{"entity": "journal", "iuid": "963c9c8950084287abff5ffb5e5f49c7", "timestamp": "2026-09-26T23:02:19.029Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/journal/Breast.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/journal/Breast"}}, "title": "Breast", "issn": "1532-3080", "issn-l": null, "publications_count": 2, "publications": [{"entity": "publication", "iuid": "34e932a5f5df4276a9396e3cdcc0ee2a", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/34e932a5f5df4276a9396e3cdcc0ee2a.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/34e932a5f5df4276a9396e3cdcc0ee2a"}}, "title": "Potential gain in life years for Swedish women with breast cancer if stage and survival differences between education groups could be eliminated - Three what-if scenarios.", "authors": [{"family": "Bower", "given": "Hannah", "initials": "H"}, {"family": "Andersson", "given": "Therese M-L", "initials": "TM"}, {"family": "Syriopoulou", "given": "Elisavet", "initials": "E"}, {"family": "Rutherford", "given": "Mark J", "initials": "MJ"}, {"family": "Lambe", "given": "Mats", "initials": "M"}, {"family": "Ahlgren", "given": "Johan", "initials": "J"}, {"family": "Dickman", "given": "Paul W", "initials": "PW"}, {"family": "Lambert", "given": "Paul C", "initials": "PC"}], "type": "evaluation study", "published": "2019-06-00", "journal": {"title": "Breast", "issn": "1532-3080", "volume": "45", "pages": "75-81", "issn-l": null}, "abstract": "Many studies have found evidence of socioeconomic differences in breast cancer survival. This study aimed to quantify the impact of removing differences in stage distribution and stage-specific relative survival between education groups in Swedish women with breast cancer. Using information from a breast cancer research database, the study population contained 62 121 women diagnosed with breast cancer in three healthcare regions of Sweden from 1992 to 2012. The loss in expectation of life and life years lost due to breast cancer were estimated using flexible parametric relative survival models by education group and age at diagnosis. The potential gain in life years and postponable deaths were calculated by applying the 1) stage distribution, 2) stage-specific relative survival, and 3) both stage distribution and stage-specific relative survival of the high education group to the low and medium education groups. For a cohort of around 3500 women diagnosed with breast cancer residing in three Swedish healthcare regions in a typical calendar year, we estimated that removing stage differences would postpone an additional 25 deaths at five years after diagnosis, and result in a gain of approximately 573 life years. Alternatively, if stage-specific breast cancer survival could be equated, approximately 692 life years could be saved and an additional 26 deaths could be postponed five years after diagnosis. Results such as these can help guide decisions on interventions intended to minimise socioeconomic differences in breast cancer outcomes.", "doi": "10.1016/j.breast.2019.03.005", "pmid": "30904700", "labels": [], "xrefs": [{"db": "pii", "key": "S0960-9776(19)30044-X"}], "notes": [], "created": "2026-09-23T12:40:47.651Z", "modified": "2026-09-23T12:40:49.259Z"}, {"entity": "publication", "iuid": "f8e827a1bead44c4b4723fe2c653044d", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/f8e827a1bead44c4b4723fe2c653044d.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/f8e827a1bead44c4b4723fe2c653044d"}}, "title": "Causes of sick leave, disability pension, and death following a breast cancer diagnosis in women of working age.", "authors": [{"family": "Plym", "given": "Anna", "initials": "A"}, {"family": "Johansson", "given": "Anna L V", "initials": "ALV"}, {"family": "Bower", "given": "Hannah", "initials": "H"}, {"family": "Voss", "given": "Margaretha", "initials": "M"}, {"family": "Holmberg", "given": "Lars", "initials": "L"}, {"family": "Fredriksson", "given": "Irma", "initials": "I"}, {"family": "Lambe", "given": "Mats", "initials": "M"}], "type": "journal article", "published": "2019-06-00", "journal": {"title": "Breast", "issn": "1532-3080", "volume": "45", "pages": "48-55", "issn-l": null}, "abstract": "Women diagnosed with breast cancer during working age are at increased risk of permanent absence from work, but the underlying medical causes have rarely been studied. We examined the risk of cause-specific sick leave, disability pension, and the competing event death after a breast cancer diagnosis in a population-based cohort study.\n\nFrom the Breast Cancer Data Base Sweden, we identified 16,603 women diagnosed with stage I-III breast cancer between 2000 and 2012, and 63,773 control women. Using multi-state modelling, we calculated probabilities and durations of sick leave, disability pension, and death by registered cause, together with cause-specific hazard ratios.\n\nFive years after diagnosis, causes other than cancer accounted for around half of all sick leave (3.5% out of 6.8% of women) and disability pension (1.4% out of 2.6%) in women with breast cancer. Compared with control women, women with breast cancer were at increased risk of sick leave and disability pension due to mental disorders (HR 1.24, 95% CI 1.15-1.33 and HR 1.54, 95% CI 1.29-1.85, respectively) and disability pension due to inflammatory diseases (HR 1.46, 95% CI 1.05-2.03). The risk of sick leave and disability pension due to cardiovascular disease was also elevated, although only statistically significant for disability pension in women diagnosed after 2005 (HR 2.24, 95% CI 1.22-4.13).\n\nFollow-up, support, and rehabilitation programs for women diagnosed with breast cancer must address a wide range of psychological and physical conditions to limit the consequences on working life.", "doi": "10.1016/j.breast.2019.02.012", "pmid": "30852409", "labels": [], "xrefs": [{"db": "pii", "key": "S0960-9776(19)30039-6"}], "notes": [], "created": "2026-09-23T11:56:01.827Z", "modified": "2026-09-23T11:56:01.872Z"}], "created": "2026-09-23T11:56:01.836Z", "modified": "2026-09-23T11:56:01.836Z"}