garment collection and sorting plants, it was shown that the use of difficult-to-recycle blended materials is rapidly growing. If the lack of recycling technology and production trend for fiber blends remains, a volume of more than 3400 Mt of waste will have been accumulated by 2030. This work highlights the urgent need to transform the textile industry from a biocatalytic perspective.", "doi": "10.1002/cssc.202002666", "pmid": "33497036", "labels": [], "xrefs": [{"db": "pmc", "key": "PMC8518944"}], "notes": [], "created": "2026-08-20T06:31:55.037Z", "modified": "2026-08-20T06:31:55.204Z"}], "created": "2026-08-20T06:31:55.164Z", "modified": "2026-08-20T06:31:55.164Z"}