{"entity": "journal", "iuid": "497d29d8724241d6938ca64335b9890a", "timestamp": "2026-09-23T21:35:19.951Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/journal/Behav%20Res%20Ther.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/journal/Behav%20Res%20Ther"}}, "title": "Behav Res Ther", "issn": "1873-622X", "issn-l": null, "publications_count": 3, "publications": [{"entity": "publication", "iuid": "dad8f39384e848c8b14a084ab0f86084", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/dad8f39384e848c8b14a084ab0f86084.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/dad8f39384e848c8b14a084ab0f86084"}}, "title": "To sleep or not to sleep, that is the question: A systematic review and meta-analysis on the effect of post-trauma sleep on intrusive memories of analog trauma.", "authors": [{"family": "Sch\u00e4fer", "given": "Sarah K", "initials": "SK"}, {"family": "L\u00fcder", "given": "Charina C", "initials": "CC"}, {"family": "Porcheret", "given": "Kate", "initials": "K"}, {"family": "Hu", "given": "Xiaoqing", "initials": "X"}, {"family": "Margraf", "given": "J\u00fcrgen", "initials": "J"}, {"family": "Michael", "given": "Tanja", "initials": "T"}, {"family": "Holmes", "given": "Emily A", "initials": "EA"}, {"family": "Werner", "given": "Gabriela G", "initials": "GG"}, {"family": "Wilhelm", "given": "Ines", "initials": "I"}, {"family": "Woud", "given": "Marcella L", "initials": "ML"}, {"family": "Zeng", "given": "Shengzi", "initials": "S"}, {"family": "Friesen", "given": "Edith", "initials": "E"}, {"family": "Haim-Nachum", "given": "Shilat", "initials": "S"}, {"family": "Lass-Hennemann", "given": "Johanna", "initials": "J"}, {"family": "Lieb", "given": "Klaus", "initials": "K"}, {"family": "Kunzler", "given": "Angela M", "initials": "AM"}, {"family": "Wirth", "given": "Benedikt E", "initials": "BE"}, {"family": "Sopp", "given": "M Roxanne", "initials": "MR"}], "type": "meta-analysis", "published": "2023-08-00", "journal": {"title": "Behav Res Ther", "issn": "1873-622X", "volume": "167", "pages": "104359", "issn-l": null}, "abstract": "Distressing intrusive memories of a traumatic event are one of the hallmark symptoms of posttraumatic stress disorder. Thus, it is crucial to identify early interventions that prevent the occurrence of intrusive memories. Both, sleep and sleep deprivation have been discussed as such interventions, yet previous studies yielded contradicting effects. Our systematic review aims at evaluating existing evidence by means of traditional and individual participant data (IPD) meta-analyses to overcome power issues of sleep research. Until May 16th, 2022, six databases were searched for experimental analog studies examining the effect of post-trauma sleep versus wakefulness on intrusive memories. Nine studies were included in our traditional meta-analysis (8 in the IPD meta-analysis). Our analysis provided evidence for a small effect favoring sleep over wakefulness, log-ROM = 0.25, p < .001, suggesting that sleep is associated with a lower number of intrusions but unrelated to the occurrence of any versus no intrusions. We found no evidence for an effect of sleep on intrusion distress. Heterogeneity was low and certainty of evidence for our primary analysis was moderate. Our findings suggest that post-trauma sleep has the potential to be protective by reducing intrusion frequency. More research is needed to determine the impact following real-world trauma and the potential clinical significance.", "doi": "10.1016/j.brat.2023.104359", "pmid": "37422952", "labels": [], "xrefs": [{"db": "pii", "key": "S0005-7967(23)00108-0"}], "notes": [], "created": "2026-09-23T11:18:05.550Z", "modified": "2026-09-23T11:18:05.585Z"}, {"entity": "publication", "iuid": "288eddcefa8d49a0962cbcd21b86b24d", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/288eddcefa8d49a0962cbcd21b86b24d.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/288eddcefa8d49a0962cbcd21b86b24d"}}, "title": "Pavlovian threat conditioning can generate intrusive memories that persist over time.", "authors": [{"family": "Espinosa", "given": "Lisa", "initials": "L"}, {"family": "Bonsall", "given": "Michael B", "initials": "MB"}, {"family": "Becker", "given": "Nina", "initials": "N"}, {"family": "Holmes", "given": "Emily A", "initials": "EA"}, {"family": "Olsson", "given": "Andreas", "initials": "A"}], "type": "journal article", "published": "2022-10-00", "journal": {"title": "Behav Res Ther", "issn": "1873-622X", "volume": "157", "pages": "104161", "issn-l": null}, "abstract": "Although Pavlovian threat conditioning has proven to be a useful translational model for the development of anxiety disorders, it remains unknown if this procedure can generate intrusive memories - a symptom of many anxiety-related disorders, and whether intrusions persist over time. Social support has been related to better adjustment after trauma however, experimental