{"entity": "journal", "iuid": "ffad82d7752244d1a879153fd92b66c3", "timestamp": "2026-03-10T03:10:06.926Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/journal/Biol%20Trace%20Elem%20Res.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/journal/Biol%20Trace%20Elem%20Res"}}, "title": "Biol Trace Elem Res", "issn": "1559-0720", "issn-l": "0163-4984", "publications_count": 2, "publications": [{"entity": "publication", "iuid": "3ae4c17393104f42a6c63d35d2616f52", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/3ae4c17393104f42a6c63d35d2616f52.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/3ae4c17393104f42a6c63d35d2616f52"}}, "title": "Safety Assessments of Nickel Boride Nanoparticles on the Human Pulmonary Alveolar Cells by Using Cell Viability and Gene Expression Analyses.", "authors": [{"family": "T\u00fcrkez", "given": "Hasan", "initials": "H"}, {"family": "Arslan", "given": "Mehmet Enes", "initials": "ME", "orcid": "0000-0002-1600-2305", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/6c5dd8a766b948efa5f040ceb43e60a6.json"}}, {"family": "S\u00f6nmez", "given": "Erdal", "initials": "E"}, {"family": "Tatar", "given": "Abdulgani", "initials": "A"}, {"family": "Geyiko\u011flu", "given": "Fatime", "initials": "F"}, {"family": "A\u00e7ikyildiz", "given": "Metin", "initials": "M"}, {"family": "Mardino\u011flu", "given": "Adil", "initials": "A"}], "type": "journal article", "published": "2021-07-00", "journal": {"title": "Biol Trace Elem Res", "issn": "1559-0720", "issn-l": "0163-4984", "volume": "199", "issue": "7", "pages": "2602-2611"}, "abstract": "Nickel boride is generally used in the steel industry as a melting accelerator due to its feature of creating a protective and stable attribute at high temperatures. It is also used to improve the hardenability of the steel with boron addition in the production. Thus, safety studies and biocompatibility analysis of nickel boride should be performed comprehensively to understand the limitations of use in various areas. In the present study, nickel boride nanoparticles (Ni2B NPs) were synthesized by a single-step method and molecule characterizations were performed via the use of X-ray diffraction analysis (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), and energy dispersive X-ray (EDX) analyses. Cytotoxicity properties of Ni2B NPs were identified on human pulmonary alveolar epithelial cells (HPAEpiC) by using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), neutral red (NR), and lactate dehydrogenase (LDH) assays. Illumina human ht-12 v4.0 whole-genome microarray analysis was conducted to investigate NiB2 NPs effects on gene expression regulations of HPAEpiC cells. The database for annotation, visualization, and integrated discovery (DAVID) analysis was performed to reveal the relationship between Ni2B NP application and cellular pathway alterations. According to cytotoxicity analysis, the IC50 value for Ni2B NP application was found as 81.99 mg/L concentration. Microarray analysis of Ni2B NP application was shown for the first time that 693 gene expression changes (FC \u2265 2) occurred significantly over 40.000 gene probes and Ni2B NPs were observed to affect microtubule regulation, centrosome organization, and phosphoprotein synthesis.", "doi": "10.1007/s12011-020-02374-7", "pmid": "32909113", "labels": {"Adil Mardinoglu": null, "SciLifeLab Fellow": null}, "xrefs": [{"db": "pii", "key": "10.1007/s12011-020-02374-7"}], "notes": [], "created": "2020-11-30T03:13:21.411Z", "modified": "2022-11-04T11:32:12.905Z"}, {"entity": "publication", "iuid": "d4ec600d41c64ef49cc5dd8093a7fd18", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/d4ec600d41c64ef49cc5dd8093a7fd18.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/d4ec600d41c64ef49cc5dd8093a7fd18"}}, "title": "Mercury Human Exposure in Populations Living Around Lake Tana (Ethiopia).", "authors": [{"family": "Habiba", "given": "G", "initials": "G"}, {"family": "Abebe", "given": "G", "initials": "G"}, {"family": "Bravo", "given": "Andrea G", "initials": "AG"}, {"family": "Ermias", "given": "D", "initials": "D"}, {"family": "Staffan", "given": "\u01fa", "initials": "\u01fa"}, {"family": "Bishop", "given": "K", "initials": "K"}], "type": "journal article", "published": "2017-02-00", "journal": {"title": "Biol Trace Elem Res", "issn": "1559-0720", "volume": "175", "issue": "2", "pages": "237-243", "issn-l": "0163-4984"}, "abstract": "A survey carried out in Lake Tana in 2015 found that Hg levels in some fish species exceeded internationally accepted safe levels for fish consumption. The current study assesses human exposure to Hg through fish consumption around the Lake Tana. Of particular interest was that a dietary intake of fishes is currently a health risk for Bihar Dar residents and anglers. Hair samples were collected from three different groups: anglers, college students and teachers, and daily laborers. A questionary includes gender, age, weight, activity. Frequency of fish consumption and origin of the eaten fish were completed by each participant. Mercury concentrations in hair were significantly higher (P value <0.05) for anglers (mean\u2009\u00b1\u2009standard deviation 0.120\u2009\u00b1\u20090.199\u00a0\u03bcg/g) than college students (mean\u2009\u00b1\u2009standard deviation 0.018\u2009\u00b1\u20090.039\u00a0\u03bcg/g) or daily workers (mean\u2009\u00b1\u2009standard deviation 16\u2009\u00b1\u20099.5\u00a0ng/g). Anglers consumed fish more often than daily workers and college group. Moreover, there was also a strong correlation (P value <0.05) between the logarithms of total mercury and age associated with mercury concentration in scalp hair. Mercury concentrations in the hair of men were on average twice the value of the women. Also, users of skin lightening soap on a daily basis had 2.5 times greater mercury in scalp hair than non-users. Despite the different sources of mercury exposure mentioned above, the mercury concentrations of the scalp hair of participants of this study were below levels deemed to pose a threat to health.", "doi": "10.1007/s12011-016-0745-9", "pmid": "27278962", "labels": {"Affiliated researcher": null}, "xrefs": [{"db": "pii", "key": "10.1007/s12011-016-0745-9"}], "notes": [], "created": "2018-12-05T11:59:44.356Z", "modified": "2018-12-05T11:59:44.387Z"}], "created": "2018-12-05T11:59:44.370Z", "modified": "2020-11-27T13:12:55.772Z"}