{"entity": "journal", "iuid": "5802cbdb3dca4744be028b97f288d0fd", "timestamp": "2026-09-24T14:46:57.779Z", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/journal/Acta%20Psychiatr%20Scand.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/journal/Acta%20Psychiatr%20Scand"}}, "title": "Acta Psychiatr Scand", "issn": "1600-0447", "issn-l": null, "publications_count": 2, "publications": [{"entity": "publication", "iuid": "7082e012404d45b18ee84d3636cd7299", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/7082e012404d45b18ee84d3636cd7299.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/7082e012404d45b18ee84d3636cd7299"}}, "title": "Use of hypnotic drugs among children, adolescents, and young adults in Scandinavia.", "authors": [{"family": "Wesselhoeft", "given": "Rikke", "initials": "R", "orcid": "0000-0001-9700-2739", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/29670ecb185844689260deb334d8ef10.json"}}, {"family": "Rasmussen", "given": "Lotte", "initials": "L"}, {"family": "Jensen", "given": "Peter Bj\u00f8dstrup", "initials": "PB"}, {"family": "Jennum", "given": "Poul J\u00f8rgen", "initials": "PJ", "orcid": "0000-0001-6986-5254", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/01b009348f0846beb1d0c60941b1ca28.json"}}, {"family": "Skurtveit", "given": "Svetlana", "initials": "S"}, {"family": "Hartz", "given": "Ingeborg", "initials": "I"}, {"family": "Reutfors", "given": "Johan", "initials": "J", "orcid": "0000-0003-1372-4262", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/dbc162955acf4b2ba0b4dade363d4592.json"}}, {"family": "Damkier", "given": "Per", "initials": "P", "orcid": "0000-0003-0591-7187", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3220b6c562f2497f9122594f270ba2ab.json"}}, {"family": "Bliddal", "given": "Mette", "initials": "M"}, {"family": "Potteg\u00e5rd", "given": "Anton", "initials": "A", "orcid": "0000-0001-9314-5679", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1daf4d9300f94bf6916f968437b52a80.json"}}], "type": "journal article", "published": "2021-08-00", "journal": {"title": "Acta Psychiatr Scand", "issn": "1600-0447", "volume": "144", "issue": "2", "pages": "100-112", "issn-l": null}, "abstract": "Hypnotic use in children and adolescents is controversial.\n\nTo describe the use of hypnotic drugs (melatonin, z-drugs, and sedating antihistamines) among 5- to 24-year-old Scandinavians during 2012 to 2018.\n\nAggregate-level data were obtained from public data sources in Sweden, Norway, and Denmark. We calculated annual prevalence (users/1000 inhabitants) stratified by age group, sex, and country. Quantity of use (Defined Daily Dose (DDD)/user/day) was estimated for Norway and Denmark.\n\nMelatonin was the most commonly used hypnotic, and its use increased markedly from 2012 to 2018, particularly among females and 15- to 24-year-old individuals. Sweden had the highest increase in use (6.5 to 25/1000) compared with Norway (10-20/1000) and Denmark (5.7-12/1000). The annual prevalence of sedating antihistamine use was also highest in Sweden, reaching 13/1000 in 2018 in comparison to 7.5/1000 in Norway and 2.5/1000 in Denmark. Z-drug use decreased in all countries toward 2018, dropping to 3.5/1000 in Sweden, 4.4/1000 in Norway, and 1.7/1000 in Denmark. The quantity of hypnotic use in Norway and Denmark was 0.8-1.0 DDD/user/day for melatonin in 2018, as compared to 0.1-0.3 for z-drugs and antihistamines.\n\nThe use of melatonin and sedating antihistamines increased among young Scandinavians during 2012-2018, and the increase was twice as high in Sweden compared with Norway and Denmark. In addition, Sweden had the highest use of sedating antihistamines. The Scandinavian variation of hypnotic use could reflect differences in frequency of sleep problems between populations or variation of healthcare access or clinical practice between countries.", "doi": "10.1111/acps.13329", "pmid": "34021908", "labels": [], "xrefs": [], "notes": [], "created": "2026-09-23T09:59:52.674Z", "modified": "2026-09-23T10:37:29.122Z"}, {"entity": "publication", "iuid": "50017f7dc1534a7bb3cb353746fa8c43", "links": {"self": {"href": "https://publications-affiliated.scilifelab.se/publication/50017f7dc1534a7bb3cb353746fa8c43.json"}, "display": {"href": "https://publications-affiliated.scilifelab.se/publication/50017f7dc1534a7bb3cb353746fa8c43"}}, "title": "Trends in antidepressant use among children and adolescents: a Scandinavian drug utilization study.", "authors": [{"family": "Wesselhoeft", "given": "R", "initials": "R", "orcid": "0000-0001-9700-2739", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/29670ecb185844689260deb334d8ef10.json"}}, {"family": "Jensen", "given": "P B", "initials": "PB"}, {"family": "Talati", "given": "A", "initials": "A"}, {"family": "Reutfors", "given": "J", "initials": "J"}, {"family": "Furu", "given": "K", "initials": "K"}, {"family": "Strandberg-Larsen", "given": "K", "initials": "K"}, {"family": "Damkier", "given": "P", "initials": "P", "orcid": "0000-0003-0591-7187", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/3220b6c562f2497f9122594f270ba2ab.json"}}, {"family": "Potteg\u00e5rd", "given": "A", "initials": "A", "orcid": "0000-0001-9314-5679", "researcher": {"href": "https://publications-affiliated.scilifelab.se/researcher/1daf4d9300f94bf6916f968437b52a80.json"}}, {"family": "Bliddal", "given": "M", "initials": "M"}], "type": "journal article", "published": "2020-01-00", "journal": {"title": "Acta Psychiatr Scand", "issn": "1600-0447", "volume": "141", "issue": "1", "pages": "34-42", "issn-l": null}, "abstract": "To compare antidepressant utilization in individuals aged 5-19 years from the Scandinavian countries.\n\nA population-based drug utilization study using publicly available data of antidepressant use from Denmark, Norway, and Sweden.\n\nIn the study period from 2007 to 2017, the proportion of antidepressant users increased markedly in Sweden (9.3-18.0/1000) compared to Norway (5.1-7.6/1000) and Denmark (9.3-7.5/1000). In 2017, the cumulated defined daily doses (DDD) of selective serotonin reuptake inhibitors were 5611/1000 inhabitants in Sweden, 2709/1000 in Denmark, and 1848/1000 in Norway. The use of 'other antidepressants' (ATC code N06AX) also increased in Sweden with a higher DDD in 2017 (497/1000) compared to Denmark (225/1000) and Norway (170/1000). The use of tricyclic antidepressants was generally low in 2017 with DDDs ranging between 30-42 per 1000. The proportion of antidepressant users was highest among 15- to 19-year-old individuals. Girls were more likely to receive treatment than boys, and the treated female/male ratios per 1000 were similar in Sweden (2.39), Denmark (2.44), and Norway (2.63).\n\nEven in highly comparable healthcare systems like the Scandinavian countries', variation in antidepressant use is considerable. Swedish children and adolescents have a markedly higher and still increasing use of antidepressants compared to Danish and Norwegian peers.", "doi": "10.1111/acps.13116", "pmid": "31618447", "labels": [], "xrefs": [], "notes": [], "created": "2026-09-23T08:43:15.599Z", "modified": "2026-09-23T08:43:15.848Z"}], "created": "2026-09-23T08:43:15.789Z", "modified": "2026-09-23T08:43:15.789Z"}