evidence regarding its effect on the development of anxiety-related symptoms is sparse. We had two aims: to test whether threat conditioning generates intrusive memories, and whether different social support interactions impacted expression of emotional memories. Non-clinical participants (n = 81) underwent threat conditioning to neutral stimuli. Participants were then assigned to a supportive, unsupportive, or no social interaction group, and asked to report intrusive memories for seven days. As predicted, threat conditioning can generate intrusions, with greater number of intrusions of CS+ (M = 2.35, SD = 3.09) than CS- (M = 1.39, SD = 2.17). Contrary to predictions, compared to no social interaction, supportive social interaction did not reduce, and unsupportive interaction did not increase skin conductance of learned threat or number of intrusions. Unsupportive interaction resulted in a relative difference in number of intrusions to CS + vs CS-, suggesting that unsupportive interaction might have increased image-based threat memories. Intrusions were still measurable one year after conditioning (one-year follow-up; n = 54), when individuals with higher trait anxiety and greater number of previous trauma experiences reported more intrusions. Our findings show that threat conditioning can create long-lasting intrusions, offering a novel experimental psychopathology model of intrusive memories with implications for both research on learning and clinical applications.", "doi": "10.1016/j.brat.2022.104161", "pmid": "35932550", "labels": [], "xrefs": [{"db": "pii", "key": "S0005-7967(22)00132-2"}], "notes": [], "created": "2026-09-23T12:28:38.283Z", "modified": "2026-09-23T12:28:38.295Z"}, {"entity": "publication", "iuid": "e85843dff49849398e34f9ec6c00640a", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/e85843dff49849398e34f9ec6c00640a.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/e85843dff49849398e34f9ec6c00640a"}}, "title": "A feasibility randomised controlled trial of a brief early intervention for adolescent depression that targets emotional mental images and memory specificity (IMAGINE).", "authors": [{"family": "Pile", "given": "Victoria", "initials": "V"}, {"family": "Smith", "given": "Patrick", "initials": "P"}, {"family": "Leamy", "given": "Mary", "initials": "M"}, {"family": "Oliver", "given": "Abigail", "initials": "A"}, {"family": "Bennett", "given": "Eleanor", "initials": "E"}, {"family": "Blackwell", "given": "Simon E", "initials": "SE"}, {"family": "Meiser-Stedman", "given": "Richard", "initials": "R"}, {"family": "Stringer", "given": "Dominic", "initials": "D"}, {"family": "Dunn", "given": "Barnaby D", "initials": "BD"}, {"family": "Holmes", "given": "Emily A", "initials": "EA"}, {"family": "Lau", "given": "Jennifer Y F", "initials": "JYF"}], "type": "journal article", "published": "2021-08-00", "journal": {"title": "Behav Res Ther", "issn": "1873-622X", "volume": "143", "pages": "103876", "issn-l": null}, "abstract": "Brief, evidence-based interventions for adolescent depression are urgently required, particularly for school-settings. Cognitive mechanisms research suggests dysfunctional mental imagery and overgeneral memory could be promising targets to improve mood. This feasibility randomised controlled trial with parallel symptomatic groups (n = 56) compared a novel imagery-based cognitive behavioural intervention (ICBI) to non-directive supportive therapy (NDST) in school settings. Blind assessments (of clinical symptoms and cognitive mechanisms) took place pre-intervention, post-intervention and follow-up three months later. The trial aimed to evaluate the feasibility and acceptability of the methodology and interventions, and estimate the likely range of effects of the intervention on self-reported depression. The pre-defined criteria for proceeding to a definitive RCT were met: full recruitment occurred within eleven months; retention was 89%; ICBI acceptability was above satisfactory; and no harm was indicated. Intention-to-treat analysis found large effects in favour of ICBI (relative to NDST) at post-intervention in reducing depressive symptoms (d = -1.34, 95% CI [-1.87, -0.80]) and improving memory specificity (d = 0.79 [0.35, 1.23]), a key cognitive target. The findings suggest that ICBI may not only improve mood but also strengthen abilities associated with imagining and planning the future, critical skills at this life stage. A fully powered evaluation of ICBI is warranted. Trial Registration: https://www.isrctn.com/; ISRCTN85369879.", "doi": "10.1016/j.brat.2021.103876", "pmid": "34098409", "labels": [], "xrefs": [{"db": "pii", "key": "S0005-7967(21)00075-9"}, {"db": "ISRCTN", "key": "ISRCTN85369879"}], "notes": [], "created": "2026-09-23T09:35:40.820Z", "modified": "2026-09-23T09:35:40.855Z"}], "created": "2026-09-23T09:35:40.827Z", "modified": "2026-09-23T09:35:40.827Z"}